Pregnancy Does Not Attenuate the Antibody or Plasmablast Response to Inactivated Influenza Vaccine

Journal of Infectious Diseases

Volumn 212, Issue 6, 2015, Pages 861-870

  Kay, Alexander W ^a   Bayless, Nicholas L ^b   Fukuyama, Julia ^c   Aziz, Natali ^a   Dekker, Cornelia L ^a   Mackey, Sally ^a   Swan, Gary E ^b   Davis, Mark M ^a,b   Blish, Catherine A ^b  

^a Department of Pediatrics ^*  (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

hemagglutinin inhibition; influenza; plasmablast; pregnancy; vaccination; viral neutralization

Indexed keywords

HEMAGGLUTINATION INHIBITING ANTIBODY; IMMUNOGLOBULIN G; INFLUENZA VACCINE; MICRONEUTRALIZATION ANTIBODY; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; INACTIVATED VACCINE; LEUKOCYTE ANTIGEN; MEMBRANE ANTIGEN; VIRUS ANTIBODY;

ADULT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; FEMALE; HEMAGGLUTINATION INHIBITION TEST; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFLUENZA; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; LYMPHOCYTOPOIESIS; OBSERVATIONAL STUDY; PLASMABLAST; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; SEROCONVERSION; VIRUS NEUTRALIZATION; B LYMPHOCYTE; BLOOD; CASE CONTROL STUDY; COHORT ANALYSIS; CYTOLOGY; IMMUNOLOGY; INFLUENZA, HUMAN; PLASMA CELL; PREGNANCY COMPLICATIONS, INFECTIOUS; SERODIAGNOSIS; YOUNG ADULT;

ADULT; ANTIBODIES, VIRAL; ANTIGENS, CD; ANTIGENS, SURFACE; B-LYMPHOCYTES; BIOMARKERS; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HEMAGGLUTINATION INHIBITION TESTS; HUMANS; IMMUNOGLOBULIN G; INFLUENZA VACCINES; INFLUENZA, HUMAN; NEUTRALIZATION TESTS; PLASMA CELLS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; VACCINES, INACTIVATED; YOUNG ADULT;

EID: 84935098231     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv138     Document Type: Article

References (50)

