Hippo component TAZ functions as a co-repressor and negatively regulates ΔNp63 transcription through TEA domain (TEAD) transcription factor

Journal of Biological Chemistry

Volumn 290, Issue 27, 2015, Pages 16906-16917

  Valencia Sama, Ivette ^a   Zhao, Yulei ^a   Lai, Dulcie ^a   Van Rensburg, Helena J Janse ^a   Hao, Yawei ^a   Yang, Xiaolong ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BINS; BIOLOGICAL SYSTEMS; DRUG THERAPY; GENE EXPRESSION; GENES; MOBILE SECURITY; TRANSCRIPTION FACTORS;

BIOLOGICAL FUNCTIONS; GENE EXPRESSION PROFILES; LUNG EPITHELIAL CELLS; MOLECULAR MECHANISM; PROMOTER ACTIVITIES; PROTEIN EXPRESSIONS; TRANSCRIPTIONAL CO-ACTIVATORS; TRANSCRIPTIONAL TARGETS;

TRANSCRIPTION;

CHEMOKINE; CYTOKINE; HISTONE; PROTEIN P53; PROTEIN P63; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TEAD; TRANSCRIPTION FACTOR TTF1; UNCLASSIFIED DRUG; COREPRESSOR PROTEIN; DNA BINDING PROTEIN; HIPPO PROTEIN, HUMAN; MUSCLE PROTEIN; NUCLEAR PROTEIN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; TEAD1 PROTEIN, HUMAN; TEAD2 PROTEIN, HUMAN; TEAD3 PROTEIN, HUMAN; TEAD4 PROTEIN, HUMAN; TP63 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; WWTR1 PROTEIN, HUMAN;

ACTIN POLYMERIZATION; APOPTOSIS; ARTICLE; BINDING SITE; BIOLOGICAL FUNCTIONS; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; EPITHELIUM CELL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC CONSERVATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; METASTASIS; MOLECULAR MECHANICS; MULTIGENE FAMILY; ORGAN SIZE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REPRESSOR GENE; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; UPREGULATION; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NEOPLASM; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

CELL LINE, TUMOR; CO-REPRESSOR PROTEINS; DNA-BINDING PROTEINS; DOWN-REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE PROTEINS; NEOPLASMS; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84936803669     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.642363     Document Type: Article

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