Syntheses of Dap-3 Polymyxin Analogues via a Tris-Boc-Protected Polymyxin B Heptapeptide

Synthesis (Germany)

Volumn 47, Issue 14, 2015, Pages 2088-2092

  Li, Bryan ^a   Akin, Anne ^a   Magee, Thomas V ^a   Martinez, Carlos ^a   Szeliga, Jan ^a   Vuong, Duc Vicki ^a  

^a PFIZER INC   (United States)

Author keywords

antibacterial; enzymatic hydrolysis; heptapeptide; polymyxin; Savinase

Indexed keywords

HYDROLYSIS;

ANTIBACTERIAL; CHROMATOGRAPHIC ISOLATION; HEPTAPEPTIDES; POLYMYXIN; REACTION MIXTURE; REGIO-SELECTIVE; SAVINASE; SEMISYNTHESIS;

ENZYMATIC HYDROLYSIS;

ANTIINFECTIVE AGENT; COLISTIN; HEPTAPEPTIDE; HEPTAPEPTIDE BOC3; HEPTAPEPTIDE BOC5; POLYMYXIN; POLYMYXIN DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; COST EFFECTIVENESS ANALYSIS; DRUG HYDROLYSIS; DRUG ISOLATION; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

EID: 84935500648     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0034-1380549     Document Type: Article

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