Apoptosis-inducing effect of three medicinal plants on oral cancer cells KB and ORL-48

Scientific World Journal

Volumn 2014, Issue , 2014, Pages

  Majid, Mohd Zabidi ^a   Mohamad Zaini, Zuraiza ^a   Abdul Razak, Fathilah ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

AZADIRACHTA INDICA EXTRACT; BRUCEA EXTRACT; DNA; DNA FRAGMENT; PLANT EXTRACT; TYPHONIUM FLAGELLIFORME EXTRACT; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AZADIRACHTA INDICA; BRUCEA; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC50; IMMUNOHISTOCHEMISTRY; MEDICINAL PLANT; MOUTH CANCER; ORAL CANCER CELL LINE; TUNEL ASSAY; TYPHONIUM FLAGELLIFORME; CELL PROLIFERATION; CHEMISTRY; DNA FRAGMENTATION; DRUG EFFECTS; METABOLISM; MOUTH TUMOR; TUMOR CELL LINE;

AZADIRACHTA; AZADIRACHTA INDICA; BRUCEA; BRUCEA JAVANICA; TYPHONIUM; TYPHONIUM FLAGELLIFORME;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA FRAGMENTATION; HUMANS; INHIBITORY CONCENTRATION 50; MOUTH NEOPLASMS; PLANT EXTRACTS; PLANTS, MEDICINAL;

EID: 84934986352     PISSN: 23566140     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2014/125353     Document Type: Article

References (19)

1. D. Hanahan and R. A. Weinberg, "Thehallmarks of cancer, " Cell, vol. 100, no. 1, pp. 57-70, 2000.
2. V. Kumar, R. S. Cotran, and S. L. Robbins, Basic Pathology, WB Saunders, Philadelphia, Pa, USA, 6th edition, 2006.
3. P. Li, Y. Yin, D. Li, W. S. Kim, and G. Wu, "Amino acids and immune function, "The British Journal of Nutrition, vol. 98, no. 2, pp. 237-252, 2007.
4. J. Samy, M. Sugumaran, and L. W. Kate Lee, Herbs of Malaysia, Marshall Cavendish Sdn Bhd, Malaysia, 2009.
5. L. A. Anderson, A. Harris, and J. D. Phillipson, "Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures, " Journal of Natural Products, vol. 46, no. 3, pp. 374- 378, 1983.
6. J. Polonsky, J. Varenne, T. Prange, and C. Pascard, "Antileukaemic quassinoids: structure (X-ray analysis) of bruceine C and revised structure of bruceantinol, " Tetrahedron Letters, vol. 21, no. 19, pp. 1853-1856, 1980.
7. M. S. Mulla and T. Su, "Activity and biological effects of neem products against arthropods of medical and veterinary importance, " Journal of the American Mosquito Control Association, vol. 15, no. 2, pp. 133-152, 1999.
8. M. M. el-Shazly and E. D. el-Sharnoubi, "Toxicity of a Neem (Azadirachta indica) insecticide to certain aquatic organisms., " Journal of the Egyptian Society of Parasitology, vol. 30, no. 1, pp. 221-231, 2000.
9. B. K. Das, S. C. Mukherjee, B. B. Sahu, and G. Murjani, "Neem (Azadirachta indica) extract as an antibacterial agent against fish pathogenic bacteria, " Indian Journal of Experimental Biology, vol. 37, no. 11, pp. 1097-1100, 1999.
10. K. H. Teo and B. I. Ch'ng Beng, Cancer-YetThey Live, CACare, Penang, Malaysia, 2nd edition, 1999.
11. S. Hamid, K. P. Lim, R. B. Zain et al., "Establishment and characterization of Asian oral cancer cell lines as in vitro models to study a disease prevalent in Asia, " International Journal of Molecular Medicine, vol. 19, no. 3, pp. 453-460, 2007.
12. E. Borenfreund and J. A. Puerner, "A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90), " Journal of Tissue Culture Methods, vol. 9, no. 1, pp. 7-9, 1985.
13. A. R. Fathilah, R. Sujata, A. W. Norhanom, and M. I. Adenan, "Antiproliferative activity of aqueous extract of Piper betle L. and Psidium guajava L. on KB and HeLa cell lines, " Journal of Medicinal Plants Research, vol. 4, no. 11, pp. 987-990, 2010.
14. J. J. Cohen, "Apoptosis, " Immunology Today, vol. 14, no. 3, pp. 126-130, 1993.
15. A. H. Wyllie, J. F. R. Kerr, and A. R. Currie, "Cell death: The significance of apoptosis, " International Review of Cytology, vol. 68, pp. 251-306, 1980.
16. C.D. Bortner, N. B. E. Oldenburg, and J. A. Cidlowski, "Therole of DNA fragmentation in apoptosis, " Trends in Cell Biology, vol. 5, no. 1, pp. 21-26, 1995.
17. H. M. Chang and P. P. But, "Yadanzi, " in Pharmacology and Applications of Chinese Materia Medica. Vol II, World Scientific, Singapore, 1987.
18. F. Y. Lau, C. H. Chui, R. Gambari et al., "Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells, " International Journal of Molecular Medicine, vol. 16, no. 6, pp. 1157-1162, 2005.
19. J. Kim, E. K. Lau, L. Pan, and E. J. Carcache De Blanco, "NF-KappaB inhibitors from Brucea javanica exhibiting intracellular effects on reactive oxygen species, " Anticancer Research, vol. 30, no. 9, pp. 3295-3300, 2010.