Impaired endogenous fibrinolytic capacity in prehypertensive men

Journal of Human Hypertension

Volumn 29, Issue 8, 2015, Pages 468-472

  Diehl, K J ^a   Weil, B R ^a   Greiner, J J ^a   Wright, K P ^a   Stauffer, B L ^a,b,c   DeSouza, C A ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c DENVER HEALTH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; NITROPRUSSIDE SODIUM; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; ARTICLE; BODY COMPOSITION; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EXERCISE TEST; FIBRINOLYSIS; HUMAN; HUMAN TISSUE; HYPERTENSION; IN VIVO STUDY; MALE; PREHYPERTENSION; SYSTOLIC BLOOD PRESSURE; TREADMILL EXERCISE; CIRCULATION; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

BLOOD CIRCULATION; BRADYKININ; ENDOTHELIUM, VASCULAR; FIBRINOLYSIS; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; NITROPRUSSIDE; PREHYPERTENSION; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84936846840     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/jhh.2014.120     Document Type: Article

References (38)

1. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics-2013 update: a report from the American Heart Association. Circulation 2013; 127(1): e6-e245.
2. Huang Y, Su L, Cai X, Mai W, Wang S, Hu Y, et al. Association of all-cause and cardiovascular mortality with prehypertension: a meta-analysis. Am Heart J 2014; 167(2): 160-168 e1.
3. Vasan RS, Larson MG, Leip EP, Evans JC, O'Donnell CJ, Kannel WB, et al. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 2001; 345(18): 1291-1297.
4. Williams B. The year in hypertension. J Am Coll Cardiol 2009; 55(1): 65-73.
5. Elliott WJ, Black HR. Prehypertension. Nat Clin Pract Cardiovasc Med 2007; 4(10): 538-548.
6. Caballero AE. Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease. Obes Res 2003; 11(11): 1278-1289.
7. Quyyumi A. Endothelial function in health and disease: new insights into the genesis of cardiovascular disease. Am J Med 1998; 105: 32S-39S.
8. Van Guilder GP, Hoetzer GL, Smith DT, Irmiger HM, Greiner JJ, Stauffer BL, et al. Endothelial t-PA release is impaired in overweight and obese adults but can be improved with regular aerobic exercise. Am J Physiol Endocrinol Metab 2005; 289 (5): E807-E813.
9. Parmer R, Mahata M, Mahata S, Sebald M, O'Connor D, Miles L. Tissue plasminogen activator (t-PA) is targeted to the regulated secretory pathway. J Biolo Chem 1997; 272: 1976-1982.
10. van den Eijnden-Schrauwen Y, Kooistra T, de Vries RE, Emeis JJ. Studies on the acute release of tissue-type plasminogen activator from human endothelial cells in vitro and in rats in vivo: evidence for a dynamic storage pool. Blood 1995; 85 (12): 3510-3517.
11. Lucking AJ, Gibson KR, Paterson EE, Faratian D, Ludlam CA, Boon NA, et al. Endogenous tissue plasminogen activator enhances fibrinolysis and limits thrombus formation in a clinical model of thrombosis. Arterioscler Thromb Vasc Biol 2013; 33(5): 1105-1111.
12. Robinson SD, Ludlam CA, Boon NA, Newby DE. Endothelial fibrinolytic capacity predicts future adverse cardiovascular events in patients with coronary heart disease. Arterioscler Thromb Vasc Biol 2007; 27(7): 1651-1656.
13. Newby DE, McLeod AL, Uren NG, Flint L, Ludlam CA, Webb DJ, et al. Impaired coronary tissue plasminogen activator release is associated with coronary atherosclerosis and cigarette smoking. Circulation 2001; 103(15): 1936-1941.
14. Hrafnkelsdottir T, Wall U, Jern C, Jern S. Impaired capacity for endogenous fibrinolysis in essential hypertension. Lancet 1998; 352(9140): 1597-1598.
15. Chobanian A, Bakris G, Black H, Cushman W, Green L, Izzo J, et al. The Seventh Report Of The Joint National Committe On Prevention, Detection, Evaluation, And Treatment Of High Blood Pressure. The JNC 7 report. JAMA 2003; 289: 2560-2572.
16. Lohman T, Roche A, Mortorell R. Athropometric Standardization Reference Manual. Human Kinetics: Champaign, IL, USA, 1988.
