-
1
-
-
7944236785
-
Src family kinases, key regulators of signal transduction
-
DOI 10.1038/sj.onc.1208160
-
Parsons SJ, Parsons JT (2004) Src family kinases, key regulators of signal transduction. Oncogene 23: 7906-7909. (Pubitemid 39468849)
-
(2004)
Oncogene
, vol.23
, Issue.48 REV. ISS. 7
, pp. 7906-7909
-
-
Parsons, S.J.1
Parsons, J.T.2
-
3
-
-
2942618768
-
A renaissance for SRC
-
Yeatman TJ (2004) A renaissance for SRC. Nat Rev Cancer 4: 470-480.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 470-480
-
-
Yeatman, T.J.1
-
4
-
-
0032875098
-
Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
-
Resh MD (1999) Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim Biophys Acta 1451: 1-16.
-
(1999)
Biochim Biophys Acta
, vol.1451
, pp. 1-16
-
-
Resh, M.D.1
-
5
-
-
7944223078
-
Structure and regulation of Src family kinases
-
DOI 10.1038/sj.onc.1208081
-
Boggon TJ, Eck MJ (2004) Structure and regulation of Src family kinases. Oncogene 23: 7918-7927. (Pubitemid 39468851)
-
(2004)
Oncogene
, vol.23
, Issue.48 REV. ISS. 7
, pp. 7918-7927
-
-
Boggon, T.J.1
Eck, M.J.2
-
6
-
-
29144452123
-
Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases
-
DOI 10.1016/j.bbapap.2005.07.027, PII S1570963905002864
-
Chong YP, Ia KK, Mulhern TD, Cheng HC (2005) Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases. Biochim Biophys Acta 1754: 210-220. (Pubitemid 41797700)
-
(2005)
Biochimica et Biophysica Acta - Proteins and Proteomics
, vol.1754
, Issue.1-2
, pp. 210-220
-
-
Chong, Y.-P.1
Ia, K.K.2
Mulhern, T.D.3
Cheng, H.-C.4
-
7
-
-
0033063429
-
Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
-
DOI 10.1016/S1097-2765(00)80357-3
-
Schindler T, Sicheri F, Pico A, Gazit A, Levitzki A, et al. (1999) Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor. Mol Cell 3: 639-648. (Pubitemid 29268447)
-
(1999)
Molecular Cell
, vol.3
, Issue.5
, pp. 639-648
-
-
Schindler, T.1
Sicheri, F.2
Pico, A.3
Gazit, A.4
Levitzki, A.5
Kuriyan, J.6
-
8
-
-
0033001789
-
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
-
DOI 10.1016/S1097-2765(00)80356-1
-
Xu W, Doshi A, Lei M, Eck MJ, Harrison SC (1999) Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol Cell 3: 629-638. (Pubitemid 29268446)
-
(1999)
Molecular Cell
, vol.3
, Issue.5
, pp. 629-638
-
-
Xu, W.1
Doshi, A.2
Lei, M.3
Eck, M.J.4
Harrison, S.C.5
-
9
-
-
0031034930
-
Crystal structure of the Src family tyrosine kinase Hck
-
DOI 10.1038/385602a0
-
Sicheri F, Moarefi I, Kuriyan J (1997) Crystal structure of the Src family tyrosine kinase Hck. Nature 385: 602-609. (Pubitemid 27087567)
-
(1997)
Nature
, vol.385
, Issue.6617
, pp. 602-609
-
-
Sicheri, F.1
Moarefi, I.2
Kuriyan, J.3
-
10
-
-
0031025991
-
Three-dimensional structure of the tyrosine kinase c-Src
-
DOI 10.1038/385595a0
-
Xu W, Harrison SC, Eck MJ (1997) Three-dimensional structure of the tyrosine kinase c-Src. Nature 385: 595-602. (Pubitemid 27087566)
-
(1997)
Nature
, vol.385
, Issue.6617
, pp. 595-602
-
-
Xu, W.1
Harrison, S.C.2
Eck, M.J.3
-
11
-
-
0033543694
-
SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in rat-2 fibroblasts
-
Briggs SD, Smithgall TE (1999) SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in rat-2 fibroblasts. J Biol Chem 274: 26579-26583.
