Neoadjuvant FOLFOX 4 versus FOLFOX 4 with Cetuximab versus immediate surgery for high-risk stage II and III colon cancers: A multicentre randomised controlled phase II trial - the PRODIGE 22 - ECKINOXE trial

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Karoui, Mehdi ^a,b   Rullier, Anne ^c   Luciani, Alain ^d   Bonnetain, Franck ^e   Auriault, Marie Luce ^d   Sarran, Antony ^f   Monges, Geneviève ^f   Trillaud, Hervé ^g   Le Malicot, Karine ^b   Leroy, Karen ^d   Sobhani, Iradj ^d   Bardier, Armelle ^a   Moreau, Marie ^b   Brindel, Isabelle ^h   Seitz, Jean François ^b   Taieb, Julien ^b,i  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b Federation Francophone de Cancerologie Digestive FFCD Statistical Center   (France)

^c HÔPITAL PELLEGRIN   (France)

^d HENRI MONDOR HOSPITAL   (France)

^e UNIVERSITY HOSPITAL OF BESANÇON   (France)

^f INSTITUT PAOLI CALMETTES   (France)

^g HÔPITAL SAINT ANDRÉ   (France)

^h ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

ⁱ UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cetuximab; Colon cancer; FOLFOX; Locally advanced disease; Neoadjuvant chemotherapy; Randomized phase II trial

Indexed keywords

CETUXIMAB; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN; ANTINEOPLASTIC AGENT; PLATINUM COMPLEX;

ABDOMINAL RADIOGRAPHY; ADJUVANT THERAPY; ARTICLE; CANCER GRADING; CANCER REGRESSION; CANCER STAGING; COLON CANCER; COLON RESECTION; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; DRUG EFFICACY; DRUG SAFETY; FEASIBILITY STUDY; GENE MUTATION; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; INTERMETHOD COMPARISON; MORBIDITY; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; ONCOGENE RAS; PATIENT SELECTION; PERIOPERATIVE PERIOD; PHASE 2 CLINICAL TRIAL; POSTOPERATIVE CARE; PREVALENCE; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; RECURRENCE FREE SURVIVAL; SAMPLE SIZE; TREATMENT OUTCOME; TREATMENT RESPONSE; WILD TYPE; ADJUVANT CHEMOTHERAPY; CLINICAL TRIAL; COLONIC NEOPLASMS; NEOADJUVANT THERAPY; PATHOLOGY;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CETUXIMAB; CHEMOTHERAPY, ADJUVANT; COLONIC NEOPLASMS; FLUOROURACIL; HUMANS; LEUCOVORIN; NEOADJUVANT THERAPY; NEOPLASM STAGING; ORGANOPLATINUM COMPOUNDS;

EID: 84936772084     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1507-3     Document Type: Article

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