Cranberries vs antibiotics to prevent urinary tract infections: A randomized double-blind noninferiority trial in premenopausal women

Archives of Internal Medicine

Volumn 171, Issue 14, 2011, Pages 1270-1278

  Beerepoot, Mariëlle A J ^a   Ter Riet, Gerben ^a   Nys, Sita ^b   Van Der Wal, Willem M ^c   De Borgie, Corianne A J M ^a   De Reijke, Theo M ^a   Prins, Jan M ^a   Koeijers, Jeanne ^b   Verbon, Annelies ^d   Stobberingh, Ellen ^b   Geerlings, Suzanne E ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CIPROFLOXACIN; COTRIMOXAZOLE; CRANBERRY EXTRACT; TRIMETHOPRIM;

ADULT; ANKLE PAIN; ANTIBIOTIC RESISTANCE; ARTHRALGIA; ARTICLE; BACTERIUM ISOLATE; BACTERIURIA; CONSTIPATION; CRANBERRY; DIARRHEA; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG CAPSULE; DRUG EFFICACY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ESCHERICHIA COLI; FATIGUE; FEMALE; HEADACHE; HUMAN; INFECTION PREVENTION; MAJOR CLINICAL STUDY; MYALGIA; NAUSEA; PATIENT COMPLIANCE; PHOTOSENSITIVITY; PREMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; RECURRENT INFECTION; STEVENS JOHNSON SYNDROME; URINARY TRACT INFECTION; URTICARIA; VAGINA CANDIDIASIS; VOMITING;

ADULT; AMOXICILLIN; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS, URINARY; CAPSULES; CIPROFLOXACIN; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS; MIDDLE AGED; PLANT PREPARATIONS; PREMENOPAUSE; RECURRENCE; TREATMENT OUTCOME; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION; URINARY TRACT INFECTIONS; VACCINIUM MACROCARPON;

EID: 79960956720     PISSN: 00039926     EISSN: 15383679     Source Type: Journal    
DOI: 10.1001/archinternmed.2011.306     Document Type: Article

References (25)

1. Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon. 2003;49(2):53-70. (Pubitemid 36350775)
2. Hooton TM. Recurrent urinary tract infection in women. Int J Antimicrob Agents. 2001;17(4):259-268. (Pubitemid 32288741)
3. Murray BE, Rensimer ER, DuPont HL. Emergence of high-level trimethoprim resistance in fecal Escherichia coli during oral administration of trimethoprim or trimethoprim-sulfamethoxazole. N Engl J Med. 1982;306(3):130-135. (Pubitemid 12165778)
4. Gupta K. Emerging antibiotic resistance in urinary tract pathogens. Infect Dis Clin North Am. 2003;17(2):243-259. (Pubitemid 36760182)
5. Howell AB, Botto H, Combescure C, et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. BMC Infect Dis. 2010;10:94. doi:10.1186/1471- 2334-10-94.
6. Raz R, Chazan B, Dan M. Cranberry juice and urinary tract infection. Clin Infect Dis. 2004;38(10):1413-1419. (Pubitemid 38668589)
7. Guay DR. Cranberry and urinary tract infections. Drugs. 2009;69(7):775-807.
8. Jepson RG, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev. 2008;(1):CD001321.
9. Barbosa-Cesnik C, Brown MB, Buxton M, Zhang L, DeBusscher J, Foxman B. Cranberry juice fails to prevent recurrent urinary tract infection: results from a randomized placebo-controlled trial. Clin Infect Dis. 2011;52(1):23-30.
10. Aston JL, Lodolce AE, Shapiro NL. Interaction between warfarin and cranberry juice. Pharmacotherapy. 2006;26(9):1314-1319. (Pubitemid 44313758)
11. Terris MK, Issa MM, Tacker JR. Dietary supplementation with cranberry concentrate tablets may increase the risk of nephrolithiasis. Urology. 2001;57(1):26-29.
12. Howell AB, Foxman B. Cranberry juice and adhesion of antibiotic-resistant uropathogens. JAMA. 2002;287(23):3082-3083. (Pubitemid 34633981)
13. Gu L, House SE, Wu X, Ou B, Prior RL. Procyanidin and catechin contents and antioxidant capacity of cocoa and chocolate products. J Agric Food Chem. 2006;54(11):4057-4061. (Pubitemid 44030590)
14. Neal DE Jr. Complicated urinary tract infections. Urol Clin North Am. 2008;35(1):13-22, v.
15. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing. 7th ed. Wayne, PA: CLSI; 2009. Report M7-A7.
16. Liu YC, Huang WK, Huang TS, Kunin CM. Detection of antimicrobial activity in urine for epidemiologic studies of antibiotic use. J Clin Epidemiol. 1999;52(6):539-545. (Pubitemid 29281672)
17. Little P, Turner S, Rumsby K, et al. Developing clinical rules to predict urinary tract infection in primary care settings: sensitivity and specificity of near patient tests (dipsticks) and clinical scores. Br J Gen Pract. 2006;56(529):606-612. (Pubitemid 44209984)
18. Piaggio G, Elbourne DR, Altman DG, Pocock SJ, Evans SJ; CONSORT Group. Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA. 2006;295(10):1152-1160. (Pubitemid 43352345)
19. Cole SR, Hernán MA. Constructing inverse probability weights for marginal structural models. Am J Epidemiol. 2008;168(6):656-664.
20. Fihn SD. Acute uncomplicated urinary tract infection in women. N Engl J Med. 2003;349(3):259-266. (Pubitemid 36859478)
21. Bent S, Saint S. The optimal use of diagnostic testing in women with acute uncomplicated cystitis. Dis Mon. 2003;49(2):83-98. (Pubitemid 36350777)
22. Hooton TM, Scholes D, Hughes JP, et al. A prospective study of risk factors for symptomatic urinary tract infection in young women. N Engl J Med. 1996;335(7):468-474. (Pubitemid 26269946)
23. Prior RL, Fan E, Ji H, et al. Multi-laboratory validation of a standard method for quantifying proanthocyanidins in cranberry powders. J Sci Food Agric. 2010;90(9):1473-1478.
24. McMurdo ME, Argo I, Phillips G, Daly F, Davey P. Cranberry or trimethoprim for the prevention of recurrent urinary tract infections? a randomized controlled trial in older women. J Antimicrob Chemother. 2009;63(2):389-395.
25. Kahlmeter G, Menday P. Cross-resistance and associated resistance in 2478 Escherichia coli isolates from the pan-European ECO.SENS Project surveying the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections. J Antimicrob Chemother. 2003;52(1):128-131. (Pubitemid 36850099)