메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages 1259-1266

Peroxisome proliferator-activated receptor-γ is downregulated in ulcerative colitis and is involved in experimental colitis-associated neoplasia

Author keywords

5 aminosalicylic acid; Colonic neoplasms; Peroxisome proliferator activated receptor ; Ulcerative colitis

Indexed keywords

AZOXYMETHANE; DEXTRAN SULFATE; MESALAZINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 84937393858     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2015.3397     Document Type: Article
Times cited : (32)

References (35)
  • 1
    • 0141651527 scopus 로고    scopus 로고
    • Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease
    • Munkholm P: Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease. Aliment Pharmacol Ther 18(Suppl 2): 1-5, 2003.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 1-5
    • Munkholm, P.1
  • 2
    • 12344297411 scopus 로고    scopus 로고
    • 5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease
    • Cheng Y and Desreumaux P: 5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease. World J Gastroenterol11: 309-314, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 309-314
    • Cheng, Y.1    Desreumaux, P.2
  • 3
    • 0035094340 scopus 로고    scopus 로고
    • The pleiotropic functions of peroxisome proliferator-activated receptor gamma
    • Debril MB, Renaud JP, Fajas L and Auwerx J: The pleiotropic functions of peroxisome proliferator-activated receptor gamma. J Mol Med Berl 79: 30-47, 2001.
    • (2001) J Mol Med Berl , vol.79 , pp. 30-47
    • Debril, M.B.1    Renaud, J.P.2    Fajas, L.3    Auwerx, J.4
  • 4
    • 33847403883 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is required for regulatory CD4+ Tcell-mediated protection against colitis
    • Hontecillas R and Bassaganya-Riera J: Peroxisome proliferator-activated receptor gamma is required for regulatory CD4+ Tcell-mediated protection against colitis. J Immunol 178: 2940-2949, 2007.
    • (2007) J Immunol , vol.178 , pp. 2940-2949
    • Hontecillas, R.1    Bassaganya-Riera, J.2
  • 5
    • 49349100984 scopus 로고    scopus 로고
    • PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells
    • Schwab M, Reynders V, Loitsch S, Shastri YM, SteinhilberD, Schröder O and Stein J: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells. Carcinogenesis 29: 1407-1414, 2008.
    • (2008) Carcinogenesis , vol.29 , pp. 1407-1414
    • Schwab, M.1    Reynders, V.2    Loitsch, S.3    Shastri, Y.M.4    Steinhilber, D.5    Schröder, O.6    Stein, J.7
  • 6
    • 25144459131 scopus 로고    scopus 로고
    • 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: A large epidemiological study
    • van Staa TP, Card T, Logan RF and Leufkens HG: 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: A large epidemiological study. Gut 54: 1573-1578, 2005.
    • (2005) Gut , vol.54 , pp. 1573-1578
    • van Staa, T.P.1    Card, T.2    Logan, R.F.3    Leufkens, H.G.4
  • 9
    • 25144490062 scopus 로고    scopus 로고
    • Suppression of colitis-related mouse colon carcinogenesis by a COX-2inhibitor and PPAR ligands
    • Kohno H, Suzuki R, Sugie S and Tanaka T: Suppression of colitis-related mouse colon carcinogenesis by a COX-2inhibitor and PPAR ligands. BMC Cancer 5: 46, 2005.
    • (2005) BMC Cancer , vol.5 , pp. 46
    • Kohno, H.1    Suzuki, R.2    Sugie, S.3    Tanaka, T.4
  • 10
    • 0027224059 scopus 로고
    • Clinicopathologic study of dextran sulfate sodium experimental murine colitis
    • Cooper HS, Murthy SN, Shah RS and Sedergran DJ: Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249, 1993.
    • (1993) Lab Invest , vol.69 , pp. 238-249
    • Cooper, H.S.1    Murthy, S.N.2    Shah, R.S.3    Sedergran, D.J.4
  • 11
    • 0029791910 scopus 로고    scopus 로고
    • Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes
    • Ni J, Chen SF and Hollander D: Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes. Gut 39: 234-241, 1996.
    • (1996) Gut , vol.39 , pp. 234-241
    • Ni, J.1    Chen, S.F.2    Hollander, D.3
  • 12
    • 0035206705 scopus 로고    scopus 로고
    • The role of mutant Apc in the development of dysplasia and cancer in the mouse model of dextran sulfate sodium-induced colitis
    • Cooper HS, Everley L, Chang WC, Pfeiffer G, Lee B, Murthy S and Clapper ML: The role of mutant Apc in the development of dysplasia and cancer in the mouse model of dextran sulfate sodium-induced colitis. Gastroenterology 121: 1407-1416, 2001.
    • (2001) Gastroenterology , vol.121 , pp. 1407-1416
    • Cooper, H.S.1    Everley, L.2    Chang, W.C.3    Pfeiffer, G.4    Lee, B.5    Murthy, S.6    Clapper, M.L.7
  • 13
    • 27944442806 scopus 로고    scopus 로고
    • Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
    • Tanaka T, Kohno H, Suzuki R, Hata K, Sugie S, Niho N, SakanoK, Takahashi M and Wakabayashi K: Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int J Cancer 118: 25-34, 2006.
    • (2006) Int J Cancer , vol.118 , pp. 25-34
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3    Hata, K.4    Sugie, S.5    Niho, N.6    Sakano, K.7    Takahashi, M.8    Wakabayashi, K.9
  • 14
    • 0034124076 scopus 로고    scopus 로고
    • Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis
    • Murano M, Maemura K, Hirata I, Toshina K, Nishikawa T, Hamamoto N, Sasaki S, Saitoh O and Katsu K: Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis. Clin Exp Immunol 120: 51-58, 2000.
    • (2000) Clin Exp Immunol , vol.120 , pp. 51-58
    • Murano, M.1    Maemura, K.2    Hirata, I.3    Toshina, K.4    Nishikawa, T.5    Hamamoto, N.6    Sasaki, S.7    Saitoh, O.8    Katsu, K.9
  • 15
    • 0018297607 scopus 로고
    • Bacteriological studies of experimental ulcerative colitis
    • Onderdonk AB and Bartlett JG: Bacteriological studies of experimental ulcerative colitis. Am J Clin Nutr 32: 258-265, 1979.
    • (1979) Am J Clin Nutr , vol.32 , pp. 258-265
    • Onderdonk, A.B.1    Bartlett, J.G.2
  • 16
    • 84911496124 scopus 로고    scopus 로고
    • Decreased expression of histone deacetylase10 predicts poor prognosis of gastric cancer patients
    • JinZ, JiangW, JiaoF, HuH, GuoZ, WangL and WangL: Decreased expression of histone deacetylase10 predicts poor prognosis of gastric cancer patients, Int J Clin Exp Pathol7: 5872-5879, 2014.
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 5872-5879
    • Jin, Z.1    Jiang, W.2    Jiao, F.3    Hu, H.4    Guo, Z.5    Wang, L.6    Wang, L.7
  • 17
    • 0037010478 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases
    • Dubuquoy L, Dharancy S, Nutten S, Pettersson S, Auwerx J and Desreumaux P: Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases. Lancet 360: 1410-1418, 2002.
    • (2002) Lancet , vol.360 , pp. 1410-1418
    • Dubuquoy, L.1    Dharancy, S.2    Nutten, S.3    Pettersson, S.4    Auwerx, J.5    Desreumaux, P.6
  • 19
    • 3042815666 scopus 로고    scopus 로고
    • Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists
    • Grommes C, Landreth GE and Heneka MT: Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists. Lancet Oncol 5: 419-429, 2004.
    • (2004) Lancet Oncol , vol.5 , pp. 419-429
    • Grommes, C.1    Landreth, G.E.2    Heneka, M.T.3
  • 20
    • 0038448230 scopus 로고    scopus 로고
    • Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1signaling pathway
    • Chen CW, Chang YH, Tsi CJ and Lin WW: Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1signaling pathway. JImmunol171: 979-988, 2003.
    • (2003) JImmunol , vol.171 , pp. 979-988
    • Chen, C.W.1    Chang, Y.H.2    Tsi, C.J.3    Lin, W.W.4
  • 21
