Associations of lead and cadmium with sex hormones in adult males

Environmental Research

Volumn 142, Issue , 2015, Pages 25-33

  Kresovich, Jacob K ^a   Argos, Maria ^a   Turyk, Mary E ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Cadmium; Lead; NHANES; Sex hormones; Testosterone

Indexed keywords

ANDROSTANEDIONE GLUCURONIDE; CADMIUM; ESTRADIOL; GLUCURONIDE; LEAD; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; UNCLASSIFIED DRUG; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; POLLUTANT; SEX HORMONE;

ADULT; BIOMARKER; BLOOD; CADMIUM; LEAD; MALE; METABOLISM; POLLUTION EXPOSURE; SEX HORMONE; SMOKING; STEROID;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; DIABETES MELLITUS; HEALTH CARE SURVEY; HUMAN; INVESTIGATIVE PROCEDURES; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; SMOKING; STEROIDOGENESIS; UNITED STATES; ADVERSE EFFECTS; ANALYSIS; BLOOD; ENVIRONMENTAL EXPOSURE; NUTRITION; POLLUTANT; STATISTICAL ANALYSIS; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; BODY MASS INDEX; CADMIUM; DATA INTERPRETATION, STATISTICAL; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; GONADAL STEROID HORMONES; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LEAD; MALE; MIDDLE AGED; NUTRITION SURVEYS; SEX HORMONE-BINDING GLOBULIN; YOUNG ADULT;

EID: 84935852024     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2015.05.026     Document Type: Article

References (40)