-
(1999)
J Biol Chem
, vol.274
, pp. 26579-26583
-
-
Briggs, S.D.1
Smithgall, T.E.2
-
12
-
-
0029896163
-
Regulation, substrates, and functions of Src
-
Brown MT, Cooper JA (1996) Regulation, substrates, and functions of Src. Biochim Biophys Acta 1287: 121-149.
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
13
-
-
0031962265
-
SH2- and SH3-mediated interactions between focal adhesion kinase and Src
-
DOI 10.1074/jbc.273.1.577
-
Thomas JW, Ellis B, Boerner RJ, Knight WB, White GC, et al. (1998) SH2- and SH3-mediated interactions between focal adhesion kinase and Src. J Biol Chem 273: 577-583. (Pubitemid 28042247)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.1
, pp. 577-583
-
-
Thomas, J.W.1
Ellis, B.2
Boerner, R.J.3
Knight, W.B.4
White II, G.C.5
Schaller, M.D.6
-
14
-
-
0031017838
-
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement
-
DOI 10.1038/385650a0
-
Moarefi I, LaFevre-Bernt M, Sicheri F, Huse M, Lee C-H, et al. (1997) Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement. Nature 385: 650-653. (Pubitemid 27087580)
-
(1997)
Nature
, vol.385
, Issue.6617
, pp. 650-653
-
-
Moarefi, I.1
LaFevre-Bernt, M.2
Sicheri, F.3
Huse, M.4
Lee, C.-H.5
Kuriyan, J.6
Miller, W.T.7
-
15
-
-
0030792141
-
SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1
-
DOI 10.1074/jbc.272.29.17899
-
Briggs SD, Sharkey M, Stevenson M, Smithgall TE (1997) SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1. J Biol Chem 272: 17899-17902. (Pubitemid 27306363)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.29
, pp. 17899-17902
-
-
Briggs, S.D.1
Sharkey, M.2
Stevenson, M.3
Smithgall, T.E.4
-
16
-
-
73349084621
-
Chemical genetics identifies c-Src as an activator of primitive ectoderm formation in murine embryonic stem cells
-
Meyn MA, III, Smithgall TE (2009) Chemical genetics identifies c-Src as an activator of primitive ectoderm formation in murine embryonic stem cells. Sci Signal 2: ra64.
-
(2009)
Sci Signal
, vol.2
-
-
Meyn III, M.A.1
Smithgall, T.E.2
-
17
-
-
3843055775
-
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal
-
DOI 10.1074/jbc.M403547200
-
Anneren C, Cowan CA, Melton DA (2004) The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. J Biol Chem 279: 31590-31598. (Pubitemid 39037828)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31590-31598
-
-
Anneren, C.1
Cowan, C.A.2
Melton, D.A.3
-
18
-
-
84900400146
-
c-Yes Tyrosine Kinase Is a Potent Suppressor of ES Cell Differentiation and Antagonizes the Actions of Its Closest Phylogenetic Relative, c-Src
-
Zhang X, Meyn MA, III, Smithgall TE (2013) c-Yes Tyrosine Kinase Is a Potent Suppressor of ES Cell Differentiation and Antagonizes the Actions of Its Closest Phylogenetic Relative, c-Src. ACS Chem Biol 9: 139-146.
-
(2013)
ACS Chem Biol
, vol.9
, pp. 139-146
-
-
Zhang, X.1
Meyn III, M.A.2
Smithgall, T.E.3
-
19
-
-
79952081456
-
Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells
-
Sancier F, Dumont A, Sirvent A, Paquay de PL, Edmonds T, et al. (2011) Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells. PLoS One 6: e17237.
