2′-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF

Nucleic Acids Research

Volumn 43, Issue 9, 2015, Pages 4569-4578

  Shen, Wen ^a   Liang, Xue Hai ^a   Sun, Hong ^a   Crooke, Stanley T ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FLUORINE; NONO PROTEIN, HUMAN; NUCLEAR MATRIX PROTEIN; NUCLEAR PROTEIN; OCTAMER TRANSCRIPTION FACTOR; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; P54NRB PROTEIN, MOUSE; PSPC1 PROTEIN, HUMAN; PTB-ASSOCIATED SPLICING FACTOR; RNA BINDING PROTEIN;

ANIMAL; CHEMISTRY; DNA DAMAGE; HELA CELL LINE; HUMAN; METABOLISM; MOUSE; PROTEIN STABILITY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; DNA DAMAGE; FLUORINE; HELA CELLS; HUMANS; MICE; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTORS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; PROTEIN STABILITY; RNA-BINDING PROTEINS;

EID: 84936792294     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv298     Document Type: Article

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