MicroRNA-429 functions as a regulator of epithelial-mesenchymal transition by targeting Pcdh8 during murine embryo implantation

Human Reproduction

Volumn 30, Issue 3, 2015, Pages 507-518

  Li, Zhengyu ^a   Gou, Jinhai ^a   Jia, Jia ^a   Zhao, Xia ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Embryo implantation; Epithelial mesenchymal transition; Luminal epithelium; miR 429; Pcdh8

Indexed keywords

BIOLOGICAL MARKER; CADHERIN; CADHERIN 2; LUCIFERASE; MESSENGER RNA; MICRORNA; MICRORNA 200; MICRORNA 429; PROTOCAHERIN 8; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; VIM PROTEIN; MIRN429 MICRORNA, MOUSE; PCDH8 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLASTOCYST; CONTROLLED STUDY; DECIDUALIZATION; DELAYED IMPLANTATION; DOWN REGULATION; EMBRYO; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; FERTILIZATION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LASER CAPTURE MICRODISSECTION; MALE; MARKER GENE; MOUSE; MOUSE MODEL; MULTIGENE FAMILY; NIDATION; NONHUMAN; PREGNANCY RATE; PROTEIN EXPRESSION; PSEUDOPREGNANCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY;

MURINAE; MUS;

ANIMALS; CADHERINS; EMBRYO IMPLANTATION; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MICE, INBRED C57BL; MICRORNAS;

EID: 84935124201     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dev001     Document Type: Article

References (35)

