-
1
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group (EBCTCG): Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. Lancet 365:1687-1717, 2005
-
(2005)
Lancet
, vol.365
, pp. 1687-1717
-
-
-
2
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al: Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344:783-792, 2001
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
3
-
-
34247569300
-
Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: A population-based study from the California Cancer Registry
-
Bauer KR, Brown M, Cress RD, et al: Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: A population-based study from the California Cancer Registry. Cancer 109:1721-1728, 2007
-
(2007)
Cancer
, vol.109
, pp. 1721-1728
-
-
Bauer, K.R.1
Brown, M.2
Cress, R.D.3
-
4
-
-
70349118046
-
Clinical relevance of the triple-negative breast cancer concept: Genetic basis and clinical utility of the concept
-
Linn SC, Van't Veer LJ: Clinical relevance of the triple-negative breast cancer concept: Genetic basis and clinical utility of the concept. Eur J Cancer 45:11-26, 2009
-
(2009)
Eur J Cancer
, vol.45
, pp. 11-26
-
-
Linn, S.C.1
Van'T Veer, L.J.2
-
5
-
-
79959503213
-
Triple-negative breast cancer: An unmet medical need
-
Hudis CA, Gianni L: Triple-negative breast cancer: An unmet medical need. Oncologist 16:1-11, 2011
-
(2011)
Oncologist
, vol.16
, pp. 1-11
-
-
Hudis, C.A.1
Gianni, L.2
-
6
-
-
84919383828
-
Subtyping of triple-negative breast cancer: Implications for therapy
-
Abramson VG, Lehmann BD, Ballinger TJ, et al: Subtyping of triple-negative breast cancer: Implications for therapy. Cancer 121:8-16, 2015
-
(2015)
Cancer
, vol.121
, pp. 8-16
-
-
Abramson, V.G.1
Lehmann, B.D.2
Ballinger, T.J.3
-
7
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner N, Tutt A, Ashworth A: Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev Cancer 4:814-819, 2004
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 814-819
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
8
-
-
56049103793
-
Understanding and treating triple-negative breast cancer
-
discussion 1239-1240, 1243
-
Anders C, Carey LA: Understanding and treating triple-negative breast cancer. Oncology (Williston Park) 22:1233-1239, 2008; discussion 1239-1240, 1243
-
(2008)
Oncology (Williston Park)
, vol.22
, pp. 1233-1239
-
-
Anders, C.1
Carey, L.A.2
-
9
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network: Comprehensive molecular portraits of human breast tumours. Nature 490:61-70, 2012
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
Cancer Genome Atlas Network1
-
10
-
-
0033213392
-
Brca1 controls homology-directed DNA repair
-
Moynahan ME, Chiu JW, Koller BH, et al: Brca1 controls homology-directed DNA repair. Mol Cell 4:511-518, 1999
-
(1999)
Mol Cell
, vol.4
, pp. 511-518
-
-
Moynahan, M.E.1
Chiu, J.W.2
Koller, B.H.3
-
11
-
-
63049108452
-
Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment
-
Venkitaraman AR: Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment. Annu Rev Pathol 4:461-487, 2009
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 461-487
-
-
Venkitaraman, A.R.1
-
12
-
-
78649336706
-
The DNA damage response: Making it safe to play with knives
-
Ciccia A, Elledge SJ: The DNA damage response: Making it safe to play with knives. Mol Cell 40:179-204, 2010
-
(2010)
Mol Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
13
-
-
79959635260
-
DNA interstrand crosslink repair and cancer
-
Deans AJ, West SC: DNA interstrand crosslink repair and cancer. Nat Rev Cancer 11:467-480, 2011
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 467-480
-
-
Deans, A.J.1
West, S.C.2
-
14
-
-
77953636534
-
Homologous recombination in cancer development, treatment and development of drug resistance
-
Helleday T: Homologous recombination in cancer development, treatment and development of drug resistance. Carcinogenesis 31:955-960, 2010
-
(2010)
Carcinogenesis
, vol.31
, pp. 955-960
-
-
Helleday, T.1
-
15
-
-
84901587677
-
Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): A randomised phase 2 trial
-
Von Minckwitz G, Schneeweiss A, Loibl S, et al: Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): A randomised phase 2 trial. Lancet Oncol 15:747-756, 2014
-
(2014)
Lancet Oncol
, vol.15
, pp. 747-756
-
-
Von Minckwitz, G.1
Schneeweiss, A.2
Loibl, S.3
-
16
-
-
84920569142
-
