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Volumn 7, Issue JUN, 2015, Pages

Duration-dependent effects of the BDNF Val66Met polymorphism on anodal tDCS induced motor cortex plasticity in older adults: A group and individual perspective

Author keywords

BDNF; Corticospinal excitability; Motor cortex; Older adults; Plasticity; Transcranial direct current stimulation (tDCS); Transcranial magnetic stimulation (TMS); Val66Met polymorphism

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; VALINE;

EID: 84936115921     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2015.00107     Document Type: Article
Times cited : (59)

References (47)
  • 1
    • 84897930952 scopus 로고    scopus 로고
    • Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction
    • Anastasia, A., Deinhardt, K., Chao, M. V., Will, N. E., Irmady, K., Lee, F. S., et al. (2013). Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction. Nat. Commun. 4, 2490. doi: 10.1038/ncomms3490
    • (2013) Nat. Commun , vol.4 , pp. 2490
    • Anastasia, A.1    Deinhardt, K.2    Chao, M.V.3    Will, N.E.4    Irmady, K.5    Lee, F.S.6
  • 2
    • 78349311969 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans
    • Antal, A., Chaieb, L., Moliadze, V., Monte-Silva, K., Poreisz, C., Thirugnanasambandam, N., et al. (2010). Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain Stimul. 3, 230-237. doi: 10.1016/j.brs.2009.12.003
    • (2010) Brain Stimul , vol.3 , pp. 230-237
    • Antal, A.1    Chaieb, L.2    Moliadze, V.3    Monte-Silva, K.4    Poreisz, C.5    Thirugnanasambandam, N.6
  • 3
    • 84936068772 scopus 로고    scopus 로고
    • BDNF gene polymorphisms and motor cortical plasticity in healthy humans: when should we consider it?
    • Antal, A., Chaieb, L., Moliadze, V., Zarrouki, D. B., Shoukier, M., and Paulus, W. (2014). BDNF gene polymorphisms and motor cortical plasticity in healthy humans: when should we consider it? J. Neurosci. Rehabil. 1, 1-13.
    • (2014) J. Neurosci. Rehabil. , vol.1 , pp. 1-13
    • Antal, A.1    Chaieb, L.2    Moliadze, V.3    Zarrouki, D.B.4    Shoukier, M.5    Paulus, W.6
  • 4
    • 0035819570 scopus 로고    scopus 로고
    • Resistance training enhances the stability of sensorimotor coordination
    • Carroll, T. J., Barry, B., Riek, S., and Carson, R. G. (2001). Resistance training enhances the stability of sensorimotor coordination. Proc. Biol. Sci. 268, 221-227. doi: 10.1098/rspb.2000.1356
    • (2001) Proc. Biol. Sci , vol.268 , pp. 221-227
    • Carroll, T.J.1    Barry, B.2    Riek, S.3    Carson, R.G.4
  • 5
    • 57049089000 scopus 로고    scopus 로고
    • A common polymorphism in the brain-derived neurotrophic factor gene (BDNF) modulates human cortical plasticity and the response to rTMS
    • Cheeran, B., Talelli, P., Mori, F., Koch, G., Suppa, A., Edwards, M., et al. (2008). A common polymorphism in the brain-derived neurotrophic factor gene (BDNF) modulates human cortical plasticity and the response to rTMS. J. Physiol. 586, 5717-5725. doi: 10.1113/jphysiol.2008.159905
    • (2008) J. Physiol , vol.586 , pp. 5717-5725
    • Cheeran, B.1    Talelli, P.2    Mori, F.3    Koch, G.4    Suppa, A.5    Edwards, M.6
  • 6
    • 33749649795 scopus 로고    scopus 로고
    • Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
    • Chen, Z. Y., Jing, D., Bath, K. G., Ieraci, A., Khan, T., Siao, C. J., et al. (2006). Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 314, 140-143. doi: 10.1126/science.1129663
    • (2006) Science , vol.314 , pp. 140-143
    • Chen, Z.Y.1    Jing, D.2    Bath, K.G.3    Ieraci, A.4    Khan, T.5    Siao, C.J.6
  • 9
    • 50049104884 scopus 로고    scopus 로고
    • The physiological basis of the effects of intermittent theta burst stimulation of the human motor cortex
    • Di Lazzaro, V., Pilato, F., Dileone, M., Profice, P., Oliviero, A., Mazzone, P., et al. (2008). The physiological basis of the effects of intermittent theta burst stimulation of the human motor cortex. J. Physiol. 586, 3871-3879. doi: 10.1113/jphysiol.2008.152736
    • (2008) J. Physiol , vol.586 , pp. 3871-3879
    • Di Lazzaro, V.1    Pilato, F.2    Dileone, M.3    Profice, P.4    Oliviero, A.5    Mazzone, P.6
  • 10
    • 84879967907 scopus 로고    scopus 로고
    • Transcranial direct current stimulation effects on the excitability of corticospinal axons of the human cerebral cortex
    • Di Lazzaro, V., Ranieri, F., Profice, P., Pilato, F., Mazzone, P., Capone, F., et al. (2013). Transcranial direct current stimulation effects on the excitability of corticospinal axons of the human cerebral cortex. Brain Stimul. 6, 641-643. doi: 10.1016/j.brs.2012.09.006
    • (2013) Brain Stimul , vol.6 , pp. 641-643
    • Di Lazzaro, V.1    Ranieri, F.2    Profice, P.3    Pilato, F.4    Mazzone, P.5    Capone, F.6
  • 11
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., et al. (2003). The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112, 257-269.
