메뉴 건너뛰기




Volumn 70, Issue 7, 2015, Pages 2038-2047

Challenges to accurate susceptibility testing and interpretation of quinolone resistance in Enterobacteriaceae: Results of a Spanish multicentre study

Author keywords

Aac(6') Ib cr; Efflux pumps; OqxAB; Porins; QepA; Qnr; QRDR

Indexed keywords

CIPROFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; NALIDIXIC ACID; NORFLOXACIN; OFLOXACIN; QUINOLONE; QUINOLONE DERIVATIVE;

EID: 84936934325     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv059     Document Type: Article
Times cited : (6)

References (33)
  • 1
    • 74049088254 scopus 로고    scopus 로고
    • Quinolones: action and resistance updated
    • Drlica K, Hiasa H, Kerns R et al. Quinolones: action and resistance updated. Curr Top Med Chem 2009; 9: 981-98.
    • (2009) Curr Top Med Chem , vol.9 , pp. 981-998
    • Drlica, K.1    Hiasa, H.2    Kerns, R.3
  • 2
    • 84863366486 scopus 로고    scopus 로고
    • Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli
    • Singh R, Swick MC, Ledesma KR et al. Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli. Antimicrob Agents Chemother 2012; 56: 1680-5.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1680-1685
    • Singh, R.1    Swick, M.C.2    Ledesma, K.R.3
  • 3
    • 70449111402 scopus 로고    scopus 로고
    • Plasmid-mediated quinolone resistance: a multifaceted threat
    • Strahilevitz J, Jacoby GA, Hooper DC et al. Plasmid-mediated quinolone resistance: a multifaceted threat. Clin Microbiol Rev 2009; 22: 664-89.
    • (2009) Clin Microbiol Rev , vol.22 , pp. 664-689
    • Strahilevitz, J.1    Jacoby, G.A.2    Hooper, D.C.3
  • 5
    • 84884973243 scopus 로고    scopus 로고
    • Resistant Gram-negative infections
    • Fraimow H, Nahra R. Resistant Gram-negative infections. Crit Care Clin 2013; 29: 895-921.
    • (2013) Crit Care Clin , vol.29 , pp. 895-921
    • Fraimow, H.1    Nahra, R.2
  • 6
    • 51549085531 scopus 로고    scopus 로고
    • Impact of antibiotic resistance in Gram-negative bacilli on empirical and definitive antibiotic therapy
    • Paterson DL. Impact of antibiotic resistance in Gram-negative bacilli on empirical and definitive antibiotic therapy. Clin Infect Dis 2008; 47 Suppl 1: S14-20.
    • (2008) Clin Infect Dis , vol.47 , pp. S14-S20
    • Paterson, D.L.1
  • 7
    • 77955435461 scopus 로고    scopus 로고
    • Comparison of BDPhoenix, Vitek 2, and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae
    • Woodford N, Eastaway AT, FordM et al. Comparison of BDPhoenix, Vitek 2, and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae. J Clin Microbiol 2010; 48: 2999-3002.
    • (2010) J Clin Microbiol , vol.48 , pp. 2999-3002
    • Woodford, N.1    Eastaway, A.T.2    Ford, M.3
  • 8
    • 0038290378 scopus 로고    scopus 로고
    • Quality control for β-lactam susceptibility testing with a well-defined collection of Enterobacteriaceae and Pseudomonas aeruginosa strains in Spain
    • Canton R, Loza E, Del Carmen ConejoMet al. Quality control for β-lactam susceptibility testing with a well-defined collection of Enterobacteriaceae and Pseudomonas aeruginosa strains in Spain. J Clin Microbiol 2003; 41: 1912-8.
    • (2003) J Clin Microbiol , vol.41 , pp. 1912-1918
    • Canton, R.1    Loza, E.2    Del Carmen Conejo, M.3
  • 9
    • 84873587593 scopus 로고    scopus 로고
    • Challenges for accurate susceptibility testing, detection and interpretation of β-lactam resistance phenotypes in Pseudomonas aeruginosa: results from a Spanish multicentre study
