Euterpe oleracea Mart. extract prevents vascular remodeling and endothelial dysfunction in spontaneously hypertensive rats

International Journal of Applied Research in Natural Products

Volumn 8, Issue 3, 2015, Pages 6-16

  Cordeiro, Viviane S C ^a   Carvalho, Lenize C R M ^a   De Bem, Graziele F ^a   Costa, Cristiane A ^a   Souza, ^a   Sousa, Pergentino José C ^b   Souza, Marcelo Augusto V ^a   Rocha, Vinícius N ^c   Carvalho, Jorge José ^a   De Moura, Roberto S ^a   Resende, Angela C ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF PARÁ   (Brazil)

^c FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

Endothelial dysfunction; Euterpe oleracea mart; Hypertension; Oxidative stress; Vascular hypertrophy

Indexed keywords

ACETYLCHOLINE; ANTIHYPERTENSIVE AGENT; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EUTERPE OLERACEA EXTRACT; GLUTATHIONE PEROXIDASE; NITRITE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD VESSEL PARAMETERS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; ELASTIC FIBER; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; EUTERPE OLERACEA; HISTOPATHOLOGY; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MEDIA LUMEN RATIO; NONHUMAN; OXIDATIVE STRESS; PLANT SEED; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; UPREGULATION; VASCULAR REMODELING;

EUTERPE; EUTERPE OLERACEA; RATTUS;