-
(2011)
PLoS One
, vol.6
-
-
Sancier, F.1
Dumont, A.2
Sirvent, A.3
De Paquay, P.L.4
Edmonds, T.5
-
20
-
-
0028811162
-
Phage display selection of ligand residues important for Src homology 3 domain binding specificity
-
Rickles RJ, Botfield MC, Zhou XM, Henry PA, Brugge JS, et al. (1995) Phage display selection of ligand residues important for Src homology 3 domain binding specificity. Proc Natl Acad Sci U S A 92: 10909-10913.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 10909-10913
-
-
Rickles, R.J.1
Botfield, M.C.2
Zhou, X.M.3
Henry, P.A.4
Brugge, J.S.5
-
21
-
-
0029589911
-
Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands
-
DOI 10.1073/pnas.92.26.12408
-
Feng S, Kasahara C, Rickles RJ, Schreiber SL (1995) Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Proc Natl Acad Sci U S A 92: 12408-12415. (Pubitemid 26014079)
-
(1995)
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, Issue.26
, pp. 12408-12415
-
-
Feng, S.1
Kasahara, C.2
Rickles, R.J.3
Schreiber, S.L.4
-
22
-
-
28844463657
-
Activation of the Src family kinase Hck without SH3-linker release
-
DOI 10.1074/jbc.M508782200
-
Lerner EC, Trible RP, Schiavone AP, Hochrein JM, Engen JR, et al. (2005) Activation of the Src Family Kinase Hck without SH3-Linker Release. J Biol Chem 280: 40832-40837. (Pubitemid 41780575)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 40832-40837
-
-
Lerner, E.C.1
Trible, R.P.2
Schiavone, A.P.3
Hochrein, J.M.4
Engen, J.R.5
Smithgall, T.E.6
-
23
-
-
33748751555
-
HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction
-
DOI 10.1074/jbc.M601128200
-
Trible RP, Emert-Sedlak L, Smithgall TE (2006) HIV-1 Nef selectively activates SRC family kinases HCK, LYN, and c-SRC through direct SH3 domain interaction. J Biol Chem 281: 27029-27038. (Pubitemid 44401731)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.37
, pp. 27029-27038
-
-
Trible, R.P.1
Emert-Sedlak, L.2
Smithgall, T.E.3
-
24
-
-
0029559182
-
Kinetic mechanisms of the forward and reverse pp60(c-src) tyrosine kinase reactions
-
DOI 10.1021/bi00050a024
-
Boerner RJ, Barker SC, Knight WB (1995) Kinetic mechanisms of the forward and reverse pp60c-src tyrosine kinase reactions. Biochemistry 34: 16419-16423. (Pubitemid 26006487)
-
(1995)
Biochemistry
, vol.34
, Issue.50
, pp. 16419-16423
-
-
Boerner, R.J.1
Barker, S.C.2
Knight, W.B.3
-
25
-
-
0028973603
-
Characterization of pp60c-src tyrosine kinase activities using a continuous assay: Autoactivation of the enzyme is an intramolecular autophosphorylation process
-
Barker SC, Kassel DB, Weigl D, Huang X, Luther MA, et al. (1995) Characterization of pp60c-src tyrosine kinase activities using a continuous assay: autoactivation of the enzyme is an intermolecular autophosphorylation process. Biochemistry 34: 14843-14851. (Pubitemid 3002541)
-
(1995)
Biochemistry
, vol.34
, Issue.45
, pp. 14843-14851
-
-
Barker, S.C.1
Kassel, D.B.2
Weigl, D.3
Huang, X.4
Luther, M.A.5
Knight, W.B.6
-
26
-
-
24944497371
-
Features of selective kinase inhibitors
-
DOI 10.1016/j.chembiol.2005.04.011
-
Knight ZA, Shokat KM (2005) Features of selective kinase inhibitors. Chem Biol 12: 621-637. (Pubitemid 43142039)
-
(2005)
Chemistry and Biology
, vol.12
, Issue.6
, pp. 621-637
-
-
Knight, Z.A.1
Shokat, K.M.2
-
27
-
-
0027971687
-
Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries
-
Rickles RJ, Botfield MC, Weng Z, Taylor JA, Green OM, et al. (1994) Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries. EMBO J 13: 5598-5604.
