Vitek2® system: a reliable tool to detect qnr determinants in Enterobacteriaceae without quinolone resistance-determining region modifications

Diagnostic Microbiology and Infectious Disease

Volumn 64, Issue 4, 2009, Pages 455-457

  Corvec, Stéphane ^a,b   Crémet, Lise ^a   Reynaud, Alain ^a,b   Lepelletier, Didier ^a,b   Caroff, Nathalie ^a,b  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE NANTES   (France)

Author keywords

Detection; Enterobacteriaceae; qnr; Vitek2

Indexed keywords

BACTERIAL PROTEIN; CIPROFLOXACIN; NALIDIXIC ACID; NORFLOXACIN; OFLOXACIN; PROTEIN QNR; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL DNA; QUINOLONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIUM ISOLATE; CONTROLLED STUDY; ENTEROBACTERIACEAE; GENE IDENTIFICATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RELIABILITY; DNA FINGERPRINTING; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METHODOLOGY; MICROBIOLOGICAL EXAMINATION;

ANTI-BACTERIAL AGENTS; DNA FINGERPRINTING; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ENTEROBACTERIACEAE; HUMANS; MICROBIAL SENSITIVITY TESTS; QUINOLONES;

EID: 67651097670     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2009.03.026     Document Type: Article

References (11)

1. Cattoir V., Poirel L., Rotimi V., Soussy C.J., and Nordmann P. Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J. Antimicrob. Chemother. 60 (2007) 394-397
2. Communiqué de l'antibiogramme de la Société Française de Microbiologie CA-SFM (2006). http://www.sfm.asso.fr/publi/general.php?pa=5
3. Lavigne J.P., Marchandin H., Delmas J., Bouziges N., Lecaillon E., Cavalie L., Jean-Pierre H., Bonnet R., and Sotto A. qnrA in CTX-M-producing Escherichia coli isolates from France. Antimicrob. Agents Chemother. 50 (2006) 4224-4228
4. Murray A., Mather H., Coia J.E., and Brown D.J. Plasmid-mediated quinolone resistance in nalidixic-acid-susceptible strains of Salmonella enterica isolated in Scotland. J. Antimicrob. Chemother. 62 (2008) 1153-1155
5. Poirel L., Leviandier C., and Nordmann P. Prevalence and genetic analysis of plasmid-mediated quinolone resistance determinants QnrA and QnrS in Enterobacteriaceae isolates from a French university hospital. Antimicrob. Agents Chemother. 50 (2006) 3992-3997
6. Poirel L., Cattoir V., and Nordmann P. Is plasmid-mediated quinolone resistance a clinically significant problem?. Clin. Microbiol. Infect. 14 (2008) 295-297
7. Robicsek A., Jacoby G.A., and Hooper D.C. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect. Dis. 6 (2006) 629-640
8. Ruiz J. Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection. J. Antimicrob. Chemother. 51 (2003) 1109-1117
9. Wang M.H., Xu X., Wu S., Zhu D., and Wang M.G. A new plasmid-mediated gene for quinolone resistance, qnrC. Abstract [O207], ECCMID,19-22 April (2008), Barcelona, Spain
10. Weigel L.M., Steward C.D., and Tenover F. gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae. Antimicrob. Agents Chemother. 42 (1998) 2661-2667
11. Yamane K., Wachino J., Suzuki S., Kimura K., Shibata N., Kato H., Shibayama K., Konda T., and Arakawa Y. New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrob. Agents Chemother. 51 (2007) 3354-3360