Optogenetic control of contractile function in skeletal muscle

Nature Communications

Volumn 6, Issue , 2015, Pages

  Bruegmann, Tobias ^a   Van Bremen, Tobias ^b   Vogt, Christoph C ^a   Send, Thorsten ^b   Fleischmann, Bernd K ^a   Sasse, Philipp ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ; CHANNELRHODOPSIN 2, MOUSE; RHODOPSIN;

CELL ORGANELLE; GENE EXPRESSION; MOBILIZATION; MUSCLE; NUMERICAL MODEL; RODENT; SKELETON; SPATIOTEMPORAL ANALYSIS; TECHNOLOGICAL CHANGE; VIRUS;

ACTION POTENTIAL DURATION; ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ELECTROSTIMULATION; FEMALE; GENE TRANSFER; LARYNX; LIGHT INTENSITY; MALE; MEMBRANE POTENTIAL; MEMBRANE STEADY POTENTIAL; MOUSE; MUSCLE CONTRACTION; MUSCLE EXCITATION; MUSCLE TETANIC CONTRACTION; MUSCLE TWITCH; NEUROMUSCULAR SYNAPSE; NONHUMAN; OPTOGENETICS; REPOLARIZATION; SOLEUS MUSCLE; VOCAL CORD; ANIMAL; DEPENDOPARVOVIRUS; GENETICS; LARYNX MUSCLE; LIGHT; PATHOLOGY; PHYSIOLOGY; PROCEDURES; SKELETAL MUSCLE; SKELETAL MUSCLE CELL; TRANSGENIC MOUSE;

ADENO-ASSOCIATED VIRUS; MUS; MUS MUSCULUS;

ANIMALS; DEPENDOVIRUS; ELECTRIC STIMULATION; LARYNGEAL MUSCLES; LIGHT; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; MUSCLE CONTRACTION; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; OPTOGENETICS; RHODOPSIN; VOCAL CORDS;

EID: 84934881090     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8153     Document Type: Article

References (29)

1. Nagel, G. et al. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc. Natl Acad. Sci. USA 100, 13940-13945 (2003).
2. Boyden, E. S., Zhang, F., Bamberg, E., Nagel, G. & Deisseroth, K. Millisecondtimescale, genetically targeted optical control of neural activity. Nat. Neurosci. 8, 1263-1268 (2005).
3. Gradinaru, V. et al. Targeting and readout strategies for fast optical neural control in vitro and in vivo. J. Neurosci. 27, 14231-14238 (2007).
4. Llewellyn, M. E., Thompson, K. R., Deisseroth, K. & Delp, S. L. Orderly recruitment of motor units under optical control in vivo. Nat. Med. 16, 1161-1165 (2010).
5. Bryson, J. B. et al. Optical control of muscle function by transplantation of stem cell-derived motor neurons in mice. Science 344, 94-97 (2014).
6. Towne, C., Montgomery, K. L., Iyer, S. M., Deisseroth, K. & Delp, S. L. Optogenetic control of targeted peripheral axons in freely moving animals. PLoS ONE 8, e72691 (2013).
7. Nagel, G. et al. Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr. Biol. 15, 2279-2284 (2005).
8. Asano, T., Ishizua, T. & Yawo, H. Optically controlled contraction of photosensitive skeletal muscle cells. Biotechnol. Bioeng. 109, 199-204 (2012).
9. Arrenberg, A. B., Stainier, D. Y., Baier, H. & Huisken, J. Optogenetic control of cardiac function. Science 330, 971-974 (2010).
10. Bruegmann, T. et al. Optogenetic control of heart muscle in vitro and in vivo. Nat. Methods 7, 897-900 (2010).
11. Zhang, Q. et al. Temporally and spatially controlled expression of transgenes in embryonic and adult tissues. Transgenic Res. 19, 499-509 (2010).
12. Martin-Oviedo, C. et al. Functional role of human laryngeal nerve connections. Laryngoscope 121, 2338-2343 (2011).
13. McCulloch, T. M., Van Daele, D. & Ciucci, M. R. Otolaryngology head and neck surgery: an integrative view of the larynx. Head Neck 33, S46-S53 (2011).
14. Xu, L. et al. Adeno-associated virus 9 mediated FKRP gene therapy restores functional glycosylation of alpha-dystroglycan and improves muscle functions. Mol. Ther. 21, 1832-1840 (2013).
15. Robin, G. & Allard, B. Major contribution of sarcoplasmic reticulum Ca2+ depletion during long-lasting activation of skeletal muscle. J. Gen. Physiol. 141, 557-565 (2013).
16. Gunaydin, L. A. et al. Ultrafast optogenetic control. Nat. Neurosci. 13, 387-392 (2010).
17. Klapoetke, N. C. et al. Independent optical excitation of distinct neural populations. Nat. Methods 11, 338-346 (2014).
18. Lin, J. Y., Knutsen, P. M., Muller, A., Kleinfeld, D. & Tsien, R. Y. ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation. Nat. Neurosci. 16, 1499-1508 (2013).
19. Seyed Toutounchi, S. J., Eydi, M., Golzari, S. E., Ghaffari, M. R. & Parvizian, N. Vocal cord paralysis and its etiologies: a prospective study. J. Cardiovasc. Thorac. Res. 6, 47-50 (2014).
20. Zealear, D. L. et al. Reanimation of the paralyzed human larynx with an Implantable electrical stimulation device. Laryngoscope 113, 1149-1156 (2003).
21. Plouin-Gaudon, I., Lawson, G., Jamart, J. & Remacle, M. Subtotal carbon dioxide laser arytenoidectomy for the treatment of bilateral vocal fold immobility: long-term results. Ann. Otol. Rhinol. Laryngol. 114, 115-121 (2005).
22. Danker, H. et al. Social withdrawal after laryngectomy. Eur. Arch. Otorhinolaryngol. 267, 593-600 (2010).
23. Nomura, K. et al. Bilateral motion restored to the paralyzed canine larynx with implantable stimulator. Laryngoscope 120, 2399-2409 (2010).
24. Thomas, L. B., Stemple, J. C., Andreatta, R. D. & Andrade, F. H. Establishing a new animal model for the study of laryngeal biology and disease: an anatomic study of the mouse larynx. J. Speech Lang. Hear. Res. 52, 802-811 (2009).
25. Wang, Z. J., Tapscott, S. J., Chamberlain, J. S. & Storb, R. Immunity and AAV-mediated gene therapy for muscular dystrophies in large animal models and human trials. Front. Microbiol. 2, 201 (2011).
26. Bowles, D. E. et al. Phase 1 gene therapy for duchenne muscular dystrophy using a translational optimized AAV vector. Mol. Ther. 20, 443-455 (2012).
27. Mendell, J. R. et al. Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D. Ann. Neurol. 68, 629-638 (2010).
28. Tallis, J., James, R. S., Cox, V. M. & Duncan, M. J. The effect of physiological concentrations of caffeine on the power output of maximally and submaximally stimulated mouse EDL (fast) and soleus (slow) muscle. J. Appl. Physiol. 112, 64-71 (2012).
29. Gonzalez, E. & Delbono, O. Age-dependent fatigue in single intact fast- and slow fibers from mouse EDL and soleus skeletal muscles. Mech. Ageing Dev. 122, 1019-1032 (2001).