Preformed chitosan cryogel-biphasic calcium phosphate: A potential injectable biocomposite for pathologic fracture

Journal of Biomaterials Applications

Volumn 30, Issue 2, 2015, Pages 182-192

  Abueva, Celine D G ^a   Padalhin, Andrew R ^a   Min, Young Ki ^a   Lee, Byong Taek ^a  

^a Soonchunhyang University College of Medicine   (South Korea)

Author keywords

bone filler; bone tissue engineering; calcium phosphate; chitosan; Cryogel; injectable biocomposite

Indexed keywords

BIOCOMPATIBILITY; CALCIUM PHOSPHATE; CHITOSAN; COMPOSITE MATERIALS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FRACTURE; NEEDLES; PATHOLOGY; PHYSICOCHEMICAL PROPERTIES; PROTEINS; SCANNING ELECTRON MICROSCOPY; TISSUE; X RAY POWDER DIFFRACTION;

BIO-COMPOSITES; BIOCOMPOSITE SYSTEMS; BIPHASIC CALCIUM PHOSPHATES; BONE FILLING MATERIALS; BONE TISSUE ENGINEERING; BONE-FILLERS; CRYOGELS; INJECTABLE SCAFFOLDS;

SCAFFOLDS (BIOLOGY);

BIOMATERIAL; CALCIUM PHOSPHATE; CHITOSAN; CRYOGEL; PROTEIN;

ADSORPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CELL ENCAPSULATION; CELL INFILTRATION; CELL INTERACTION; CONTROLLED STUDY; CRYOGEL; HISTOLOGY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INJECTION; MORPHOLOGY; NEEDLE; NONHUMAN; PATHOLOGIC FRACTURE; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SKIN; X RAY DIFFRACTION; 3T3 CELL LINE; ANIMAL; CHEMISTRY; FRACTURES, BONE; MALE; MOUSE; SPRAGUE DAWLEY RAT;

3T3 CELLS; ANIMALS; BIOCOMPATIBLE MATERIALS; CALCIUM PHOSPHATES; CHITOSAN; CRYOGELS; FRACTURES, BONE; MALE; MICE; MICROSCOPY, ELECTRON, SCANNING; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 84936888022     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328215577892     Document Type: Article

References (31)