Impact of the addition of carboplatin and/or bevacizumab to neoadjuvant once-per-week paclitaxel followed by dose-dense doxorubicin and cyclophosphamide on pathologic complete response rates in stage II to III triple-negative breast cancer: CALGB 40603 (Alliance)
-
Sikov WM, Berry DA, Perou CM, et al: Impact of the addition of carboplatin and/or bevacizumab to neoadjuvant once-per-week paclitaxel followed by dose-dense doxorubicin and cyclophosphamide on pathologic complete response rates in stage II to III triple-negative breast cancer: CALGB 40603 (Alliance). J Clin Oncol 33:13-21, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 13-21
-
-
Sikov, W.M.1
Berry, D.A.2
Perou, C.M.3
-
17
-
-
84920621382
-
Defining a role and predicting benefit from platinum-based therapy in breast cancer: An evolving story
-
Sparano JA: Defining a role and predicting benefit from platinum-based therapy in breast cancer: An evolving story. J Clin Oncol 33:1-3, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 1-3
-
-
Sparano, J.A.1
-
18
-
-
84937144479
-
Phase II study of gemcitabine, carboplatin, and iniparib as neoadjuvant therapy for triple-negative and BRCA1/2 mutation-associated breast cancer with assessment of a tumor-based measure of genomic instability: PrECOG 0105
-
Telli ML, Jensen KC, Vinayak S, et al: Phase II study of gemcitabine, carboplatin, and iniparib as neoadjuvant therapy for triple-negative and BRCA1/2 mutation-associated breast cancer with assessment of a tumor-based measure of genomic instability: PrECOG 0105. J Clin Oncol 33:1895-1901, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 1895-1901
-
-
Telli, M.L.1
Jensen, K.C.2
Vinayak, S.3
-
19
-
-
84937145516
-
TBCRC009: A multicenter phase II clinical trial of platinum monotherapy with biomarker assessment in metastatic triple-negative breast cancer
-
Isakoff SJ, Mayer EL, He L, et al: TBCRC009: A multicenter phase II clinical trial of platinum monotherapy with biomarker assessment in metastatic triple-negative breast cancer. J Clin Oncol 33:1902-1909, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 1902-1909
-
-
Isakoff, S.J.1
Mayer, E.L.2
He, L.3
-
20
-
-
84869079205
-
Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
-
Abkevich V, Timms KM, Hennessy BT, et al: Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer. Br J Cancer 107:1776-1782, 2012
-
(2012)
Br J Cancer
, vol.107
, pp. 1776-1782
-
-
Abkevich, V.1
Timms, K.M.2
Hennessy, B.T.3
-
21
-
-
84868240146
-
Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation
-
Popova T, Manié E, Rieunier G, et al: Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation. Cancer Res 72:5454-5462, 2012
-
(2012)
Cancer Res
, vol.72
, pp. 5454-5462
-
-
Popova, T.1
Manié, E.2
Rieunier, G.3
-
22
-
-
84901664854
-
Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers
-
Watkins JA, Irshad S, Grigoriadis A, et al: Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers. Breast Cancer Res 16:211, 2014
-
(2014)
Breast Cancer Res
, vol.16
, pp. 211
-
-
Watkins, J.A.1
Irshad, S.2
Grigoriadis, A.3
-
23
-
-
84866532392
-
Systemic therapy options in BRCA mutation-associated breast cancer
-
Bayraktar S, Glück S: Systemic therapy options in BRCA mutation-associated breast cancer. Breast Cancer Res Treat 135:355-366, 2012
-
(2012)
Breast Cancer Res Treat
, vol.135
, pp. 355-366
-
-
Bayraktar, S.1
Glück, S.2
-
25
-
-
84884129399
-
Breast cancer in women at high risk: The role of rapid genetic testing for BRCA1 and -2 mutations and the consequences for treatment strategies
-
Francken AB, Schouten PC, Bleiker EM, et al: Breast cancer in women at high risk: The role of rapid genetic testing for BRCA1 and -2 mutations and the consequences for treatment strategies. Breast 22:561-568, 2013
-
(2013)
Breast
, vol.22
, pp. 561-568
-
-
Francken, A.B.1
Schouten, P.C.2
Bleiker, E.M.3
-
26
-
-
70449420123
-
Use of archived specimens in evaluation of prognostic and predictive biomarkers
-
Simon RM, Paik S, Hayes DF: Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst 101:1446-1452, 2009
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1446-1452
-
-
Simon, R.M.1
Paik, S.2
Hayes, D.F.3
-
27
-
-
33745641883
-
Uses and abuses of tumor markers in the diagnosis, monitoring, and treatment of primary and metastatic breast cancer
-
Henry NL, Hayes DF: Uses and abuses of tumor markers in the diagnosis, monitoring, and treatment of primary and metastatic breast cancer. Oncologist 11:541-552, 2006
