Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction

ACS Chemical Biology

Volumn 10, Issue 6, 2015, Pages 1476-1484

  Wu, Xiaoqing ^a   Lan, Lan ^a   Wilson, David Michael ^a   Marquez, Rebecca T ^a   Tsao, Wei Chung ^a   Gao, Philip ^a   Roy, Anuradha ^a   Turner, Benjamin Andrew ^a   McDonald, Peter ^a   Tunge, Jon A ^a   Rogers, Steven A ^a   Dixon, Dan A ^b   Aubé, Jeffrey ^a   Xu, Liang ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUR PROTEIN; MESSENGER RNA; PROTEIN INHIBITOR; RIBONUCLEOPROTEIN; RNA BINDING PROTEIN; RNA BINDING PROTEIN 1; UNCLASSIFIED DRUG; ELAV LIKE PROTEIN 1; ELAVL1 PROTEIN, HUMAN; LUCIFERASE; MOLECULAR LIBRARY; MOLECULAR PROBE; MSI1 PROTEIN, HUMAN; NERVE PROTEIN; PROTEIN BINDING;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; FLUORESCENCE POLARIZATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN RNA BINDING; SURFACE PLASMON RESONANCE; ANTAGONISTS AND INHIBITORS; BINDING SITE; CELL LINE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DNA RESPONSIVE ELEMENT; DRUG EFFECTS; EPITHELIUM CELL; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; METABOLISM; MOLECULAR LIBRARY; MOLECULAR PROBE; PHARMACOLOGY; REPORTER GENE; SIGNAL TRANSDUCTION;

BINDING SITES; CELL LINE; CELL SURVIVAL; ELAV-LIKE PROTEIN 1; EPITHELIAL CELLS; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HCT116 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMMUNOPRECIPITATION; LUCIFERASES; MOLECULAR PROBES; NERVE TISSUE PROTEINS; PROTEIN BINDING; RESPONSE ELEMENTS; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; SURFACE PLASMON RESONANCE;

EID: 84934906771     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500851u     Document Type: Article

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