Liver fat deposition and mitochondrial dysfunction in morbid obesity: An approach combining metabolomics with liver imaging and histology

World Journal of Gastroenterology

Volumn 21, Issue 24, 2015, Pages 7529-7544

  Calvo, Nahum ^a   Beltrán Debón, Raúl ^a   Rodríguez Gallego, Esther ^a   Hernández Aguilera, Anna ^a   Guirro, Maria ^a   Mariné Casadó, Roger ^a   Millá, Lidón ^a   Alegret, Josep M ^a   Sabench, Fàtima ^b   Del Castillo, Daniel ^b   Vinaixa, María ^a   Rodríguez, Miguel Àngel ^a   Correig, Xavier ^a   García Álvarez, Roberto ^c   Menendez, Javier A ^d   Camps, Jordi ^a   Joven, Jorge ^a  

^a INSTITUT D INVESTIGACIÓ SANITÀRIA PERE VIRGILI IISPV   (Spain)

^b HOSPITAL UNIVERSITARI SANT JOAN DE REUS   (Spain)

^c GE HEALTHCARE   (France)

^d GIRONA BIOMEDICAL RESEARCH INSTITUTE IDIBGI   (Spain)

Author keywords

Fatty liver disease; Lipids; Magnetic resonance imaging; Magnetic resonance spectroscopy; Metabolomics; Mitochondrial function; Morbid obesity; Non alcoholic fatty liver disease; Non alcoholic steatohepatitis

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID; BIOLOGICAL MARKER; CHOLESTEROL; DIACYLGLYCEROL; DOCOSAHEXAENOIC ACID; FUMARIC ACID; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLYCOGEN; ICOSAPENTAENOIC ACID; LACTIC ACID; LINOLEIC ACID; LIPID; LYSOPHOSPHATIDYLCHOLINE; MONOACYLGLYCEROL; MONOUNSATURATED FATTY ACID; OLEIC ACID; OMEGA 3 FATTY ACID; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PLASMALOGEN; POLYUNSATURATED FATTY ACID; PYRUVIC ACID; SPHINGOMYELIN; TRIACYLGLYCEROL; URACIL; URIDINE DIPHOSPHATE GLUCOSE;

ADIPOSE TISSUE; ADULT; ARTICLE; BARIATRIC SURGERY; BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FATTY ACID BLOOD LEVEL; FEMALE; FOLLOW UP; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEPATITIS; HEPATOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LAPAROSCOPIC SURGERY; LIPID LIVER LEVEL; LIPID METABOLISM; LIPID STORAGE; LIVER BIOPSY; LIVER MITOCHONDRION; MALE; METABOLOMICS; MORBID OBESITY; NONALCOHOLIC FATTY LIVER; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBSERVATIONAL STUDY; OXIDATIVE STRESS; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PROSPECTIVE STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; SLEEVE GASTRECTOMY; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION; BIOPSY; BLOOD; COMPLICATION; LIVER; METABOLISM; MIDDLE AGED; MITOCHONDRIAL DISEASES; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY, MORBID; PATHOLOGY; PREDICTIVE VALUE; PROCEDURES; REMISSION; REPRODUCIBILITY; SEVERITY OF ILLNESS INDEX; SPAIN; TIME FACTOR; TREATMENT OUTCOME;

ADULT; BARIATRIC SURGERY; BIOMARKERS; BIOPSY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LIPIDS; LIVER; MAGNETIC RESONANCE IMAGING; MALE; METABOLOMICS; MIDDLE AGED; MITOCHONDRIA, LIVER; MITOCHONDRIAL DISEASES; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY, MORBID; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTON MAGNETIC RESONANCE SPECTROSCOPY; REMISSION INDUCTION; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; SPAIN; TIME FACTORS; TREATMENT OUTCOME;

EID: 84936773835     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i24.7529     Document Type: Article

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