1. Adams S.V., Newcomb P.A. Cadmium blood and urine concentrations as measures of exposure: NHANES 1999-2010. J. Expo. Sci. Environ. Epidemiol. 2014, 24:163-170.
2. Attia A.M., et al. Cigarette smoking and male reproduction. Arch. Androl. 1989, 23:45-49.
3. Bond A., Davis C. Sex hormone binding globulin in clinical perspective. Acta Obstet. Gynecol. Scand. 1987, 66:255-262.
4. Colborn T., et al. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 1993, 101:378-384.
5. Corona G., et al. Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study. Eur. J. Endocrinol. 2011, 165:687-701.
6. Dai W.S., et al. Cigarette smoking and serum sex hormones in men. Am. J. Epidemiol. 1988, 128:796-805.
7. Dhooge W., et al. Internal exposure to pollutants and sex hormone levels in Flemish male adolescents in a cross-sectional study: associations and dose-response relationships. J. Expo. Sci. Environ. Epidemiol. 2011, 21:106-113.
8. Field A.E., et al. The relation of smoking, age, relative weight, and dietary intake to serum adrenal steroids, sex hormones, and sex hormone-binding globulin in middle-aged men. J. Clin. Endocrinol. Metab. 1994, 79:1310-1316.
9. Goncharov A., et al. Lower serum testosterone associated with elevated polychlorinated biphenyl concentrations in Native American men. Environ. Health Perspect. 2009, 117:1454-1460.
10. Hall J.E. Guyton and Hall Textbook of Medical Physiology 2010, Elsevier, Philadelphia, Pa., London, Saunders.
11. Hedderson M.M., et al. Prepregnancy SHBG concentrations and risk for subsequently developing gestational diabetes mellitus. Diabetes Care 2014, 37:1296-1303.
12. Jurasović J., et al. Semen quality and reproductive endocrine function with regard to blood cadmium in Croatian male subjects. Biometals 2004, 17:735-743.
13. Krassas G.E., et al. Thyroid function and human reproductive health. Endocr. Rev. 2010, 31:702-755.
14. Laaksonen D.E., et al. Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diabetes Care 2004, 27:1036-1041.
15. Lewis R.C., Meeker J.D. Biomarkers of exposure to molybdenum and other metals in relation to testosterone among men from the United States National Health and Nutrition Examination Survey 2011-2012. Fertil. Steril. 2015, 103:172-178.
16. Mayo Clinic, Lead poisoning causes. In: M. F. f. M. E. a. Research, (Ed.), vol. 2014, 2014.
17. Meeker J.D., Ferguson K.K. Urinary phthalate metabolites are associated with decreased serum testosterone in men, women, and children from NHANES 2011-2012. J. Clin. Endocrinol. Metab. 2014, 99:4346-4352.
18. Menke A., et al. The association of urinary cadmium with sex steroid hormone concentrations in a general population sample of US adult men. BMC Public Health 2008, 8:72.
19. Münzker J. Testosterone to dihydrotestosterone ratio as a new biomarker for an adverse metabolic phenotype in the polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 2015, 100(2):653-660.
20. National Health and Nutrition Examination Survey, 2002. Nutritional Biochemistries (LAB06). 1999-2000 Data Documentation, Codebook, and Frequencies.
21. National Health and Nutrition Examination Survey, 2006. Nutritional Biochemistries (LAB06). 2002-2004 Data Documentation, Codebook, and Frequencies.
22. Nebert D.W., Russell D.W. Clinical importance of the cytochromes P450. Lancet 2002, 360:1155-1162.
23. Pizent A., et al. Reproductive toxicity of metals in men. Arh Hig Rada Toksikol. 2012, 63(Suppl. 1):S35-S46.
24. Rodamilans M., et al. Lead toxicity on endocrine testicular function in an occupationally exposed population. Hum. Toxicol. 1988, 7:125-128.
25. Shiels M.S., et al. Association of cigarette smoking, alcohol consumption, and physical activity with sex steroid hormone levels in US men. Cancer Causes Control 2009, 20:877-886.
26. Sieri S., et al. Prospective study on the role of glucose metabolism in breast cancer occurrence. Int. J. Cancer 2012, 130:921-929.
27. Singleton D.W., Khan S.A. Xenoestrogen exposure and mechanisms of endocrine disruption. Front. Biosci. 2003, 8:s110-s118.
28. Somervaille L.J., et al. In vivo tibia lead measurements as an index of cumulative exposure in occupationally exposed subjects. Br. J. Ind. Med. 1988, 45:174-181.
29. Sommar J.N., et al. Investigation of lead concentrations in whole blood, plasma and urine as biomarkers for biological monitoring of lead exposure. J. Expo. Sci. Environ. Epidemiol. 2014, 24:51-57.
30. Specht I.O., et al. Associations between serum phthalates and biomarkers of reproductive function in 589 adult men. Environ. Int. 2014, 66:146-156.
31. Svartberg J., et al. Association of endogenous testosterone with blood pressure and left ventricular mass in men. Tromsø Study Eur. J. Endocrinol. 2004, 150:65-71.
32. Takiguchi M., Yoshihara S. New aspects of cadmium as endocrine disruptor. Environ. Sci. 2006, 13:107-116.
33. Telisman S., et al. Reproductive toxicity of low-level lead exposure in men. Environ. Res. 2007, 105:256-266.
34. Telisman S., et al. Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men. Environ. Health Perspect. 2000, 108:45-53.
35. Thomas P. Teleost model for studying the effects of chemicals on female reproductive endocrine function. J. Exp. Zool. Suppl. 1990, 4:126-128.
36. United States Agency for Toxic Substances and Disease Registry, 2007. Toxicological Profile for Lead. Agency for Toxic Substances and Disease Registry. Atlanta, Ga.
37. United States Agency for Toxic Substances and Disease Registry, 2008. Draft Toxicological Profile for Cadmium. U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry. Atlanta, Ga, p. 1 online resource (xx, 454, 37 p.).
38. Vermeulen A., et al. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin. Endocrinol. Metab. 1999, 84:3666-3672.
39. Vlachopoulos C., et al. Testosterone deficiency: a determinant of aortic stiffness in men. Atherosclerosis 2014, 233:278-283.
40. Wang W., et al. Cigarette smoking has a positive and independent effect on testosterone levels. Hormones (Athens) 2013, 12:567-577.