    • Juan C, Conejo MC, Tormo N et al. Challenges for accurate susceptibility testing, detection and interpretation of β-lactam resistance phenotypes in Pseudomonas aeruginosa: results from a Spanish multicentre study. J Antimicrob Chemother 2013; 68: 619-30.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 619-630
    • Juan, C.1    Conejo, M.C.2    Tormo, N.3
  • 13
    • 0035038683 scopus 로고    scopus 로고
    • Emerging mechanisms of fluoroquinolone resistance
    • Hooper DC. Emerging mechanisms of fluoroquinolone resistance. Emerg Infect Dis 2001; 7: 337-41.
    • (2001) Emerg Infect Dis , vol.7 , pp. 337-341
    • Hooper, D.C.1
  • 14
    • 21844477302 scopus 로고    scopus 로고
    • Mechanisms of resistance to quinolones
    • Jacoby GA. Mechanisms of resistance to quinolones. Clin Infect Dis 2005; 41 Suppl 2: S120-6.
    • (2005) Clin Infect Dis , vol.41 , pp. S120-S126
    • Jacoby, G.A.1
  • 16
    • 79956013617 scopus 로고    scopus 로고
    • Discrepancies in fluoroquinolone clinical categories between the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and CLSI for Escherichia coli harbouring qnr genes and mutations in gyrA and parC
    • Rodriguez-Martinez JM, Briales A, Velasco C et al. Discrepancies in fluoroquinolone clinical categories between the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and CLSI for Escherichia coli harbouring qnr genes and mutations in gyrA and parC. J Antimicrob Chemother 2011; 66: 1405-7.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 1405-1407
    • Rodriguez-Martinez, J.M.1    Briales, A.2    Velasco, C.3
  • 17
    • 33645779030 scopus 로고    scopus 로고
    • In vivo selection of fluoroquinoloneresistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum β-lactamase
    • Poirel L, Pitout JD, Calvo L et al. In vivo selection of fluoroquinoloneresistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum β-lactamase. Antimicrob Agents Chemother 2006; 50: 1525-7.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1525-1527
    • Poirel, L.1    Pitout, J.D.2    Calvo, L.3
  • 18
    • 0141781235 scopus 로고    scopus 로고
    • Fluoroquinolone AUIC break points and the link to bacterial killing rate: human trials
    • Schentag JJ, Meagher AK, Forrest A. Fluoroquinolone AUIC break points and the link to bacterial killing rates. Part 2: human trials. Ann Pharmacother 2003; 37: 1478-88.
    • (2003) Ann Pharmacother , vol.37 , pp. 1478-1488
    • Schentag, J.J.1    Meagher, A.K.2    Forrest, A.3
  • 19
    • 84929342177 scopus 로고    scopus 로고
    • Interplay between plasmidmediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli
    • Machuca J, Briales A, Labrador G et al. Interplay between plasmidmediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli. J Antimicrob Chemother 2014; 69: 3203-15.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 3203-3215
    • Machuca, J.1    Briales, A.2    Labrador, G.3
  • 20
    • 69949103098 scopus 로고    scopus 로고
    • Evaluation of quinolones for use in detection of determinants of acquired quinolone resistance, including the new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6')Ib-cr, in Escherichia coli and Salmonella enterica and determinations of wild-type distributions
    • Cavaco LM, Aarestrup FM. Evaluation of quinolones for use in detection of determinants of acquired quinolone resistance, including the new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6')Ib-cr, in Escherichia coli and Salmonella enterica and determinations of wild-type distributions. J Clin Microbiol 2009; 47: 2751-8.
    • (2009) J Clin Microbiol , vol.47 , pp. 2751-2758