1. Kourtis AP, Read JS, Jamieson DJ. Pregnancy and infection. N Engl J Med 2014; 370:2211-8.
2. Gabriel G, Arck PC. Sex, immunity and influenza. J Infect Dis 2014; 209 (Suppl 3):S93-9.
3. Harris JW. Influenza occurring in pregnant women: a statistical study of thirteen hundred and fifty cases. JAMA 1919; 72:978-80.
4. Jamieson DJ, Honein MA, Rasmussen SA, et al. Articles. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet 2009; 374:451-8.
5. Siston AM, Rasmussen SA, Honein MA, et al. Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States. JAMA 2010; 303:1517-25.
6. Louie JK, Jean C, Acosta M, Samuel MC, Matyas BT, Schechter R. A review of adult mortality due to 2009 pandemic (H1N1) influenza A in California. PLOS One 2011; 6:e18221.
7. Neuzil KM, Reed GW, Mitchel EF, Simonsen L, Griffin MR. Impact of influenza on acute cardiopulmonary hospitalizations in pregnant women. Am J Epidemiol 1998; 148:1094-102.
8. Dodds L, McNeil SA, Fell DB, et al. Impact of influenza exposure on rates of hospital admissions and physician visits because of respiratory illness among pregnant women. Can Med Assoc J 2007; 176:463-8.
9. Munoz FM. Safety of influenza vaccines in pregnant women. Am J Obstet Gynecol 2012; 207:S33-7.
10. Centers for Disease Control and Prevention. Prevention and control of seasonal influenza with vaccines. Recommendations of the Advisory Committee on Immunization Practices-United States, 2013-2014. MMWR Recomm Rep 2013; 62:1.
11. Eick AA, Uyeki TM, Klimov A, et al. Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch Pediatr Adolesc Med 2011; 165:104-11.
12. Poehling KA, Szilagyi PG, Staat MA, et al. Impact of maternal immunization on influenza hospitalizations in infants. Am J Obstet Gynecol 2011; 204:S141-8.
13. Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal influenza immunization in mothers and infants. N Engl J Med 2008; 359:1555-64.
14. Benowitz I, Esposito DB, Gracey KD, Shapiro ED, Vázquez M. Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants. Clin Infect Dis 2010; 51:1355-61.
15. Murray DL, Imagawa DT, Okada DM, St Geme JW. Antibody response to monovalent A/New Jersey/8/76 influenza vaccine in pregnant women. J Clin Microbiol 1979; 10:184-7.
16. Hulka JF. Effectiveness of polyvalent influenza vaccine in pregnancy. Report of a controlled study during an outbreak of Asian influenza. Obstet Gynecol 1964; 23:830-7.
17. Jackson LA, Patel SM, Swamy GK, et al. Immunogenicity of an inactivated monovalent 2009 H1N1 influenza vaccine in pregnant women. J Infect Dis 2011; 204:854-63.
18. Sperling RS, Engel SM, Wallenstein S, et al. Immunogenicity of trivalent inactivated influenza vaccination received during pregnancy or postpartum. Obstet Gynecol 2012; 119:631-9.
19. Schlaudecker EP, McNeal MM, Dodd CN, Ranz JB, Steinhoff MC. Pregnancy modifies the antibody response to trivalent influenza immunization. J Infect Dis 2012; 206:1670-3.
20. Gross PA, Davis AE. Neutralization test in influenza: use in individuals without hemagglutination inhibition antibody. J Clin Microbiol 1979; 10:382-4.
21. Grund S, Adams O, Wählisch S, Schweiger B. Comparison of hemagglutination inhibition assay, an ELISA-based micro-neutralization assay and colorimetric microneutralization assay to detect antibody responses to vaccination against influenza A H1N1 2009 virus. J Virol Methods 2011; 171:369-73.
22. Kilbourne ED. Comparative efficacy of neuraminidase-specific and conventional influenza virus vaccines in induction of antibody to neuraminidase in humans. J Infect Dis 1976; 134:384-94.
23. Benne CA, Kroon FP, Harmsen M, Tavares L, Kraaijeveld CA, De Jong JC. Comparison of neutralizing and hemagglutination-inhibiting antibody responses to influenza A virus vaccination of human immunodeficiency virus-infected individuals. Clin Diagn Lab Immunol 1998; 5:114-7.
24. Rowe T, Abernathy RA, Hu-Primmer J, et al. Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays. J Clin Microbiol 1999; 37:937-43.
25. Amino N, Tanizawa O, Miyai K. Changes of serum immunoglobulins IgG, IgA, IgM, and IgE during pregnancy. Obstet Gynecol 1978; 52:415-20.
26. Wrammert J, Smith K, Miller J, et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature 2008; 453:667-71.
27. Sasaki S, Sullivan M, Narvaez CF, et al. Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies. J Clin Invest 2011; 121:3109.
28. Kay AW, Fukuyama J, Aziz N, et al. Enhanced natural killer-cell and T-cell responses to influenza A virus during pregnancy. Proc Natl Acad Sci USA 2014; 111:14506-11.
29. Defang GN, Martin NJ, Burgess TH, et al. Comparative analysis of hemagglutination inhibition titers generated using temporally matched serum and plasma samples. PLOS One 2012; 7:e48229.
30. Jegaskanda S, Weinfurter JT, Friedrich TC, Kent SJ. Antibody-dependent cellular cytotoxicity is associated with control of pandemic H1N1 influenza virus infection of macaques. J Virol 2013; 87:5512-22.
31. Black S, Nicolay U, Vesikari T, et al. Hemagglutination inhibition antibody titers as a correlate of protection for inactivated influenza vaccines in children. Pediatr Infect Dis J 2011; 30:1081-5.
32. World Health Organization. Serological diagnosis of influenza by microneutralization assay. Geneva, Switzerland: World Health Organization, 2010. http://www.who.int/influenza/gisrs-laboratory/2010-12-06-serological-diagnosis-of-influenza-by-microneutralization-assay.pdf. Accessed 25 September 2013.
33. + T cell phenotypes. Immunity 2012; 36:142-52.
34. Bendall SC, Simonds EF, Qiu P, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 2011; 332:687-96.
35. Horowitz A, Strauss-Albee DM, Leipold M, et al. Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry. Sci Transl Med 2013; 5:208ra145.
36. Fienberg HG, Simonds EF, Fantl WJ, Nolan GP, Bodenmiller B. A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry A 2012; 81:467-75.
37. Finck R, Simonds EF, Jager A, et al. Normalization of mass cytometry data with bead standards. Cytometry A 2013; 83:483-94.
38. Team RC. R: A Language and Environment for Statistical Computing. Vienna, Austria, 2013.
39. Bentebibel SE, Lopez S, Obermoser G, et al. Induction of ICOS-+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination. Sci Trans Med 2013; 5:176ra32.
40. Hobson D, Curry RL, Beare AS, Ward-Gardner A. The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses. J Hyg (Lond) 1972; 70: 767-77.
41. Tsatsaris V. Maternal immune response and neonatal seroprotection from a single dose of a monovalent nonadjuvanted 2009 influenza A(H1N1) vaccine: a single-group trial. Ann Intern Med 2011; 155:733.
42. Kraus TA, Engel SM, Sperling RS, et al. Characterizing the pregnancy immune phenotype: results of the viral immunity and pregnancy (VIP) study. J Clin Immunol 2011; 32:300-11.
43. Centers for Disease Control and Prevention. Influenza vaccination coverage among pregnant women-United States, 2012-13 influenza season. MMWR Recomm Rep 2013; 62:777-80.
44. Kanda N, Tamaki K. Estrogen enhances immunoglobulin production by human PBMCs. J Allergy Clin Immunol 1999; 103:282-8.
45. Klein F, Halper-Stromberg A, Horwitz JA, et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature 2013; 492:118-22.
46. Tsokos GC. Systemic lupus erythematosus. N Engl J Med 2011; 365:2110-21.
47. He X-S, Sasaki S, Narvaez CF, et al. Plasmablast-derived polyclonal antibody response after influenza vaccination. J Immunol Methods 2011; 365:67-75.
48. Kunkel EJ, Butcher EC. Plasma-cell homing. Nat Rev Immunol 2003; 3:822-9.
49. Nakaya HI, Wrammert J, Lee EK, et al. Systems biology of vaccination for seasonal influenza in humans. Nat Immunol 2011; 12:786-95.
50. Steinhoff MC, Omer SB, Roy E, et al. Influenza immunization in pregnancy-antibody responses in mothers and infants. N Engl J Med 2010; 362:1644-6.