Parvalbumin-positive inhibitory interneurons oppose propagation but favor generation of focal epileptiform activity

Journal of Neuroscience

Volumn 35, Issue 26, 2015, Pages 9544-9557

  Sessolo, Michele ^a   Marcon, Iacopo ^a   Bovetti, Serena ^b   Losi, Gabriele ^a   Cammarota, Mario ^a   Ratto, Gian Michele ^c   Fellin, Tommaso ^b   Carmignoto, Giorgio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^c CNR   (Italy)

Author keywords

Channelrhodopsin 2; Cortex; Epileptiform activity; Optogenetics; Parvalbumin; Rebound spiking

Indexed keywords

CALCIUM; PARVALBUMIN; 4 AMINOBUTYRIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; CHANNELRHODOPSIN 2, MOUSE; N METHYLASPARTIC ACID; PHOTOPROTEIN; RHODOPSIN;

AFTERDISCHARGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ELECTROENCEPHALOGRAPHY PHASE SYNCHRONIZATION; ELECTROPHYSIOLOGY; EPILEPTIC DISCHARGE; FOCAL EPILEPSY; IMMUNOHISTOCHEMISTRY; LASER MICROSCOPY; MOUSE; NERVE CELL INHIBITION; NONHUMAN; OPTOGENETICS; PHOTOSTIMULATION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SPIKE WAVE; ACTION POTENTIAL; ANIMAL; BRAIN; CYTOLOGY; DRUG EFFECTS; FEMALE; GENETIC TRANSDUCTION; GENETICS; IN VITRO STUDY; INTERNEURON; MALE; METABOLISM; NEWBORN; PHYSIOLOGY; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; BRAIN; CALCIUM; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GAMMA-AMINOBUTYRIC ACID; IN VITRO TECHNIQUES; INTERNEURONS; LUMINESCENT PROTEINS; MALE; MICE; MICE, TRANSGENIC; N-METHYLASPARTATE; NEURAL INHIBITION; PARVALBUMINS; PHOTIC STIMULATION; PYRAMIDAL CELLS; RHODOPSIN; TRANSDUCTION, GENETIC;

EID: 84936139063     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5117-14.2015     Document Type: Article

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