    • Cavaco, L.M.1    Aarestrup, F.M.2
  • 21
    • 67651097670 scopus 로고    scopus 로고
    • Vitek2 system: a reliable tool to detect qnr determinants in Enterobacteriaceae without quinolone resistance-determining region modifications
    • Corvec S, Cremet L, Reynaud A et al. Vitek2 system: a reliable tool to detect qnr determinants in Enterobacteriaceae without quinolone resistance-determining region modifications. Diagn Microbiol Infect Dis 2009; 64: 455-7.
    • (2009) Diagn Microbiol Infect Dis , vol.64 , pp. 455-457
    • Corvec, S.1    Cremet, L.2    Reynaud, A.3
  • 22
    • 84885390721 scopus 로고    scopus 로고
    • Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae
    • Lupo A, Papp-Wallace KM, Sendi P et al. Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae. Diagn Microbiol Infect Dis 2013; 77: 179-94.
    • (2013) Diagn Microbiol Infect Dis , vol.77 , pp. 179-194
    • Lupo, A.1    Papp-Wallace, K.M.2    Sendi, P.3
  • 23
    • 80052194687 scopus 로고    scopus 로고
    • Evaluation of three automated systems for susceptibility testing of Enterobacteria containing qnrB, qnrS, and/or aac(6')-Ib-cr
    • Calvo J, Cano ME, Pitart C et al. Evaluation of three automated systems for susceptibility testing of Enterobacteria containing qnrB, qnrS, and/or aac(6')-Ib-cr. J Clin Microbiol 2011; 49: 3343-5.
    • (2011) J Clin Microbiol , vol.49 , pp. 3343-3345
    • Calvo, J.1    Cano, M.E.2    Pitart, C.3
  • 24
    • 17744374282 scopus 로고    scopus 로고
    • Evaluation of antimicrobial susceptibility of bacteria containing the qnr gene and FOX-5 β-lactamase by four automated systems
    • Rodriguez-Martinez JM, Conejo MC, Martinez-Martinez L et al. Evaluation of antimicrobial susceptibility of bacteria containing the qnr gene and FOX-5 β-lactamase by four automated systems. Clin Microbiol Infect 2005; 11: 402-4.
    • (2005) Clin Microbiol Infect , vol.11 , pp. 402-404
    • Rodriguez-Martinez, J.M.1    Conejo, M.C.2    Martinez-Martinez, L.3
  • 25
    • 45249123438 scopus 로고    scopus 로고
    • Activity of ciprofloxacin and levofloxacin in experimental pneumonia caused by Klebsiella pneumoniae deficient in porins, expressing active efflux and producing QnrA1
    • Rodriguez-Martinez JM, Pichardo C, Garcia I et al. Activity of ciprofloxacin and levofloxacin in experimental pneumonia caused by Klebsiella pneumoniae deficient in porins, expressing active efflux and producing QnrA1. Clin Microbiol Infect 2008; 14: 691-7.
    • (2008) Clin Microbiol Infect , vol.14 , pp. 691-697
    • Rodriguez-Martinez, J.M.1    Pichardo, C.2    Garcia, I.3
  • 26
    • 84887481649 scopus 로고    scopus 로고
    • Ciprofloxacin treatment failure in a murine model of pyelonephritis due to an AAC(6')-Ib-cr-producing Escherichia coli strain susceptible to ciprofloxacin in vitro
    • Guillard T, Cambau E, Chau F et al. Ciprofloxacin treatment failure in a murine model of pyelonephritis due to an AAC(6')-Ib-cr-producing Escherichia coli strain susceptible to ciprofloxacin in vitro. Antimicrob Agents Chemother 2013; 57: 5830-5.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5830-5835
    • Guillard, T.1    Cambau, E.2    Chau, F.3
  • 27
    • 84856070801 scopus 로고    scopus 로고
    • Changes in ciprofloxacin resistance levels in Enterobacter aerogenes isolates associated with variable expression of the aac(6')-Ib-cr gene
    • Ruiz E, Ocampo-Sosa AA, Alcoba-Florez J et al. Changes in ciprofloxacin resistance levels in Enterobacter aerogenes isolates associated with variable expression of the aac(6')-Ib-cr gene. Antimicrob Agents Chemother 2012; 56: 1097-100.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1097-1100
