Direct but not indirect co-culture with osteogenically differentiated human bone marrow stromal cells increases RANKL/OPG ratio in human breast cancer cells generating bone metastases

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Arrigoni, Chiara ^a   De Luca, Paola ^b   Gilardi, Mara ^b   Previdi, Sara ^c   Broggini, Massimo ^c   Moretti, Matteo ^b  

^a IRCCS POLICLINICO SAN DONATO   (Italy)

^b IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Bone metastasis; Gene expression analyses; Heterotypic cell contacts; In vitro co cultures; RANKL pathway

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN;

ARTICLE; BONE MARROW STROMA CELL; BONE METASTASIS; BREAST CANCER CELL LINE; CELL AGGREGATION; CELL CULTURE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; MICROENVIRONMENT; OSTEOBLAST; PARACRINE SIGNALING; PROTEIN EXPRESSION; BONE DEVELOPMENT; BONE TUMOR; BREAST TUMOR; CELL COMMUNICATION; CELL MOTION; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; SECONDARY; TUMOR MICROENVIRONMENT;

BONE NEOPLASMS; BREAST NEOPLASMS; CELL AGGREGATION; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLULAR MICROENVIRONMENT; COCULTURE TECHNIQUES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; OSTEOPROTEGERIN; RANK LIGAND;

EID: 84935030082     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-238     Document Type: Article

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