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3    Goldberg, T.E.4    Kolachana, B.S.5    Bertolino, A.6
  • 12
    • 73449100424 scopus 로고    scopus 로고
    • Effects of aging on the human motor cortical plasticity studied by paired associative stimulation
    • Fathi, D., Ueki, Y., Mima, T., Koganemaru, S., Nagamine, T., Tawfik, A., et al. (2010). Effects of aging on the human motor cortical plasticity studied by paired associative stimulation. Clin. Neurophysiol. 121, 90-93. doi: 10.1016/j.clinph.2009.07.048
    • (2010) Clin. Neurophysiol , vol.121 , pp. 90-93
    • Fathi, D.1    Ueki, Y.2    Mima, T.3    Koganemaru, S.4    Nagamine, T.5    Tawfik, A.6
  • 13
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov, A., Pozzo-Miller, L. D., Olafsson, P., Wang, T., and Lu, B. (1996). Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381, 706-709. doi: 10.1038/381706a0
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo-Miller, L.D.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 14
    • 0001621471 scopus 로고
    • Note on an exact treatment of contingency, goodness of fit and other problems of significance
    • Freeman, G. H., and Halton, J. H. (1951). Note on an exact treatment of contingency, goodness of fit and other problems of significance. Biometrika 38, 141-149.
    • (1951) Biometrika , vol.38 , pp. 141-149
    • Freeman, G.H.1    Halton, J.H.2
  • 17
    • 84903169279 scopus 로고    scopus 로고
    • The Val/Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene predicts decline in perceptual speed in older adults
    • Ghisletta, P., Backman, L., Bertram, L., Brandmaier, A. M., Gerstorf, D., Liu, T., et al. (2014). The Val/Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene predicts decline in perceptual speed in older adults. Psychol. Aging 29, 384-392. doi: 10.1037/a0035201
    • (2014) Psychol. Aging , vol.29 , pp. 384-392
    • Ghisletta, P.1    Backman, L.2    Bertram, L.3    Brandmaier, A.M.4    Gerstorf, D.5    Liu, T.6
  • 18
    • 84878839127 scopus 로고    scopus 로고
    • The role of interneuron networks in driving human motor cortical plasticity
    • Hamada, M., Murase, N., Hasan, A., Balaratnam, M., and Rothwell, J. C. (2013). The role of interneuron networks in driving human motor cortical plasticity. Cereb. Cortex 23, 1593-1605. doi: 10.1093/cercor/bhs147
    • (2013) Cereb. Cortex , vol.23 , pp. 1593-1605
    • Hamada, M.1    Murase, N.2    Hasan, A.3    Balaratnam, M.4    Rothwell, J.C.5
  • 19
    • 84899931552 scopus 로고    scopus 로고
    • Inter- and Intra-individual variability following intermittent theta burst stimulation: implications for rehabilitation and recovery
    • Hinder, M. R., Goss, E. L., Fujiyama, H., Canty, A. J., Garry, M. I., Rodger, J., et al. (2014). Inter- and Intra-individual variability following intermittent theta burst stimulation: implications for rehabilitation and recovery. Brain Stimul. 7, 365-371. doi: 10.1016/j.brs.2014.01.004
    • (2014) Brain Stimul , vol.7 , pp. 365-371
    • Hinder, M.R.1    Goss, E.L.2    Fujiyama, H.3    Canty, A.J.4    Garry, M.I.5    Rodger, J.6
  • 20
    • 77956181530 scopus 로고    scopus 로고
    • Unilateral contractions modulate interhemispheric inhibition most strongly and most adaptively in the homologous muscle of the contralateral limb
    • Hinder, M. R., Schmidt, M. W., Garry, M. I., and Summers, J. J. (2010). Unilateral contractions modulate interhemispheric inhibition most strongly and most adaptively in the homologous muscle of the contralateral limb. Exp. Brain Res. 205, 423-433. doi: 10.1007/s00221-010-2379-z
