Life cycle inventory improvement in the pharmaceutical sector: Assessment of the sustainability combining PMI and LCA tools

Green Chemistry

Volumn 17, Issue 6, 2015, Pages 3390-3400

  Cespi, Daniele ^a,b   Beach, Evan S ^a   Swarr, Thomas E ^c   Passarini, Fabrizio ^b,d   Vassura, I ^b,d   Dunn, Peter J ^e   Anastas, Paul T ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Yale School of the Environment   (United States)

^d Centro Interdipardimentale di Ricerca Industriale Energia e Ambiente   (Italy)

^e PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84935887796     PISSN: 14639262     EISSN: 14639270     Source Type: Journal    
DOI: 10.1039/c5gc00424a     Document Type: Article

References (60)

1. G. Wernet S. Conradt H. P. Isenring C. Jiménez-González K. Hungerbühler Int. J. Life Cycle Assess. 2010 15 294 303
2. C. Jiménez-González A. D. Curzons D. J. C. Constable V. L. Cunningham Int. J. Life Cycle Assess. 2004 9 114 121
3. ACS GCIPR - American Chemical Society, Green Chemistry Institute, Pharmaceutical Roundtable website http://www.acs.org/gcipharmaroundtable
4. C. Jiménez-González P. Poechlauer Q. B. Broxterman B. S. Yang D. am Ende J. Baird C. Bertsch R. E. Hannah P. Dell'Orco H. Noorman S. Yee R. Reintjens A. Wells V. Massonneau J. Maley Org. Process Res. Dev. 2011 15 900 911
5. C. Jiménez-González C. Ollech W. Pyrz D. Hughes Q. B. Broxterman N. Bhathela Org. Process Res. Dev. 2013 17 239 246
6. L. M. Tufvesson P. Tufvesson J. Woodley P. Börjesson Int. J. Life Cycle Assess. 2013 18 431 444
7. H. Baumann and A.-M. Tillman, The Hitch Hiker's Guide to LCA: An Orientation in Life Cycle Assessment Methodology and Application, Studentlitteratur AB, Lund, Sweden, 2004
8. G. Wernet S. Hellweg K. Hungerbühler Int. J. Life Cycle Assess. 2012 17 720 728
9. C. Jiménez-González C. S. Ponder Q. B. Broxterman J. B. Maley Org. Process Res. Dev. 2011 15 912 917
10. C. Jiménez-González M. R. Overcash Green Chem. 2014 16 3392 3400
11. G. Geisler T. B. Hofstetter K. Hungerbühler Int. J. Life Cycle Assess. 2004 9 101 113
12. G. Wernet S. Papadokonstantakis S. Hellweg K. Hungerbühler Green Chem. 2009 11 1826 1831
13. D. J. Dale P. J. Dunn C. Golightly M. L. Hughes P. C. Levett A. K. Pearce P. M. Searle G. Ward A. S. Wood Org. Process Res. Dev. 2000 4 17 22
14. P. J. Dunn S. Galvin K. Hettenbach Green Chem. 2004 6 43 48
15. F. Roschangar R. A. Sheldon C. H. Senanayake Green Chem. 2015 17 752 768
16. P. J. Dunn, A. S. Wells and M. T. Williams, Green Chemistry in the Pharmaceutical Industry, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2010
17. P. T. Anastas and J. C. Warner, Green Chemistry: Theory and Practice, Oxford University Press, Oxford, 1998
18. R. A. Sheldon Chem. Ind. 1992 903 906
19. R. A. Sheldon Chem. Ind. 1997 12 15
20. B. M. Trost Science 1991 254 1471 1477
21. P. T. Anastas J. B. Zimmerman Environ. Sci. Technol. 2003 37 94 101
22. C. Jiménez-González D. J. C. Constable C. S. Ponder Chem. Soc. Rev. 2012 41 1485 1498
23. DIN EN ISO 14040, Environmental Management, Life Cycle Assessment, Principles and Framework, DIN (Deutsches Institut für Normung e.V.), Beuth Verlag, Berlin, Germany, 2006
24. DIN EN ISO 14044, Environmental Management, Life Cycle Assessment, Requirements and Guidelines, DIN (Deutsches Institut für Normung e. V.), Beuth Verlag, Berlin, Germany, 2006
25. P. T. Anastas R. L. Lankey Green Chem. 2000 2 289 295
26. D. Cespi F. Passarini E. Neri I. Vassura L. Ciacci F. Cavani J. Clean. Prod. 2014 69 17 25
27. D. Cespi F. Passarini G. Mastragostino I. Vassura S. Larocca A. Iaconi A. Chieregato J.-L. Dubois F. Cavani Green Chem. 2015 17 343 355
28. N. von der Assen A. Bardow Green Chem. 2014 16 3272 3280
29. H. A. van Kalkeren A. L. Blom F. P. J. T. Rutjies M. A. J. Huijbregts Green Chem. 2013 15 1255 1263
30. D. Ott D. Kralisch I. Denčić V. Hessel Y. Laribi P. D. Perrichon C. Berguerand L. Kiwi-Minsker P. Loeb ChemSusChem 2014 12 3521 3533
