Effects of Proanthocyanidins on Adhesion, Growth, and Virulence of Highly Virulent Extraintestinal Pathogenic Escherichia coli Argue for Its Use to Treat Oropharyngeal Colonization and Prevent Ventilator-Associated Pneumonia

Critical Care Medicine

Volumn 43, Issue 6, 2015, Pages e170-e178

  Margetis, Dimitri ^a,b,c   Roux, Damien ^a,b,c   Gaudry, Stéphane ^a,b,c   Messika, Jonathan ^a,b,c   Bouvet, Odile ^a,b   Branger, Catherine ^a,b,c   Ponnuswamy, Padmapriya ^a,b   Oufella, Hafid Ait ^a,b   Dreyfuss, Didier ^a,b,c   Denamur, Erick ^a,b   Ricard, Jean Damien ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL LOUIS MOURIER   (France)

Author keywords

adhesion; antimicrobial resistance; Escherichia coli; nosocomial infections; oropharyngeal colonization; proanthocyanidin; ventilator associated pneumonia

Indexed keywords

ANTIBIOTIC AGENT; CRANBERRY PROANTHOCYANIDIN; PROANTHOCYANIDIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CONTROLLED STUDY; CRANBERRY; DRUG EFFECT; EPITHELIUM CELL; EXTRAINTESTINAL PATHOGENIC ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LUNG BACTERIAL COUNT; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NORMAL HUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PULMONARY IMMUNE RESPONSE; RESPIRATORY TRACT PARAMETERS; VENTILATOR ASSOCIATED PNEUMONIA; ANIMAL; BAGG ALBINO MOUSE; CRITICAL ILLNESS; DOSE RESPONSE; DRUG EFFECTS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GROWTH, DEVELOPMENT AND AGING; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY;

ANIMALS; BACTERIOLOGICAL TECHNIQUES; BRONCHOALVEOLAR LAVAGE FLUID; CRITICAL ILLNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; MALE; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; PROANTHOCYANIDINS; VACCINIUM MACROCARPON;

EID: 84934451276     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000972     Document Type: Article

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