-
(1994)
EMBO J
, vol.13
, pp. 5598-5604
-
-
Rickles, R.J.1
Botfield, M.C.2
Weng, Z.3
Taylor, J.A.4
Green, O.M.5
-
28
-
-
0034723419
-
Reciprocal regulation of Hck activity by phosphorylation of Tyr 527 and Tyr416: Effect of introducing a high affinity intramolecular SH2 ligand
-
DOI 10.1074/jbc.275.4.2721
-
Porter M, Schindler T, Kuriyan J, Miller WT (2000) Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand. J Biol Chem 275: 2721-2726. (Pubitemid 30082042)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.4
, pp. 2721-2726
-
-
Porter, M.1
Schindler, T.2
Kuriyan, J.3
Miller, W.T.4
-
29
-
-
0028878783
-
Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
-
Saksela K, Cheng G, Baltimore D (1995) Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. EMBO J 14: 484-491.
-
(1995)
EMBO J
, vol.14
, pp. 484-491
-
-
Saksela, K.1
Cheng, G.2
Baltimore, D.3
-
30
-
-
0034711735
-
Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo
-
DOI 10.1021/bi992504j
-
Briggs SD, Lerner EC, Smithgall TE (2000) Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo. Biochemistry: 489-495. (Pubitemid 30077622)
-
(2000)
Biochemistry
, vol.39
, Issue.3
, pp. 489-495
-
-
Briggs, S.D.1
Lerner, E.C.2
Smithgall, T.E.3
-
31
-
-
0033610850
-
Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue
-
DOI 10.1074/jbc.273.48.32129
-
LaFevre-Bernt M, Sicheri F, Pico A, Porter M, Kuriyan J, et al. (1998) Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue. Journal of Biological Chemistry 273: 32129-32134. (Pubitemid 29177157)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.48
, pp. 32129-32134
-
-
Lafevre-Bernt, M.1
Sicheri, F.2
Pico, A.3
Porter, M.4
Kuriyan, J.5
Todd, M.W.6
-
33
-
-
84874326369
-
Enhanced SH3/linker interaction overcomes Abl kinase activation by gatekeeper and myristic acid binding pocket mutations and increases sensitivity to small molecule inhibitors
-
Panjarian S, Iacob RE, Chen S, Wales TE, Engen JR, et al. (2013) Enhanced SH3/linker interaction overcomes Abl kinase activation by gatekeeper and myristic acid binding pocket mutations and increases sensitivity to small molecule inhibitors. J Biol Chem 288: 6116-6129.
-
(2013)
J Biol Chem
, vol.288
, pp. 6116-6129
-
-
Panjarian, S.1
Iacob, R.E.2
Chen, S.3
Wales, T.E.4
Engen, J.R.5
-
34
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
DOI 10.1016/j.ceb.2006.08.011, PII S0955067406001220
-
Mitra SK, Schlaepfer DD (2006) Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 18: 516-523. (Pubitemid 44332916)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.5
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
35
-
-
0028106837
-
Physical and functional association of the high affinity immunoglobulin G receptor (FcgammaRI) with the kinases Hck and Lyn
-
DOI 10.1084/jem.180.3.1165
-
Wang AV, Scholl PR, Geha RS (1994) Physical and functional association of the high-affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn. J Exp Med 180: 1165-1170. (Pubitemid 24256631)
-
(1994)
Journal of Experimental Medicine
, vol.180
, Issue.3
, pp. 1165-1170
-
-
Wang, A.V.T.1
Scholl, P.R.2
Geha, R.S.3
-
36
-
-
0034742143
-
FcgammaR-mediated phagocytosis by human macrophages involves Hck, Syk, and Pyk2 and is augmented by GM-CSF
-
Kedzierska K, Vardaxis NJ, Jaworowski A, Crowe SM (2001) FcgammaR-mediated phagocytosis by human macrophages involves Hck, Syk, and Pyk2 and is augmented by GM-CSF. J Leukoc Biol 70: 322-328. (Pubitemid 32751525)
-
(2001)
Journal of Leukocyte Biology
, vol.70
, Issue.2
, pp. 322-328
-
-
Kedzierska, K.1
Vardaxis, N.J.2
Jaworowski, A.3
Crowe, S.M.4
-
37
-
-
14844366890
-
The Fc gamma RI receptor signals through the activation of Hck and MAP kinase
-
Durden DL, Kim HM, Calore B, Liu Y (1995) The Fc gamma RI receptor signals through the activation of Hck and MAP kinase. J Immunol 154: 4039-4047.