31. C. Jiménez-González A. D. Curzons D. J. C. Constable V. L. Cunningham J. Clean Technol. Environ. Policy 2004 7 42 50
32. G. Jödicke O. Zenklusen A. Weidenhaupt K. Hungerbühler J. Clean. Prod. 1999 7 159 166
33. S. Kim C. Jiménez-González B. E. Dale Int. J. Life Cycle Assess. 2009 14 392 400
34. A. S. Bell, D. Brown and N. K. Terrett, EU Pat, 0 463 756 A1, 1991
35. Ecoinvent Centre (formerly Swiss Centre for Life Cycle Inventories) (2009) Ecoinvent 2.2 Database
36. R. Hischier S. Hellweg C. Capello A. Primas Int. J. Life Cycle Assess. 2005 10 59 67
37. H.-D. Hahn, G. Dämbkes, N. Rupprich and H. Bahl, Butanols, Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2010, 10.1002/14356007.a04-463.pub2
38. S. Sridhar and R. G. Carter, Diamines and Higher Amines, Aliphatic, Kirk-Othmer Encyclopedia of Chemical Technology, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2001, 10.1002/0471238961.0409011303011820.a01.pub2
39. S. H. Vanderpool and P. S. Morford, US Pat., 4 727 143, 1988
40. S. Shimizu, N. Watanabe, T. Kataoka, T. Shoji, N. Abe, S. Morishita and H. Ichimura, Pyridine and Pyridine Derivatives, in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2000, 10.1002/14356007.a22-399
41. SciFinder® https://scifinder.cas.org
42. M. R. Thomas, Salicylic Acid and Related Compounds, Kirk-Othmer Encyclopedia of Chemical Technology, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2000, 10.1002/0471238961.1901120920081513.a01
43. W. B. McCormack and B. C. Lawes, Sulfuric and Sulfurous Esters, Kirk-Othmer Encyclopedia of Chemical Technology, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2000, 10.1002/0471238961.1921120613030315.a01
44. A. Szïjjarto S. Papadokonstantakis U. Fischer K. Hungerbühler Ind. Eng. Chem. Res. 2008 47 7323 7334
45. G. Van der Vorst J. Dewulf W. Aelterman B. De Witte H. Van Langenhove Ind. Eng. Chem. Res. 2009 48 5344 5350
46. Gendorf, Umwelterklärung 2000, Industrial Park Werk Gendorf, Burgkirchen, 2000
47. HIS - Process Economics Program (PEP), http://chemical.ihs.com/PEP/yearbook.htm (accessed February 2015)
48. Nexant - Process Economics and Research Planning (PERP), http://thinking.nexant.com/program/process-evaluationresearch-planning, (accessed February 2015)
49. G. Wernet S. Hellweg U. Fischer S. Papadokonstantakis K. Hungerbühler Environ. Sci. Technol. 2008 42 6717 6722
50. VDI - Verein Deutscher Ingenieure, VDI-richtlinie 4600: Cumulative energy demand, terms, defiitions, methods of calculation, Düsseldorf, Germany, 1997
51. G. Wernet C. Mutel S. Hellweg K. Hungerbühler J. Ind. Ecol. 2011 15 96 107
52. H. J. Althaus, M. Chudacoff, R. Hischier, N. Jungbluth, M. Osses and A. Primas, Life Cycle Inventories of Chemicals. Ecoinvent report No. 8, v2.0, EMPA Dübendorf, Swiss Centre for Life Cycle Inventories, Dübendorf, CH, 2007
53. R. A. Sheldon Green Chem. 2007 9 1273 1283
54. D. J. C. Constable A. D. Curzons V. L. Cunningham Green Chem. 2002 4 521 527
55. P. R. Consultants, SimaPro7, PhD version 7.3.3, Amersfoort, The Netherlands, 2013
56. M. Goedkoop, R. Heijungs, M. Huijbregts, A. De Schryver, J. Struijs and R. van Zelm, ReCiPe 2008 - A life cycle impact assessment method which comprises harmonised category indicators at the midpoint and the endpoint level, First edition (version 1.08), Ministry of Housing, Spatial Planning and the Environment (VROM), Netherlands, 2013
57. IPCC - Intergovernmental Panel on Climate Change, Climate Change 2013. The Physical Science Basis. Fifth Assessment Report, Cambridge University Press, United Kingdom, 2013
58. R. Frischknecht, N. Jungbluth, H.-J. Althaus, C. Bauer, G. Doka, R. Dones, R. Hischier, S. Hellweg, S. Humbert, T. Köllner, Y. Loerincik, M. Margni and T. Nemecek, Implementation of Life Cycle Impact Assessment Methods. ecoinvent report No. 3, v2.0, Swiss Centre for Life Cycle Inventories, Dübendorf, 2007
59. H. Sugiyama U. Fischer K. Hungerbuhler M. Hirao AIChE J. 2008 54 1037 1053
60. A. D. Patel K. Meesters H. den Uil E. de Jong K. Blok M. K. Patel Energy Environ. Sci. 2012 5 8430 8444