    • (2010) Exp. Brain Res , vol.205 , pp. 423-433
    • Hinder, M.R.1    Schmidt, M.W.2    Garry, M.I.3    Summers, J.J.4
  • 21
    • 34047108732 scopus 로고    scopus 로고
    • The after-effect of human theta burst stimulation is NMDA receptor dependent
    • Huang, Y. Z., Chen, R. S., Rothwell, J. C., and Wen, H. Y. (2007). The after-effect of human theta burst stimulation is NMDA receptor dependent. Clin. Neurophysiol. 118, 1028-1032. doi: 10.1016/j.clinph.2007.01.021
    • (2007) Clin. Neurophysiol , vol.118 , pp. 1028-1032
    • Huang, Y.Z.1    Chen, R.S.2    Rothwell, J.C.3    Wen, H.Y.4
  • 22
    • 78650178546 scopus 로고    scopus 로고
    • Facilitating skilled right hand motor function in older subjects by anodal polarization over the left primary motor cortex
    • Hummel, F. C., Heise, K., Celnik, P., Floel, A., Gerloff, C., and Cohen, L. G. (2010). Facilitating skilled right hand motor function in older subjects by anodal polarization over the left primary motor cortex. Neurobiol. Aging 31, 2160-2168. doi: 10.1016/j.neurobiolaging.2008.12.008
    • (2010) Neurobiol. Aging , vol.31 , pp. 2160-2168
    • Hummel, F.C.1    Heise, K.2    Celnik, P.3    Floel, A.4    Gerloff, C.5    Cohen, L.G.6
  • 23
    • 84930538793 scopus 로고    scopus 로고
    • Different responses to facilitatory rTMS according to BDNF genotype.
    • [Epub ahead of print].
    • Hwang, J. M., Kim, Y. H., Yoon, K. J., Uhm, K. E., and Chang, W. H. (2014). Different responses to facilitatory rTMS according to BDNF genotype. Clin. Neurophysiol. doi: 10.1016/j.clinph.2014.09.028 [Epub ahead of print].
    • (2014) Clin. Neurophysiol
    • Hwang, J.M.1    Kim, Y.H.2    Yoon, K.J.3    Uhm, K.E.4    Chang, W.H.5
  • 24
    • 84873474317 scopus 로고    scopus 로고
    • Does the longer application of anodal-transcranial direct current stimulation increase corticomotor excitability further? A pilot study
    • Jaberzadeh, S., Bastani, A., and Kidgell, D. (2012). Does the longer application of anodal-transcranial direct current stimulation increase corticomotor excitability further? A pilot study. Basic Clin. Neurosci. 3, 28-35.
    • (2012) Basic Clin. Neurosci. , vol.3 , pp. 28-35
    • Jaberzadeh, S.1    Bastani, A.2    Kidgell, D.3
  • 25
    • 24944574405 scopus 로고    scopus 로고
    • Assessing cardiorespiratory fitness without performing exercise testing
    • Jurca, R., Jackson, A. S., Lamonte, M. J., Morrow, J. R. Jr., Blair, S. N., Wareham, N. J., et al. (2005). Assessing cardiorespiratory fitness without performing exercise testing. Am. J. Prev. Med. 29, 185-193. doi: 10.1016/j.amepre.2005.06.004
    • (2005) Am. J. Prev. Med , vol.29 , pp. 185-193
    • Jurca, R.1    Jackson, A.S.2    Lamonte, M.J.3    Morrow, J.R.4    Blair, S.N.5    Wareham, N.J.6
  • 26
    • 79959326663 scopus 로고    scopus 로고
    • Transcranial direct current stimulation effects on I-wave activity in humans
    • Lang, N., Nitsche, M. A., Dileone, M., Mazzone, P., De Andres-Ares, J., Diaz-Jara, L., et al. (2011). Transcranial direct current stimulation effects on I-wave activity in humans. J. Neurophysiol. 105, 2802-2810. doi: 10.1152/jn.00617.2010
    • (2011) J. Neurophysiol , vol.105 , pp. 2802-2810
    • Lang, N.1    Nitsche, M.A.2    Dileone, M.3    Mazzone, P.4    De Andres-Ares, J.5    Diaz-Jara, L.6
  • 27
    • 84874368904 scopus 로고    scopus 로고
    • Interaction of motor training and intermittent theta burst stimulation in modulating motor cortical plasticity: influence of BDNF Val66Met polymorphism.
