Nanocarriers for photodynamic therapy - Rational formulation design and medium-scale manufacture

International Journal of Pharmaceutics

Volumn 491, Issue 1-2, 2015, Pages 250-260

  Villa Nova, Mônica ^a   Janas, Christine ^b   Schmidt, Mike ^c   Ulshoefer, Thomas ^c   Gräfe, Susanna ^d   Schiffmann, Susanne ^c   De Bruin, Natasja ^d   Wiehe, Arno ^d   Albrecht, Volker ^d   Parnham, Michael J ^c   Bruschi, Marcos Luciano ^a   Wacker, Matthias G ^c  

^a Laboratory of RandD of Drug Delivery Systems Postgraduate Program in Pharmaceutical Sciences Department of Pharmacy   (Brazil)

^b GOETHE UNIVERSITY   (Germany)

^c FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^d Biolitec Research GmbH   (Germany)

Author keywords

Experimental design; Microreactor technology; mTHPC; Photodynamic therapy; Photosensitizer; PLGA PEG

Indexed keywords

NANOCARRIER; POLYGLACTIN; TEMOPORFIN; DRUG CARRIER; MACROGOL DERIVATIVE; MESOPORPHYRIN; METHOXYPOLYETHYLENEGLYCOL-POLY(LACTIC-CO-GLYCOLIC ACID); NANOMATERIAL; PHOTOSENSITIZING AGENT; POLYESTER;

ANIMAL EXPERIMENT; ARTICLE; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG RELEASE; FACTORIAL DESIGN; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MICROFLUIDICS; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PREFORMULATION; PRIORITY JOURNAL; QUALITY CONTROL; SCALE UP; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG INDUSTRY; INTRAVENOUS DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; MICROFLUIDIC ANALYSIS; PHOTOCHEMOTHERAPY; PROCEDURES; TISSUE DISTRIBUTION;

ADMINISTRATION, INTRAVENOUS; ANIMALS; CELL LINE; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DESIGN; DRUG INDUSTRY; HUMANS; MESOPORPHYRINS; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; NANOSTRUCTURES; PARTICLE SIZE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POLYESTERS; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION;

EID: 84934762898     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.06.024     Document Type: Article

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