    • Ruiz, E.1    Ocampo-Sosa, A.A.2    Alcoba-Florez, J.3
  • 28
    • 65749099555 scopus 로고    scopus 로고
    • Plasmid-mediated quinolone resistance among enterobacteria with reduced susceptibility or resistance to ciprofloxacin but susceptible to nalidixic acid
    • Chicago, IL. Abstract C2-152. American Society for Microbiology, Washington, DC, USA
    • Cano ME, Calvo J, Agüero J et al. Plasmid-mediated quinolone resistance among enterobacteria with reduced susceptibility or resistance to ciprofloxacin but susceptible to nalidixic acid. In: Abstracts of the Forty-seventh Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 2007. Abstract C2-152, p. 103. American Society for Microbiology, Washington, DC, USA.
    • (2007) Abstracts of the Forty-seventh Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 103
    • Cano, M.E.1    Calvo, J.2    Agüero, J.3
  • 29
    • 84858690979 scopus 로고    scopus 로고
    • qnr, aac(6')-Ib-cr and qepA genes in Escherichia coli and Klebsiella spp.: Genetic environments and plasmid and chromosomal location
    • Ruiz E, Saenz Y, Zarazaga M et al. qnr, aac(6')-Ib-cr and qepA genes in Escherichia coli and Klebsiella spp.: Genetic environments and plasmid and chromosomal location. J Antimicrob Chemother 2012; 67: 886-97.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 886-897
    • Ruiz, E.1    Saenz, Y.2    Zarazaga, M.3
  • 30
    • 0030045364 scopus 로고    scopus 로고
    • In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins
    • Martinez-Martinez L, Hernandez-Alles S, Alberti S et al. In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins. Antimicrob Agents Chemother 1996; 40: 342-8.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 342-348
    • Martinez-Martinez, L.1    Hernandez-Alles, S.2    Alberti, S.3
  • 31
    • 0344863188 scopus 로고    scopus 로고
    • Energy-dependent accumulation of fluoroquinolones in quinolone-resistant Klebsiella pneumoniae strains
    • Martinez-Martinez L, Garcia I, Ballesta S et al. Energy-dependent accumulation of fluoroquinolones in quinolone-resistant Klebsiella pneumoniae strains. Antimicrob Agents Chemother 1998; 42: 1850-2.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1850-1852
    • Martinez-Martinez, L.1    Garcia, I.2    Ballesta, S.3
  • 32
    • 84879414758 scopus 로고    scopus 로고
    • Escherichia coli O25b:H4/ ST131 are prevalent in Spain and are often not associated with ESBL or quinolone resistance
    • Lopez-Cerero L, Bellido MM, Serrano L et al. Escherichia coli O25b:H4/ ST131 are prevalent in Spain and are often not associated with ESBL or quinolone resistance. Enferm Infecc Microbiol Clin 2013; 31: 385-8.
    • (2013) Enferm Infecc Microbiol Clin , vol.31 , pp. 385-388
    • Lopez-Cerero, L.1    Bellido, M.M.2    Serrano, L.3
  • 33
    • 0004155795 scopus 로고    scopus 로고
    • Verification and Validation of Procedures in the Clinical Microbiology Laboratory
    • McCurdy BW, ed. Washington, DC: American Society for Microbiology
    • Elder BL, Hansen SA, Kellogg JA et al. Verification and Validation of Procedures in the Clinical Microbiology Laboratory. In: McCurdy BW, ed. CUMITECH: Cumulative Techniques and Procedures in Clinical Microbiology. Washington, DC: American Society for Microbiology, 1997.
    • (1997) CUMITECH: Cumulative Techniques and Procedures in Clinical Microbiology
    • Elder, B.L.1    Hansen, S.A.2    Kellogg, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.