Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 94, Issue , 2015, Pages 305-311

  Steffensen, Søren Langer ^a   Vestergaard, Merete Hedemark ^a   Groenning, Minna ^a   Alm, Martin ^b   Franzyk, Henrik ^a   Nielsen, Hanne Mørck ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b BioModics ApS   (Denmark)

Author keywords

Antibiotics; Biofilm; Drug delivery system; Hydrogel; Medical device; Poly(2 hydroxyethyl methacrylate); Sustained release

Indexed keywords

ACETIC ACID; CARBON DIOXIDE; CIPROFLOXACIN; DIMETICONE; POLYMACON; SILASTIC; SILICONE; ANTIINFECTIVE AGENT; DELAYED RELEASE FORMULATION;

ARTICLE; BACTERIAL COLONIZATION; BIOFILM; COMPOSITE MATERIAL; CONTROLLED STUDY; DRUG CONCENTRATION; DRUG SOLUBILITY; DRUG STABILITY; GLASS TRANSITION TEMPERATURE; HYDROGEL; HYDROGEL SILICONE COMPOSITE MATERIAL; MEDICAL DEVICE; NONHUMAN; POLYMERIZATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STAPHYLOCOCCUS AUREUS; SUSTAINED DRUG RELEASE; SYNTHESIS; CHEMISTRY; DELAYED RELEASE FORMULATION; DEVICE SAFETY; DEVICES; DRUG EFFECTS; DRUG RELEASE; GROWTH, DEVELOPMENT AND AGING; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; STANDARDS;

ANTI-INFECTIVE AGENTS; BIOFILMS; DELAYED-ACTION PREPARATIONS; DIMETHYLPOLYSILOXANES; DRUG LIBERATION; EQUIPMENT AND SUPPLIES; EQUIPMENT SAFETY; MICROBIAL SENSITIVITY TESTS; POLYHYDROXYETHYL METHACRYLATE; SILICONE ELASTOMERS; STAPHYLOCOCCUS AUREUS;

EID: 84934929937     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.05.014     Document Type: Article

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