    • Lee, M., Kim, S. E., Kim, W. S., Lee, J., Yoo, H. K., Park, K. D., et al. (2013). Interaction of motor training and intermittent theta burst stimulation in modulating motor cortical plasticity: influence of BDNF Val66Met polymorphism. PLoS ONE 8:e57690. doi: 10.1371/journal.pone.0057690
    • (2013) PLoS ONE , vol.8
    • Lee, M.1    Kim, S.E.2    Kim, W.S.3    Lee, J.4    Yoo, H.K.5    Park, K.D.6
  • 28
    • 84899987177 scopus 로고    scopus 로고
    • Inter-individual variability in response to non-invasive brain stimulation paradigms
    • Lopez-Alonso, V., Cheeran, B., Rio-Rodriguez, D., and Fernandez-Del-Olmo, M. (2014). Inter-individual variability in response to non-invasive brain stimulation paradigms. Brain Stimul. 7, 372-380. doi: 10.1016/j.brs.2014.02.004
    • (2014) Brain Stimul , vol.7 , pp. 372-380
    • Lopez-Alonso, V.1    Cheeran, B.2    Rio-Rodriguez, D.3    Fernandez-Del-Olmo, M.4
  • 29
    • 84948712203 scopus 로고    scopus 로고
    • Intra-individual variability in the response to anodal transcranial direct current stimulation.
    • [Epub ahead of print].
    • Lopez-Alonso, V., Fernandez-Del-Olmo, M., Costantini, A., Gonzalez-Henriquez, J. J., and Cheeran, B. (2015). Intra-individual variability in the response to anodal transcranial direct current stimulation. Clin. Neurophysiol. doi: 10.1016/j.clinph.2015.03.022 [Epub ahead of print].
    • (2015) Clin. Neurophysiol
    • Lopez-Alonso, V.1    Fernandez-Del-Olmo, M.2    Costantini, A.3    Gonzalez-Henriquez, J.J.4    Cheeran, B.5
  • 30
    • 84872422287 scopus 로고    scopus 로고
    • The BDNF val(66)met polymorphism is not related to motor function or short-term cortical plasticity in elderly subjects
    • McHughen, S. A., and Cramer, S. C. (2013). The BDNF val(66)met polymorphism is not related to motor function or short-term cortical plasticity in elderly subjects. Brain Res. 1495, 1-10. doi: 10.1016/j.brainres.2012.12.004
    • (2013) Brain Res , vol.1495 , pp. 1-10
    • McHughen, S.A.1    Cramer, S.C.2
  • 31
    • 42549172719 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly
    • Miyajima, F., Ollier, W., Mayes, A., Jackson, A., Thacker, N., Rabbitt, P., et al. (2008). Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly. Genes Brain Behav. 7, 411-417. doi: 10.1111/j.1601-183X.2007.00363.x
    • (2008) Genes Brain Behav , vol.7 , pp. 411-417
    • Miyajima, F.1    Ollier, W.2    Mayes, A.3    Jackson, A.4    Thacker, N.5    Rabbitt, P.6
  • 32
    • 43449108843 scopus 로고    scopus 로고
    • Interindividual variability and age-dependency of motor cortical plasticity induced by paired associative stimulation
    • Muller-Dahlhaus, J. F. M., Orekhov, Y., Liu, Y., and Ziemann, U. (2008). Interindividual variability and age-dependency of motor cortical plasticity induced by paired associative stimulation. Exp. Brain Res. 187, 467-475. doi: 10.1007/s00221-008-1319-7
    • (2008) Exp. Brain Res , vol.187 , pp. 467-475
    • Muller-Dahlhaus, J.F.M.1    Orekhov, Y.2    Liu, Y.3    Ziemann, U.4
  • 33
    • 0035960657 scopus 로고    scopus 로고
    • Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans
    • Nitsche, M. A., and Paulus, W. (2001). Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology 57, 1899-1901.