17. Van Guilder GP, Hoetzer GL, Greiner JJ, Stauffer BL, DeSouza CA. Acute and chronic effects of vitamin C on endothelial fibrinolytic function in overweight and obese adult humans. J Physiol 2008; 586(14): 3525-3535.
18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28 (7): 412-419.
19. Jern S, Wall U, Bergbrant A, Selin-Sjogren L, Jern C. Endothelium-dependent vasodilation and tissue-type plasminogen activator release in borderline hypertension. Arterioscler Thromb Vasc Biol 1997; 17(12): 3376-3383.
20. Chaplin H, Mollison P. Correction of plasma trapped in the red cell column of hematocrit. Blood 1952; 7: 1227-1238.
21. Macko R, Ameriso S, Gruber A, Griffin J, Fernandez J, Brandt R, et al. Impairments of the protein C system and fibrinolysis in infection-associated stroke. Stroke 1996; 27: 2005-2011.
22. Qureshi AI, Suri MF, Kirmani JF, Divani AA, Mohammad Y. Is prehypertension a risk factor for cardiovascular diseases? Stroke 2005; 36(9): 1859-1863.
23. Liszka HA, Mainous AG 3rd, King DE, Everett CJ, Egan BM. Prehypertension and cardiovascular morbidity. Ann Fam Med 2005; 3(4): 294-299.
24. Hsia J, Margolis KL, Eaton CB, Wenger NK, Allison M, Wu L, et al. Prehypertension and cardiovascular disease risk in the Women's Health Initiative. Circulation 2007; 115(7): 855-860.
25. Vasan RS, Larson MG, Leip EP, Evans JC, O'Donnell CJ, Kannel WB, et al. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 2001; 345(18): 1291-1297.
26. Baldinger B, Schwarz C, Jaggy C. Cardiovascular risk factors, BMI and mortality in a cohort of Swiss males (1976-2001) with high-sum-assured life insurance cover. J Insur Med 2006; 38(1): 44-53.
27. Weil BR, Westby CM, Greiner JJ, Stauffer BL, DeSouza CA. Elevated endothelin-1 vasoconstrictor tone in prehypertensive adults. Can J Cardiol 2012; 28(3): 347-353.
28. Weil BR, Stauffer BL, Greiner JJ, DeSouza CA. Prehypertension Is Associated With Impaired Nitric Oxide-Mediated Endothelium-Dependent Vasodilation in Sedentary Adults. Am J Hypertens 2009; 24(9): 976-981.
29. Giannotti G, Doerries C, Mocharla PS, Mueller MF, Bahlmann FH, Horvàth T, et al. Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: relation to endothelial dysfunction. Hypertension 2010; 55(6): 1389-1397.
30. Carmeliet P, Schoonjans L, Kieckens L, Ream B, Degan J, Bronson R, et al. Physiological consequences of loss of plasminogen activator gene function in mice. Nature 1994; 368: 419-424.
31. Christie P, Edelberg J, Picard M, Foulkes A, Mamuya W, Weiler-Guettler H, et al. A murine model of myocardial microvascular thrombosis. J Clin Invest 1999; 10: 533-539.
32. Newby DE, Wright RA, Labinjoh C, Ludlam CA, Fox KAA, Boon NA, et al. Endothelial Dysfunction, Impaired Endogenous Fibrinolysis, and Cigarette Smoking. Circulation 1999; 99(11): 1411-1415.
33. Dikalov SI, Ungvari Z. Role of mitochondrial oxidative stress in hypertension. Am J Physiol Heart Circ Physiol 2013; 305(10): H1417-H1427.
34. Lip G, Edmunds E, Nuttall SL, Landray MJ, Blann AD, Beevers DG. Oxidative stress in malignant and non-malignant phase hypertension. J Human Hypertens 2002; 16 (5): 333-336.
35. Harrison DG, Gongora MC. Oxidative stress and hypertension. Med Clin North Am 2009; 93(3): 621-635.
36. Chrysohoou C, Panagiotakos DB, Pitsavos C, Skoumas J, Economou M, Papadimitriou L, et al. The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: the ATTICA study. Atherosclerosis 2007; 192(1): 169-176.
37. Kaehler J, Koeke K, Karstens M, Schneppenheim R, Meinertz T, Heitzer T. Impaired capacity for acute endogenous fibrinolysis in smokers is restored by ascorbic acid. Free Radical Bio Med 2008; 44(3): 315-321.
38. Stauffer BL, Hoetzer GL, Van Guilder GP, Smith DT, DeSouza CA. Gender differences in endothelial tissue-type plasminogen activator release in middle-aged adults. J Am Coll Cardiol 2005; 45(9): 1547-1549.