Effect of delayed cord clamping on neurodevelopment at 4 years of age: A randomized clinical trial

JAMA Pediatrics

Volumn 169, Issue 7, 2015, Pages 631-638

  Andersson, Ola ^a   Lindquist, Barbro ^b   Lindgren, Magnus ^c   Stjernqvist, Karin ^c   Domellöf, Magnus ^d   Hellström Westas, Lena ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Hospital of Halland   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGES AND STAGES QUESTIONNAIRE THIRD EDITION; ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GYNECOLOGIC SURGERY; HIGH RISK PREGNANCY; HUMAN; INTELLIGENCE QUOTIENT; INVESTIGATIVE PROCEDURES; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MOVEMENT ASSESSMENT BATTERY FOR CHILDREN; NERVE CELL DIFFERENTIATION; NEWBORN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PSYCHOLOGIST; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; STRENGTHS AND DIFFICULTIES QUESTIONNAIRE; UMBILICAL CORD; UMBILICAL CORD CLAMPING; WECHSLER INTELLIGENCE SCALE; CHILD; CHILD DEVELOPMENT; DELIVERY; GROWTH, DEVELOPMENT AND AGING; INFANT; LIGATION; NERVOUS SYSTEM; PREGNANCY; PRESCHOOL CHILD; PROCEDURES; SURGERY; SWEDEN; TIME;

CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; CONSTRICTION; DELIVERY, OBSTETRIC; FEMALE; HUMANS; INFANT; MALE; NERVOUS SYSTEM; PREGNANCY; SWEDEN; TIME FACTORS; UMBILICAL CORD;

EID: 84936772531     PISSN: 21686203     EISSN: 21686211     Source Type: Journal    
DOI: 10.1001/jamapediatrics.2015.0358     Document Type: Article

References (30)

1. Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev. 2006;64(5, pt 2):S34-S43.
2. Radlowski EC, Johnson RW. Perinatal iron deficiency and neurocognitive development. Front Hum Neurosci. 2013;7:585.
3. Domellöf M. Iron requirements in infancy. Ann Nutr Metab. 2011;59(1):59-63.
4. de Benoist B, McLean E, Egli I, Cogswell M. Worldwide Prevalence of Anaemia 1993-2005: WHO Global Database on Anaemia. Geneva, Switzerland: World Health Organization; 2008.
5. Domellöf M, Braegger C, Campoy C, et al; ESPGHAN Committee on Nutrition. Iron requirements of infants and toddlers. J Pediatr Gastroenterol Nutr. 2014;58(1):119-129.
6. Szajewska H, Ruszczynski M, Chmielewska A. Effects of iron supplementation in nonanemic pregnant women, infants, and young children on the mental performance and psychomotor development of children: A systematic review of randomized controlled trials. Am J Clin Nutr. 2010; 91(6):1684-1690.
7. Berglund SK, Westrup B, Hägglöf B, Hernell O, Domellöf M. Effects of iron supplementation of LBW infants on cognition and behavior at 3 years. Pediatrics. 2013;131(1):47-55.
8. Yao AC, Moinian M, Lind J. Distribution of blood between infant and placenta after birth. Lancet. 1969;2(7626):871-873.
9. Farrar D, Airey R, Law GR, Tuffnell D, Cattle B, Duley L. Measuring placental transfusion for term births: Weighing babies with cord intact. BJOG. 2011;118(1):70-75.
10. Yao AC, Lind J. Placental transfusion. AJDC. 1974; 127(1):128-141.
11. McDonald SJ, Middleton P, Dowswell T, Morris PS. Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Cochrane Database Syst Rev. 2013;7:CD004074.
12. Chaparro CM, Neufeld LM, Tena Alavez G, Eguia-Líz Cedillo R, Dewey KG. Effect of timing of umbilical cord clamping on iron status inMexican infants: A randomised controlled trial. Lancet. 2006;367(9527):1997-2004.
13. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press; 2001.
14. Andersson O, Hellström-Westas L, Andersson D, Domellöf M. Effect of delayed versus early umbilical cord clamping on neonatal outcomes and iron status at 4 months: A randomised controlled trial [published online November 15, 2011]. BMJ. 2011;343:d7157.
15. Committee on Obstetric Practice, American College of Obstetricians and Gynecologists. Committee Opinion No.543: Timing of umbilical cord clamping after birth. Obstet Gynecol. 2012;120 (6):1522-1526.
16. Wechsler D. Wechsler Preschool and Primary Scale of Intelligence (Swedish Version). Stockholm, Sweden: Pearson Assessment; 2005.
17. Henderson SE, Sugden DA, Barnett A. Movement Assessment Battery for Children, Second Edition (Swedish). Stockholm, Sweden: Pearson Assessment; 2007.
18. Lantz C, Melén K. Fine Motor Development at 1-7 Years of Age: An Evaluation and Correction of an Earlier Report [in Swedish]. Stockholm, Sweden: Stockholms läns landsting, Omsorgsnämnden; 1992.
19. Schneck CM, Henderson A. Descriptive analysis of the developmental progression of grip position for pencil and crayon control in nondysfunctional children. Am J Occup Ther. 1990;44(10):893-900.
20. Squires J, Twombly E, Bricker D, Potter L. ASQ-3 User's Guide. 3rd ed. Baltimore, MD: Brookes Publishing Co; 2009.
21. Goodman R. The extended version of the Strengths and Difficulties Questionnaire as a guide to child psychiatric caseness and consequent burden. J Child Psychol Psychiatry. 1999;40(5):791-799.
22. American Academy of Pediatrics. Scoring the informant-rated Strengths and Difficulties Questionnaire. https://brightfutures.aap.org/pdfs/Other%203/SDQ%20Scoring%20Instructions%20(Parent, %20Teacher).pdf. Accessed April 8, 2015.
23. Tamura T, Goldenberg RL, Hou J, et al. Cord serum ferritin concentrations and mental and psychomotor development of children at five years of age. J Pediatr. 2002;140(2):165-170.
24. Gunnarsson BS, Thorsdottir I, Palsson G, Gretarsson SJ. Iron status at 1 and 6 years versus developmental scores at 6 years in a well-nourished affluent population. Acta Paediatr. 2007;96(3): 391-395.
25. Andersson O, Domellöf M, Andersson D, Hellström-Westas L. Effect of delayed vs early umbilical cord clamping on iron status and neurodevelopment at age 12 months: A randomized clinical trial. JAMA Pediatr. 2014;168(6):547-554.
26. Tamura T, Hou J, Goldenberg RL, Johnston KE, Cliver SP. Gender difference in cord serum ferritin concentrations. Biol Neonate. 1999;75(6):343-349.
27. Domellöf M, Lönnerdal B, Dewey KG, Cohen RJ, Rivera LL, Hernell O. Sex differences in iron status during infancy. Pediatrics. 2002;110(3):545-552.
28. Yang Z, Lönnerdal B, Adu-Afarwuah S, et al. Prevalence and predictors of iron deficiency in fully breastfed infants at 6mo of age: comparison of data from 6 studies. Am J Clin Nutr. 2009;89(5): 1433-1440.
29. Mercer JS, Vohr BR, Erickson-Owens DA, Padbury JF, Oh W. Seven-month developmental outcomes of very low birth weight infants enrolled in a randomized controlled trial of delayed versus immediate cord clamping. J Perinatol. 2010;30(1): 11-16.
30. National Collaborating Centre for Women's and Children's Health. Intrapartum Care: Care of Healthy Women and Their Babies During Childbirth. London, England: RCOG Press; 2007.