    • (2001) Neurology , vol.57 , pp. 1899-1901
    • Nitsche, M.A.1    Paulus, W.2
  • 34
    • 77954521828 scopus 로고    scopus 로고
    • Determinants of the induction of cortical plasticity by non-invasive brain stimulation in healthy subjects
    • Ridding, M. C., and Ziemann, U. (2010). Determinants of the induction of cortical plasticity by non-invasive brain stimulation in healthy subjects. J. Physiol. 588, 2291-2304. doi: 10.1113/jphysiol.2010.190314
    • (2010) J. Physiol , vol.588 , pp. 2291-2304
    • Ridding, M.C.1    Ziemann, U.2
  • 35
    • 73449116409 scopus 로고    scopus 로고
    • Corticomotor plasticity and learning of a ballistic thumb training task are diminished in older adults
    • Rogasch, N. C., Dartnall, T. J., Cirillo, J., Nordstrom, M. A., and Semmler, J. G. (2009). Corticomotor plasticity and learning of a ballistic thumb training task are diminished in older adults. J. Appl. Physiol. 107, 1874-1883. doi: 10.1152/japplphysiol.00443.2009
    • (2009) J. Appl. Physiol , vol.107 , pp. 1874-1883
    • Rogasch, N.C.1    Dartnall, T.J.2    Cirillo, J.3    Nordstrom, M.A.4    Semmler, J.G.5
  • 36
    • 51149101443 scopus 로고    scopus 로고
    • Cortisol inhibits neuroplasticity induction in human motor cortex
    • Sale, M. V., Ridding, M. C., and Nordstrom, M. A. (2008). Cortisol inhibits neuroplasticity induction in human motor cortex. J. Neurosci. 28, 8285-8293. doi: 10.1523/JNEUROSCI.1963-08.2008
    • (2008) J. Neurosci , vol.28 , pp. 8285-8293
    • Sale, M.V.1    Ridding, M.C.2    Nordstrom, M.A.3
  • 37
    • 77953735312 scopus 로고    scopus 로고
    • Genotyping the BDNF rs6265 (val66met) polymorphism by one-step amplified refractory mutation system PCR
    • Sheikh, H. I., Hayden, E. P., Kryski, K. R., Smith, H. J., and Singh, S. M. (2010). Genotyping the BDNF rs6265 (val66met) polymorphism by one-step amplified refractory mutation system PCR. Psychiatr Genet. 20, 109-112. doi: 10.1097/YPG.
    • (2010) Psychiatr Genet. , vol.20 , pp. 109-112
    • Sheikh, H.I.1    Hayden, E.P.2    Kryski, K.R.3    Smith, H.J.4    Singh, S.M.5
  • 38
    • 79952159949 scopus 로고    scopus 로고
    • Physiological basis of transcranial direct current stimulation
    • Stagg, C. J., and Nitsche, M. A. (2011). Physiological basis of transcranial direct current stimulation. Neuroscientist 17, 37-53. doi: 10.1177/1073858410386614
    • (2011) Neuroscientist , vol.17 , pp. 37-53
    • Stagg, C.J.1    Nitsche, M.A.2
  • 39
    • 84929961220 scopus 로고    scopus 로고
    • BDNF-Val66Met-polymorphism impact on cortical plasticity in schizophrenia patients: a proof of concept study
    • Strube, W., Nitsche, M. A., Wobrock, T., Bunse, T., Rein, B., Herrmann, M., et al. (2015). BDNF-Val66Met-polymorphism impact on cortical plasticity in schizophrenia patients: a proof of concept study. Int. J. Neuropsychopharmacol. 18, 1-11. doi: 10.1093/ijnp/pyu040
    • (2015) Int. J. Neuropsychopharmacol , vol.18 , pp. 1-11
    • Strube, W.1    Nitsche, M.A.2    Wobrock, T.3    Bunse, T.4    Rein, B.5    Herrmann, M.6
  • 40
    • 84898056768 scopus 로고    scopus 로고
    • Late cortical plasticity in motor and auditory cortex: role of met-allele in BDNF Val66Met polymorphism
    • Teo, J. T., Bentley, G., Lawrence, P., Soltesz, F., Miller, S., Wille, D., et al. (2014). Late cortical plasticity in motor and auditory cortex: role of met-allele in BDNF Val66Met polymorphism. Int. J. Neuropsychopharmacol. 17, 705-713. doi: 10.1017/S1461145713001636
    • (2014) Int. J. Neuropsychopharmacol , vol.17 , pp. 705-713
    • Teo, J.T.1    Bentley, G.2    Lawrence, P.3    Soltesz, F.4    Miller, S.5    Wille, D.6
  • 41
    • 84936115254 scopus 로고    scopus 로고
    • Neurochemical modulation in posteromedial default-mode network cortex induced by transcranial magnetic stimulation.