1. Klouda L, Mikos AG,. Thermoresponsive hydrogels in biomedical applications. Eur J Pharm Biopharm 2008; 68: 34-45.
2. Yang J-A, Yeom J, Hwang BW,. In situ-forming injectable hydrogels for regenerative medicine. Progr Polym Sci 2014; 39: 1973-1986.
3. Bencherif SA, Sands RW, Bhatta D,. Injectable preformed scaffolds with shape-memory properties. Proceedings of the National Academy of Sciences 2012.
4. Bhattarai N, Gunn J, Zhang M,. Chitosan-based hydrogels for controlled, localized drug delivery. Adv Drug Delivery Rev 2010; 62: 83-99.
5. Mekhail M, Tabrizian M,. Injectable chitosan-based scaffolds in regenerative medicine and their clinical translatability. Adv Healthcare Mater 2014; 3: 1529-1545.
6. Amsden BG, Sukarto A, Knight DK,. Methacrylated glycol chitosan as a photopolymerizable biomaterial. Biomacromolecules 2007; 8: 3758-3766.
7. Chenite A, Chaput C, Wang D,. Novel injectable neutral solutions of chitosan form biodegradable gels in situ. Biomaterials 2000; 21: 2155-2161.
8. Takei T, Nakahara H, Ijima H,. Synthesis of a chitosan derivative soluble at neutral pH and gellable by freeze-thawing, and its application in wound care. Acta Biomater 2012; 8: 686-693.
9. Koshy ST, Ferrante TC, Lewin SA,. Injectable, porous, and cell-responsive gelatin cryogels. Biomaterials 2014; 35: 2477-2487.
10. Martinez YN, Pinuel L, Castro GR,. Polyvinyl alcohol-pectin cryogel films for controlled release of enrofloxacin. Appl Biochem Biotechnol 2012; 167: 1421-1429.
11. Pignolo RJKMAS. Fractures in the elderly a guide to practical management, New York: Humana Press, 2011.
12. Guarneri V, Conte PF,. The curability of breast cancer and the treatment of advanced disease. Eur J Nucl Med Mol Imaging 2004; 31: 24.
13. Lopez-Heredia MA, Bernard Kamphuis GJ, Thüne PC,. An injectable calcium phosphate cement for the local delivery of paclitaxel to bone. Biomaterials 2011; 32: 5411-5416.
14. Prolo DJ, Rodrigo JJ,. Contemporary bone graft physiology and surgery. Clin Orthop Relat Res 1985; 200: 322-342.
15. Bajammal SS, Zlowodzki M, Lelwica A,. The use of calcium phosphate bone cement in fracture treatment. A meta-analysis of randomized trials. J Bone Joint Surg Am 2008; 90: 1186-1196.
16. Comuzzi L, Ooms E, Jansen JA,. Injectable calcium phosphate cement as a filler for bone defects around oral implants: an experimental study in goats. Clin Oral Implants Res 2002; 13: 304-311.
17. Félix Lanao RP, Leeuwenburgh SCG, Wolke JGC,. Bone response to fast-degrading, injectable calcium phosphate cements containing PLGA microparticles. Biomaterials 2011; 32: 8839-8847.
18. LeGeros RZ, Lin S, Rohanizadeh R,. Biphasic calcium phosphate bioceramics: preparation, properties and applications. J Mater Sci Mater Med 2003; 14: 201-209.
19. Seol YJ, Lee JY, Park YJ,. Chitosan sponges as tissue engineering scaffolds for bone formation. Biotechnol Lett 2004; 26: 1037-1041.
20. Carey LE, Xu HH, Simon CG Jr,. Premixed rapid-setting calcium phosphate composites for bone repair. Biomaterials 2005; 26: 5002-5014.
21. Liu H, Li H, Cheng W,. Novel injectable calcium phosphate/chitosan composites for bone substitute materials. Acta Biomater 2006; 2: 557-5565.
22. Mukherjee DP, Tunkle AS, Roberts RA,. An animal evaluation of a paste of chitosan glutamate and hydroxyapatite as a synthetic bone graft material. J Biomed Mater Res B Appl Biomater 2003; 67B: 603-609.
23. Park DJ, Choi BH, Zhu SJ,. Injectable bone using chitosan-alginate gel/mesenchymal stem cells/BMP-2 composites. J Craniomaxillofac Surg 2005; 33: 50-54.
24. Lee B-T, Youn M-H, Paul RK,. In situ synthesis of spherical BCP nanopowders by microwave assisted process. Mater Chem Phys 2007; 104: 249-253.
25. Baker S, Wiesmann WP, Ryan S, et al. Methods of making a chitosan product having an ultra-low endotoxin concentration and the ultra-low endotoxin chitosan product derived therefrom and method of accurately determining inflammatory and anti-inflammatory cellular response to such materials. Google Patents, 2008.
26. Gan Q, Wang T,. Chitosan nanoparticle as protein delivery carrier-systematic examination of fabrication conditions for efficient loading and release. Coll Surf B Biointerf 2007; 59: 24-34.
27. TenHuisen KS, Brown PW,. Formation of calcium-deficient hydroxyapatite from alpha-tricalcium phosphate. Biomaterials 1998; 19: 2209-2217.
28. Collier TO, Jenney CR, DeFife KM,. Protein adsorption on chemically modified surfaces. Biomed Sci Instrum 1997; 33: 178-183.
29. Wang K, Zhou C, Hong Y,. A review of protein adsorption on bioceramics. Interf Focus 2012; 2: 259-277.
30. Ohta K, Monma H, Takahashi S,. Adsorption characteristics of proteins on calcium phosphates using liquid chromatography. J Biomed Mater Res 2001; 55: 409-414.
31. Ueno H, Yamada H, Tanaka I,. Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs. Biomaterials 1999; 20: 1407-1414.