    • 20344363144 scopus 로고    scopus 로고
    • Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats
    • Sánchez-Hidalgo M, Martín AR, Villegas I and Alarcón De La Lastra C: Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats. Biochem Pharmacol 69: 1733-1744, 2005.
    • (2005) Biochem Pharmacol , vol.69 , pp. 1733-1744
    • Sánchez-Hidalgo, M.1    Martín, A.R.2    Villegas, I.3    Alarcón De La Lastra, C.4
  • 22
    • 0001297403 scopus 로고    scopus 로고
    • Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT
    • Yang XY, Wang LH, Chen T, Hodge DR, Resau JH, DaSilva L and Farrar WL: Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT. J Biol Chem 275: 4541-4544, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 4541-4544
    • Yang, X.Y.1    Wang, L.H.2    Chen, T.3    Hodge, D.R.4    Resau, J.H.5    Da Silva, L.6    Farrar, W.L.7
  • 23
    • 35448982383 scopus 로고    scopus 로고
    • Biology of PPAR gamma in cancer: A critical review on existing lacunae
    • Krishnan A, Nair SA and Pillai MR: Biology of PPAR gamma in cancer: A critical review on existing lacunae. Curr Mol Med7: 532-540, 2007.
    • (2007) Curr Mol Med , vol.7 , pp. 532-540
    • Krishnan, A.1    Nair, S.A.2    Pillai, M.R.3
  • 28
    • 67650109585 scopus 로고    scopus 로고
    • 5-Aminosalicylic acid inhibits colitis-associated but not sporadic colorectal neoplasia in a novel conditional Apc mouse model
    • Koelink PJ, Robanus-Maandag EC, Devilee P, Hommes DW, Lamers CB and Verspaget HW: 5-Aminosalicylic acid inhibits colitis-associated but not sporadic colorectal neoplasia in a novel conditional Apc mouse model. Carcinogenesis 30: 1217-1224, 2009.
    • (2009) Carcinogenesis , vol.30 , pp. 1217-1224
    • Koelink, P.J.1    Robanus-Maandag, E.C.2    Devilee, P.3    Hommes, D.W.4    Lamers, C.B.5    Verspaget, H.W.6
  • 30
    • 57149109314 scopus 로고    scopus 로고
    • 5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis
    • Clapper ML, Gary MA, Coudry RA, Litwin S, Chang WC, Devarajan K, Lubet RA and Cooper HS: 5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis. Inflamm Bowel Dis 14: 1341-1347, 2008.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1341-1347
    • Clapper, M.L.1    Gary, M.A.2    Coudry, R.A.3    Litwin, S.4    Chang, W.C.5    Devarajan, K.6    Lubet, R.A.7    Cooper, H.S.8
  • 31
    • 77953626157 scopus 로고    scopus 로고
    • Biology of colorectal cancer
    • Saif MW and Chu E: Biology of colorectal cancer. Cancer J 16: 196-201, 2010.
    • (2010) Cancer J , vol.16 , pp. 196-201
    • Saif, M.W.1    Chu, E.2
  • 32
    • 7244232742 scopus 로고    scopus 로고
    • Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes
    • Liu J and Farmer SR: Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes. J Biol Chem 279: 45020-45027, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 45020-45027
    • Liu, J.1    Farmer, S.R.2
  • 33
    • 67149141753 scopus 로고    scopus 로고
    • Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease
    • Atug O, Tahan V, Eren F, Tiftikci A, Imeryuz N, Hamzaoglu HO and Tozun N: Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease. J Gastrointestin Liver Dis 17: 433-437, 2008.
    • (2008) J Gastrointestin Liver Dis , vol.17 , pp. 433-437
    • Atug, O.1    Tahan, V.2    Eren, F.3    Tiftikci, A.4    Imeryuz, N.5    Hamzaoglu, H.O.6    Tozun, N.7
  • 35
    • 77951219696 scopus 로고    scopus 로고
    • MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization
    • Jennewein C, von Knethen A, Schmid T and BrüneB: MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization. JBiol Chem285: 11846-11853, 2010.
    • (2010) JBiol Chem , vol.285 , pp. 11846-11853
    • Jennewein, C.1    von Knethen, A.2    Schmid, T.3    Brüne, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.