-
(2006)
Oncologist
, vol.11
, pp. 541-552
-
-
Henry, N.L.1
Hayes, D.F.2
-
28
-
-
15744374441
-
Clinical trial designs for predictive marker validation in cancer treatment trials
-
Sargent DJ, Conley BA, Allegra C, et al: Clinical trial designs for predictive marker validation in cancer treatment trials. J Clin Oncol 23:2020-2027, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 2020-2027
-
-
Sargent, D.J.1
Conley, B.A.2
Allegra, C.3
-
29
-
-
67651030311
-
Clinical trial designs for predictive biomarker validation: One size does not fit all
-
Mandrekar SJ, Sargent DJ: Clinical trial designs for predictive biomarker validation: One size does not fit all. J Biopharm Stat 19:530-542, 2009
-
(2009)
J Biopharm Stat
, vol.19
, pp. 530-542
-
-
Mandrekar, S.J.1
Sargent, D.J.2
-
30
-
-
33750310901
-
REporting recommendations for tumor MARKer prognostic studies (REMARK)
-
McShane LM, Altman DG, Sauerbrei W, et al: REporting recommendations for tumor MARKer prognostic studies (REMARK). Breast Cancer Res Treat 100:229-235, 2006
-
(2006)
Breast Cancer Res Treat
, vol.100
, pp. 229-235
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
-
31
-
-
84861543054
-
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and elaboration
-
Altman DG, McShane LM, Sauerbrei W, et al: Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and elaboration. PLoS Med 9:e1001216, 2012
-
(2012)
PLoS Med
, vol.9
-
-
Altman, D.G.1
McShane, L.M.2
Sauerbrei, W.3
-
32
-
-
84923177854
-
Breast cancers with a BRCA1-like DNA copy number profile recur less often than expected after high-dose alkylating chemotherapy
-
Schouten PC, Marmé F, Aulmann S, et al: Breast cancers with a BRCA1-like DNA copy number profile recur less often than expected after high-dose alkylating chemotherapy. Clin Cancer Res 21:763-770, 2015
-
(2015)
Clin Cancer Res
, vol.21
, pp. 763-770
-
-
Schouten, P.C.1
Marmé, F.2
Aulmann, S.3
-
33
-
-
84934291165
-
TNT: A randomized phase III trial of carboplatin (C) compared with docetaxel (D) for patients with metastatic or recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012)
-
abstr S3-01
-
th Annual San Antonio Breast Cancer Symposium, San Antonio, TX, December 9-13, 2014 (abstr S3-01)
-
(2014)
th Annual San Antonio Breast Cancer Symposium, San Antonio, TX, December 9-13
-
-
Tutt, A.1
Ellis, P.2
Kilburn, L.3
-
34
-
-
84866261844
-
Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents
-
Birkbak NJ, Wang ZC, Kim JY, et al: Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents. Cancer Discov 2:366-375, 2012
-
(2012)
Cancer Discov
, vol.2
, pp. 366-375
-
-
Birkbak, N.J.1
Wang, Z.C.2
Kim, J.Y.3
-
35
-
-
84924259541
-
Association of BRCA1/2 defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes
-
Timms KM, Abkevich V, Hughes E, et al: Association of BRCA1/2 defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes. Breast Cancer Res 16:475, 2014
-
(2014)
Breast Cancer Res
, vol.16
, pp. 475
-
-
Timms, K.M.1
Abkevich, V.2
Hughes, E.3
-
36
-
-
84937146628
-
Evaluation of a BRCAness signature as a predictive biomarker of response to veliparib/carboplatin plus standard neoadjuvant therapy in high-risk breast cancer: Results from the I-SPY 2 TRIAL
-
Glas A, Peeters J, Yau C, et al: Evaluation of a BRCAness signature as a predictive biomarker of response to veliparib/carboplatin plus standard neoadjuvant therapy in high-risk breast cancer: Results from the I-SPY 2 TRIAL. Eur J Cancer 50:173, 2014
-
(2014)
Eur J Cancer
, vol.50
, pp. 173
-
-
Glas, A.1
Peeters, J.2
Yau, C.3
-
37
-
-
79959733228
-
An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients
-
Vollebergh MA, Lips EH, Nederlof PM, et al: An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients. Ann Oncol 22:1561-1570, 2011
-
(2011)
Ann Oncol
, vol.22
, pp. 1561-1570
-
-
Vollebergh, M.A.1
Lips, E.H.2
Nederlof, P.M.3
-
38
-
-
84937151183
-
BRCA1-like copy number profiles to predict benefit of high-dose alkylating chemotherapy in high-risk breast cancer (BC): Results from randomized WSG AM-01 trial
-
abstr 11018
-
Schouten PC, Gluz O, Harbeck N, et al: BRCA1-like copy number profiles to predict benefit of high-dose alkylating chemotherapy in high-risk breast cancer (BC): Results from randomized WSG AM-01 trial. J Clin Oncol 32, 2014 (suppl 5s; abstr 11018)
-
(2014)
J Clin Oncol
, vol.32
-
-
Schouten, P.C.1
Gluz, O.2
Harbeck, N.3
|