Adsorption of plasma proteins on uncoated PLGA nanoparticles

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 85, Issue 1, 2013, Pages 53-60

  Sempf, Karim ^a   Arrey, Tabiwang ^a   Gelperina, Svetlana ^b   Schorge, Tobias ^a   Meyer, Björn ^a   Karas, Michael ^a   Kreuter, Jörg ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Nanosystem LTD   (Russian Federation)

Author keywords

2D PAGE; HDL; MALDI TOF TOF; Mass spectrometry; Plasma proteins; Poly(lactide co glycolide) (PLGA) nanoparticles; Trypsin

Indexed keywords

APOLIPOPROTEIN E; DODECYL SULFATE SODIUM; DOXORUBICIN; GLYCOPROTEIN; HIGH DENSITY LIPOPROTEIN; HISTIDINE RICH GLYCOPROTEIN; KININOGEN; KININOGEN I; NANOPARTICLE; PLASMA PROTEIN; POLYGLACTIN; POLYGLACTIN NANOPARTICLE; TRYPSIN; UNCLASSIFIED DRUG; VITRONECTIN; WATER;

ADSORPTION KINETICS; ANALYTIC METHOD; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HUMAN; INCUBATION TIME; LIQUID CHROMATOGRAPHY; MASCOT SCORE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PARTICLE SIZE; PLASMA; PROTEIN LOCALIZATION; SCORING SYSTEM; TWO DIMENSIONAL GEL ELECTROPHORESIS;

2D-PAGE; HDL; MALDI-TOF/TOF; MASS SPECTROMETRY; PLASMA PROTEINS; POLY(LACTIDE-CO-GLYCOLIDE) (PLGA) NANOPARTICLES; TRYPSIN;

ADSORPTION; APOLIPOPROTEINS E; BLOOD BANKS; BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATABASES, PROTEIN; DRUG CARRIERS; FEASIBILITY STUDIES; HUMANS; KININOGENS; LACTIC ACID; LIPOPROTEINS, HDL; MICROCHEMISTRY; NANOPARTICLES; PEPTIDE MAPPING; POLYGLYCOLIC ACID; PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SURFACE PROPERTIES; TANDEM MASS SPECTROMETRY; VITRONECTIN;

EID: 84882810977     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.11.030     Document Type: Article

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