EID: 84935457551     PISSN: None     EISSN: 19406223     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. James PA, Oparil S, Carter BL et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;(311):507-520. doi:10.1001/jama.2013.284427.
2. Hajjar I, Kotchen JM, Kotchen TA. Hypertension: trends in prevalence, incidence, and control. Annu Rev Public Health. 2006;(27):465-490. doi: 10.1146/annurev.publhealth.27.021405.102132.
3. Touyz RM. Advancement in hypertension pathogenesis: some new concepts. Curr Opin Nephrol Hypertens. 2011;(20):105-106. doi:10.1097/MNH.0b013e328343f526.
4. West JD, Marnett LJ. Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal. Chem Res Toxicol. 2005;(18):1642-1653. doi: 10.1021/tx050211n.
5. Lam CF, Peterson TE, Richardson DM et al. Increased blood flow causes coordinated upregulation of arterial eNOS and biosynthesis of tetrahydrobiopterin. Am J Physiol Heart Circ Physiol. 2006;(290):H786-H793. doi: 10.1152/ajpheart.00759.2005.
6. Traub O, Berk BC. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol. 1998;(18):677-685. doi: 10.1161/01.ATV.18.5.677.
7. Montezano AC, Touyz RM. Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases. Basic Clin Pharmacol Toxicol. 2012;(110):87-94. doi: 10.1111/j.1742-7843.2011.00785.x.
8. Lawes CM, Vander HS, Rodgers A. Global burden of blood-pressure-related disease, 2001. Lancet. 2008;(371):1513-1518. doi:10.1016/S0140-6736(08)60655-8.
9. Curin Y, Andriantsitohaina R. Polyphenols as potential therapeutical agents against cardiovascular diseases. Pharmacol Rep. 2005;(57 Suppl):97-107. http://www.if-pan.krakow.pl/pjp/pdf/2005/s_97.pdf.
10. Sangronis E, Sanabria N. Impact of solar dehydration on composition and antioxidant properties of acai (Euterpe oleracea Mart.). Arch Latinoam Nutr. 2011;(61):74-80. PMID: 22097293.
11. Rodrigues RB, Lichtenthaler R, Zimmermann BF et al. Total oxidant scavenging capacity of Euterpe oleracea Mart. (acai) seeds and identification of their polyphenolic compounds. J Agric Food Chem. 2006;(54):4162-4167. doi: 10.1021/jf058169p.
12. Rocha AP, Carvalho LC, Sousa MA et al. Endothelium-dependent vasodilator effect of Euterpe oleracea Mart. (Acai) extracts in mesenteric vascular bed of the rat. Vascul Pharmacol. 2007;(46):97-104. doi: 10.1016/j.vph.2006.08.411.
13. da Costa CA, de Oliveira PR, de Bem GF et al. Euterpe oleracea Mart.-derived polyphenols prevent endothelial dysfunction and vascular structural changes in renovascular hypertensive rats: role of oxidative stress. Naunyn Schmiedebergs Arch Pharmacol. 2012;(385):1199-1209. doi: 10.1007/s00210-012-0798-z.
14. Rocha AP, Resende AC, Sousa MAV et al. Antihypertensive effects and antioxidant action of a hydro-alcoholic extract obtained from fruits of Euterpe oleracea Mart. (Açaí). Journal of Pharmacology and Toxicology. 2008;3 (6):435-448. doi: 10.3923/jpt.2008.435.448.
15. Sekiguchi F, Adachi T, Matsubara H et al. Spontaneous and agonist-induced contractions and endothelium-dependent relaxation in aortae from SHRSP and WKY rats under various levels of passive force. Clin Exp Pharmacol Physiol. 1996;(23):483-489. PMID:8800570.
16. Ulker S, McKeown PP, Bayraktutan U. Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities. Hypertension. 2003;(41):534-539. doi: 10.1161/01.HYP.0000057421.28533.37.
17. Moura RS, Ferreira TS, Lopes AA et al. Effects of Euterpe oleracea Mart. (ACAI) extract in acute lung inflammation induced by cigarette smoke in the mouse. Phytomedicine. 2012;(19):262-269. doi: 10.1016/j.phymed.2011.11.004.
18. McGregor DD. The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat. J Physiol. 1965;(177):21-30. PMID: 14296957.
19. Draper HH, Squires EJ, Mahmoodi H et al. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Radic Biol Med. 1993;(15):353-363. PMID: 8225017.
20. Costa CA, Amaral TA, Carvalho LC et al. Antioxidant treatment with tempol and apocynin prevents endothelial dysfunction and development of renovascular hypertension. Am J Hypertens. 2009;(22):1242-1249. doi: 10.1038/ajh.2009.186.
21. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of proteindye binding. Anal Biochem. 1976;(72):248-254. PMID: 942051.
22. Green LC, Wagner DA, Glogowski J et al. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem. 1982;(126):131-138. doi:10.1016/0003-2697(82)90118-x.
23. Felix A, Monteiro N, Rocha VN et al. Remodeling of the thoracic aorta after bone marrow cell transplantation. Int J Clin Exp Pathol. 2014;(7):5527-5537. PMCID: PMC4203165.
24. Moraes-Teixeira JA, Felix A, Fernandes-Santos C et al. Exercise training enhances elastin, fibrillin and nitric oxide in the aorta wall of spontaneously hypertensive rats. Exp Mol Pathol. 2010;(89):351-357. doi: 10.1016/j.yexmp.2010.08.004.
25. Chen X, Touyz RM, Park JB, Schiffrin EL. Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR. Hypertension. 2001;(38):606-611. doi: 10.1161/hy09t1.094005.
26. Vaziri ND, Ni Z, Oveisi F, Trnavsky-Hobbs DL. Effect of antioxidant therapy on blood pressure and NO synthase expression in hypertensive rats. Hypertension. 2000;(36):957-964. doi: 10.1161/01.HYP.36.6.957.
27. Cabassi A, Dumont EC, Girouard H et al. Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats. J Hypertens. 2001;(19):1233-1244. PMID: 11446713.
28. Potenza MA, Gagliardi S, De BL et al. Treatment of spontaneously hypertensive rats with rosiglitazone ameliorates cardiovascular pathophysiology via antioxidant mechanisms in the vasculature. Am J Physiol Endocrinol Metab. 2009;(297):E685-E694. doi:10.1152/ajpendo.00291.2009.
29. Ren J. Influence of gender on oxidative stress, lipid peroxidation, protein damage and apoptosis in hearts and brains from spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2007;(34):432-438. doi: 10.1111/j.1440-1681.2007.04591.x.
30. Tanito M, Nakamura H, Kwon YW et al. Enhanced oxidative stress and impaired thioredoxin expression in spontaneously hypertensive rats. Antioxid Redox Signal. 2004;(6):89-97. doi: 10.1089/152308604771978381.
31. Farmand F, Ehdaie A, Roberts CK, Sindhu RK. Lead-induced dysregulation of superoxide dismutases, catalase, glutathione peroxidase, and guanylate cyclase. Environ Res. 2005;(98):33-39. doi: 10.1016/j.envres.2004.05.016.
32. Zhan CD, Sindhu RK, Pang J, Ehdaie A, Vaziri ND. Superoxide dismutase, catalase and glutathione peroxidase in the spontaneously hypertensive rat kidney: effect of antioxidant-rich diet. J Hypertens. 2004;(22):2025-2033. PMID: 15361776.
33. Weidig P, McMaster D, Bayraktutan U. High glucose mediates pro-oxidant and antioxidant enzyme activities in coronary endothelial cells. Diabetes Obes Metab. 2004;(6):432-441. doi: 10.1111/j.1462-8902.2004.00364.x.
34. Xu S, Shriver AS, Jagadeesha DK et al. Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9. J Vasc Res. 2012;(49):242-248. doi: 10.1159/000332958.
35. Widder JD, Chen W, Li L et al. Regulation of tetrahydrobiopterin biosynthesis by shear stress. Circ Res. 2007;(101):830-838. doi:10.1161/CIRCRESAHA.107.153809.
36. Li H, Witte K, August M et al. Reversal of endothelial nitric oxide synthase uncoupling and up-regulation of endothelial nitric oxide synthase expression lowers blood pressure in hypertensive rats. J Am Coll Cardiol. 2006;(47):2536-2544. doi: 10.1016/j.jacc.2006.01.071.
37. Vaziri ND, Wang XQ, Ni ZN, Kivlighn S, Shahinfar S. Effects of aging and AT-1 receptor blockade on NO synthase expression and renal function in SHR. Biochim Biophys Acta. 2002;(1592):153-161. doi:10.1016/S0167-4889(02)00309-9.
38. Antonio RC, Ceron CS, Rizzi E et al. Antioxidant effect of doxycycline decreases MMP activity and blood pressure in SHR. Mol Cell Biochem. 2014;(386):99-105. doi: 10.1007/s11010-013-1848-7.
39. Castro MM, Rizzi E, Figueiredo-Lopes L et al. Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats. Atherosclerosis. 2008;(198):320-331. doi:10.1016/j.atherosclerosis.2007.10.011.