1. Chakrabarty A, Tranguch S, Daikoku T, Jensen K, Furneaux H, Dey SK. Micro RNA regulation of cyclooxygenase-2 during embryo implantation. Proc Natl Acad Sci USA 2007;104:15144-15149.
2. Chen J, Wang L, Matyunina LV, Hill CG, McDonald JF. Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells. Gynecol Oncol 2011;121:200-205.
3. Diaz-López A, Moreno-Bueno G, Cano A. Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives. Cancer Manag Res 2014;6:205-216.
4. Estella C, Herrer I, Moreno-Moya JM, Quiñonero A, Martinez S, Pellicer A, Simón C. miRNA signature and Dicer requirement during human endometrial stromal decidualization in vitro. PLoS One 2012;7:e41080.
5. Geng Y, He J, Ding Y, Chen X, Zhou Y, Liu S, Liu X, Wang Y. The differential expression ofmicroRNAs between implantation sites and interimplantation sitesinearlypregnancyinmice andtheir potential functions. Reprod Sci 2014; 21:1296-1306.
6. Gumbiner BM. Regulationofcadherin-mediated adhesionin morphogenesis. Nat Rev Mol Cell Biol 2005;6:622-634.
7. Hay ED. An overview of epithelial-mesenchymal transformation. Acta Anat (Basel) 2005;154:8-20.
8. Hill L, Browne G, Tulchinsky E. ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer. Int J Cancer 2013; 132:745-754.
9. Hu SJ, Ren G, Liu JL, Zhao ZA, Yu YS, Su RW, Ma XH, Ni H, Lei W, Yang ZM. Micro RNA expression and regulation in mouse uterus during embryo implantation. J Biol Chem 2008;283:23473-23484.
10. Koutsaki M, Spandidos DA, Zaravinos A. Epithelial-mesenchymal transition-associated miRNAs in ovarian carcinoma, with highlight on the miR-200 family: Prognostic value and prospective role in ovarian cancer therapeutics. Cancer Lett 2014;351:173-181.
11. Li Q, Wang J, Armant DR, Bagchi MK, Bagchi IC. Calcitonin down-regulates E-cadherin expression in rodent uterine epithelium during implantation. J Biol Chem 2002;277:46447-46455.
12. Li Q, Kannan A, Wang W, Demayo FJ, Taylor RN, Bagchi MK, Bagchi IC. Bone morphogenetic protein 2 functions via a conserved signaling pathway involving Wnt4 to regulate uterine decidualization in the mouse and the human. J Biol Chem 2007;282:31725-31732.
13. Lin J, Yan X, Wang C, Guo Z, Rolfs A, Luo J. Anatomical expression patterns of delta-protocadherins in developing chicken cochlea. J Anat 2012; 221:598-608.
14. Lin J, Wang C, Redies C. Expression of multiple delta-protocadherins during feather bud formation. Gene Expr Patterns 2013;13:57-65.
15. Liu X, Gao R, Chen X, Zhang A, Yang D, Ding Y, Wang Y, He J. Possible roles of mmu-miR-141 in the endometrium of mice in early pregnancy following embryo implantation. PLoS One 2013;8:e67382.
16. Mongroo PS, Rustgi AK. The role of the miR-200 family in epithelial-mesenchymal transition. Cancer Biol Ther 2010;10:219-222.
17. Nieto MA. Epithelial plasticity: a common theme in embryonic and cancer cells. Science 2013;342:1234850.
18. Pan H, Zhu L, Deng Y, Pollard JW. Microarray analysis of uterine epithelial gene expression during the implantation window in the mouse. Endocrinology 2006;147:4904-4916.
19. Paria BC, Zhao X, Das SK, Dey SK, Yoshinaga K. Zonula occludens-1 and E-cadherin are coordinately expressed in the mouse uterus with the initiation of implantation and decidualization. Dev Biol 1999;208:488-501.
20. Shen LJ, He JL, Yang DH, Ding YB, Chen XM, Geng YQ, Liu SJ, Liu XQ, Wang YX. Mmu-microRNA-200a overexpression leads to implantation defect by targeting phosphatase and tensin homolog in mouse uterus. Reprod Sci 2013;20:1518-1528.
21. Singh H, Aplin JD. Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation. J Anat 2009;215:3-13.
22. Strehl S, Glatt K, Liu QM, Glatt H, Lalande M. Characterization of two novel protocaherins(PCDH8 and PCDH9) localizedon human chromo some 13 and mouse chromosome 14. Genomics 1998;53:81-89.
23. Strickland S, Richards WG. Invasion of the trophoblasts. Cell 1992; 71:355-357.
24. Su L, Liu R, Cheng W, Zhu M, Li X, Zhao S, Yu M. Expression patterns of microRNAs in porcine endometrium and their potential roles in embryo implantation and placentation. PLoS One 2014; 9:e87867.
25. Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009;139:871-890.
26. Tse JC, Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumour microenvironment. J Cell Biochem 2007;101:816-829.
27. Uchida H, Maruyama T, Nishikawa-Uchida S, Oda H, Miyazaki K, Yamasaki A, Yoshimura Y. Studiesusinganin vitro modelshowevidenceofinvolvement of epithelial-mesenchymal transition of human endometrial epithelial cells in human embryo implantation. J Biol Chem 2012;287:4441-4450.
28. Wang L, Mezencev R, Svajdler M, Benigno BB, McDonald JF. Ectopic over-expression of miR-429 induces mesenchymal-epithelial transition (MET) and increased drug sensitivity in metastasizing ovarian cancer cells. Gynecol Oncol 2014;134:96-103.
29. Wendt MK, Allington TM, Schiemann WP. Mechanisms of the epithelial-mesenchymal transition by TGF-beta. Future Oncol 2009;5:1145-1168.
30. Xia HF, Cao JL, Jin XH, Ma X. Mi R199a is implicated in embryo implantation by regulating Grb10 in rat. Reproduction 2013;147:91-99.
31. Xia HF, Jin XH, Cao ZF, Hu Y, Ma X. Micro RNA expression and regulation in the uterus during embryo implantation in rat. FEBS J 2014a; 281:1872-1891.
32. Xia HF, Jin XH, Cao ZF, Shi T, Ma X. Mi R-98 is involved in rat embryo implantation by targeting Bcl-xl. FEBS Lett 2014b;588:574-583.
33. Yamamoto A, Kemp C, Bachiller D, Geissert D, De Robertis EM. Mouse paraxial protocadherin is expressed in trunk mesoderm and is not essential for mouse development. Genesis 2000;27:49-57.
34. Yao G, Liang M, Liang N, Yin M, Lu M, Lian J, Wang Y, Sun F. Micro RNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3. Mol Cell Endocrinol 2014;382:244-253.
35. Yishino H, Enokida H, Itesako T, Tatarano S, Kinoshita T, Fuse M, Kojima S, Nakagawa M, Seki N. Epithelial-mesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma. J Hum Genet 2013;58:508-516.