    • [Epub ahead of print].
    • Vidal-Pineiro, D., Martin-Trias, P., Falcon, C., Bargallo, N., Clemente, I. C., Valls-Sole, J., et al. (2015). Neurochemical modulation in posteromedial default-mode network cortex induced by transcranial magnetic stimulation. Brain Stimul. doi: 10.1016/j.brs.2015.04.005 [Epub ahead of print].
    • (2015) Brain Stimul
    • Vidal-Pineiro, D.1    Martin-Trias, P.2    Falcon, C.3    Bargallo, N.4    Clemente, I.C.5    Valls-Sole, J.6
  • 42
    • 84899905955 scopus 로고    scopus 로고
    • Variability in response to transcranial direct current stimulation of the motor cortex
    • Wiethoff, S., Hamada, M., and Rothwell, J. C. (2014). Variability in response to transcranial direct current stimulation of the motor cortex. Brain Stimul. 7, 468-475. doi: 10.1016/j.brs.2014.02.003
    • (2014) Brain Stimul , vol.7 , pp. 468-475
    • Wiethoff, S.1    Hamada, M.2    Rothwell, J.C.3
  • 43
    • 84859060637 scopus 로고    scopus 로고
    • Interaction of BDNF and COMT polymorphisms on paired-associative stimulation-induced cortical plasticity
    • Witte, A. V., Kurten, J., Jansen, S., Schirmacher, A., Brand, E., Sommer, J., et al. (2012). Interaction of BDNF and COMT polymorphisms on paired-associative stimulation-induced cortical plasticity. J. Neurosci. 32, 4553-4561. doi: 10.1523/JNEUROSCI.6010-11.2012
    • (2012) J. Neurosci , vol.32 , pp. 4553-4561
    • Witte, A.V.1    Kurten, J.2    Jansen, S.3    Schirmacher, A.4    Brand, E.5    Sommer, J.6
  • 44
    • 23044464168 scopus 로고    scopus 로고
    • Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
    • Woo, N. H., Teng, H. K., Siao, C. J., Chiaruttini, C., Pang, P. T., Milner, T. A., et al. (2005). Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Nat. Neurosci. 8, 1069-1077. doi: 10.1038/nn1510
    • (2005) Nat. Neurosci , vol.8 , pp. 1069-1077
    • Woo, N.H.1    Teng, H.K.2    Siao, C.J.3    Chiaruttini, C.4    Pang, P.T.5    Milner, T.A.6
  • 45
    • 0033825170 scopus 로고    scopus 로고
    • I-waves in motor cortex
    • Ziemann, U., and Rothwell, J. C. (2000). I-waves in motor cortex. J. Clin. Neurophysiol. 17, 397-405. doi: 10.1097/00004691-200007000-00005
    • (2000) J. Clin. Neurophysiol , vol.17 , pp. 397-405
    • Ziemann, U.1    Rothwell, J.C.2
  • 46
    • 80755163707 scopus 로고    scopus 로고
    • Non-invasive brain stimulation: enhancing motor and cognitive functions in healthy old subjects
    • Zimerman, M., and Hummel, F. C. (2010). Non-invasive brain stimulation: enhancing motor and cognitive functions in healthy old subjects. Front. Aging Neurosci. 2:149. doi: 10.3389/fnagi.2010.00149
    • (2010) Front. Aging Neurosci. , vol.2 , pp. 149
    • Zimerman, M.1    Hummel, F.C.2
  • 47
    • 84873401660 scopus 로고    scopus 로고
    • Neuroenhancement of the aging brain: restoring skill acquisition in old subjects
    • Zimerman, M., Nitsch, M., Giraux, P., Gerloff, C., Cohen, L. G., and Hummel, F. C. (2013). Neuroenhancement of the aging brain: restoring skill acquisition in old subjects. Ann. Neurol. 73, 10-15. doi: 10.1002/ana.23761
    • (2013) Ann. Neurol , vol.73 , pp. 10-15
    • Zimerman, M.1    Nitsch, M.2    Giraux, P.3    Gerloff, C.4    Cohen, L.G.5    Hummel, F.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.