Is dementia research ready for big data approaches?

BMC Medicine

Volumn 13, Issue 1, 2015, Pages

  Hofmann Apitius, Martin ^a  

^a FRAUNHOFER INSTITUTE FOR ALGORITHMS AND SCIENTIFIC COMPUTING SCAI   (Germany)

Author keywords

Big data; Data interoperability; Data mining; Disease mechanisms; Disease modeling; Semantic harmonization

Indexed keywords

ALZHEIMER DISEASE; BIG DATA; BIOMEDICINE; DEMENTIA; HUMAN; INFORMATION; MEDICAL RESEARCH; NONHUMAN; NOTE; PROBLEM SOLVING; BEHAVIORAL SCIENCE; BIOMEDICAL TECHNOLOGY ASSESSMENT; PROCEDURES; STATISTICS;

BIOBEHAVIORAL SCIENCES; BIOMEDICAL RESEARCH; DEMENTIA; HUMANS; STATISTICS AS TOPIC; TECHNOLOGY ASSESSMENT, BIOMEDICAL;

EID: 84934982225     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-015-0367-7     Document Type: Note

References (13)

1. Wikipedia entry on big data. http://en.wikipedia.org/wiki/Big_data . Accessed 4 May 2015.
2. Gartner Group IT glossary. http://www.gartner.com/it-glossary/big-data . Accessed 4 May 2015.
3. The Alzheimers Disease Big Data DREAM Challenge 1 website. https://www.synapse.org/#!Synapse:syn2290704 . Accessed 4 May 2015.
4. N4U - neuGRID for you expansion of neuGRID services and outreach to new user communities. https://neugrid4you.eu/ . Accessed 4 May 2015.
5. Developing a "mechanism-based taxonomy" of Alzheimer's and Parkinson's Disease. http://www.aetionomy.eu/ . Accessed 4 May 2015.
6. Alzheimer's Today The continuing symposium on Alzheimer's and dementia research, care, policy and education. http://adjresourcenter.alzdem.com/ . Accessed 4 May 2015.
7. Kodamullil AT, Younesi E, Naz M, Bagewadi S, Hofmann-Apitius M. Computable cause-and-effect models of healthy and Alzheimer's disease states and their mechanistic differential analysis. Alzheimers Dement. 2015. doi: 10.1016/j.jalz.2015.02.006 .
8. Fujita KA, Ostaszewski M, Matsuoka Y, Ghosh S, Glaab E, Trefois C, et al. Integrating pathways of Parkinson's disease in a molecular interaction map. Mol Neurobiol. 2014;49:88-102.
9. Catlett NL, Bargnesi AJ, Ungerer S, Seagaran T, Ladd W, Elliston KO, et al. Reverse causal reasoning: applying qualitative causal knowledge to the interpretation of high-throughput data. BMC Bioinformatics. 2013;14:340.
10. Access to the AETIONOMY knowledge base with curated and re-annotated data (to access the AETIONOMY knowledge base you will have to get registered first). http://aetionomy.scai.fhg.de/ .
11. Accelerating Medicines Partnership (AMP) Alzheimer's Disease Knowledge Portal. doi: 10.7303/syn2580853 https://www.synapse.org/#!Synapse:syn2580853 . Accessed 4 May 2015.
12. Alzheimer's Today The continuing symposium on Alzheimer's and dementia research, care, policy and education - Big Data featured posts. http://adjresourcenter.alzdem.com/BigData . Accessed 4 May 2015.
13. Population health sciences in the German National Center for Dementia Research (DZNE). Population Studies. http://www.dzne.de/en/research/research-areas/population-studies.html Accessed 4 May 2015.