-
(1995)
J Immunol
, vol.154
, pp. 4039-4047
-
-
Durden, D.L.1
Kim, H.M.2
Calore, B.3
Liu, Y.4
-
38
-
-
80054710649
-
Hck is a key regulator of gene expression in alternatively activated human monocytes
-
Bhattacharjee A, Pal S, Feldman GM, Cathcart MK (2011) Hck is a key regulator of gene expression in alternatively activated human monocytes. J Biol Chem 286: 36709-36723.
-
(2011)
J Biol Chem
, vol.286
, pp. 36709-36723
-
-
Bhattacharjee, A.1
Pal, S.2
Feldman, G.M.3
Cathcart, M.K.4
-
39
-
-
28844458822
-
High yield bacterial expression of active c-Abl and c-Src tyrosine kinases
-
DOI 10.1110/ps.051750905
-
Seeliger MA, Young M, Henderson MN, Pellicena P, King DS, et al. (2005) High yield bacterial expression of active c-Abl and c-Src tyrosine kinases. Protein Sci 14: 3135-3139. (Pubitemid 41770154)
-
(2005)
Protein Science
, vol.14
, Issue.12
, pp. 3135-3139
-
-
Seeliger, M.A.1
Young, M.2
Henderson, M.N.3
Pellicena, P.4
King, D.S.5
Falick, A.M.6
Kuriyan, J.7
-
40
-
-
60849134578
-
Conformational disturbance in Abl kinase upon mutation and deregulation
-
Iacob RE, Pene-Dumitrescu T, Zhang J, Gray NS, Smithgall TE, et al. (2009) Conformational disturbance in Abl kinase upon mutation and deregulation. Proc Natl Acad Sci U S A 106: 1386-1391.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1386-1391
-
-
Iacob, R.E.1
Pene-Dumitrescu, T.2
Zhang, J.3
Gray, N.S.4
Smithgall, T.E.5
-
41
-
-
33744912806
-
A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 59-diphosphate accumulation
-
DOI 10.1177/1087057106286829
-
Charter NW, Kauffman L, Singh R, Eglen RM (2006) A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 59-diphosphate accumulation. J Biomol Screen 11: 390-399. (Pubitemid 43846339)
-
(2006)
Journal of Biomolecular Screening
, vol.11
, Issue.4
, pp. 390-399
-
-
Charter, N.W.1
Kauffman, L.2
Singh, R.3
Eglen, R.M.4
-
42
-
-
0029046713
-
Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases
-
Lam KS, Wu J, Lou Q (1995) Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases. Int J Pept Protein Res 45: 587-592.
-
(1995)
Int J Pept Protein Res
, vol.45
, pp. 587-592
-
-
Lam, K.S.1
Wu, J.2
Lou, Q.3
-
43
-
-
0029758089
-
Correlation of the phosphorylation states of pp60(c-src) with tyrosine kinase activity: The intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated
-
DOI 10.1021/bi960248u
-
Boerner RJ, Kassel DB, Barker SC, Ellis B, DeLacy P, et al. (1996) Correlation of the phosphorylation states of pp60c-src with tyrosine kinase activity: the intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated. Biochemistry 35: 9519-9525. (Pubitemid 26320059)
-
(1996)
Biochemistry
, vol.35
, Issue.29
, pp. 9519-9525
-
-
Boerner, R.J.1
Kassel, D.B.2
Barker, S.C.3
Ellis, B.4
DeLacy, P.5
Knight, W.B.6
-
44
-
-
33745777632
-
UPLC/MSE; a new approach for generating molecular fragment information for biomarker structure elucidation
-
DOI 10.1002/rcm.2550
-
Plumb RS, Johnson KA, Rainville P, Smith BW, Wilson ID, et al. (2006) UPLC/MS(E); a new approach for generating molecular fragment information for biomarker structure elucidation. Rapid Commun Mass Spectrom 20: 1989-1994. (Pubitemid 44024575)
-
(2006)
Rapid Communications in Mass Spectrometry
, vol.20
, Issue.13
, pp. 1989-1994
-
-
Plumb, R.S.1
Johnson, K.A.2
Rainville, P.3
Smith, B.W.4
Wilson, I.D.5
Castro-Perez, J.M.6
Nicholson, J.K.7
|