The PANDAS syndrome

Advances in Experimental Medicine and Biology

Volumn 634, Issue , 2009, Pages 205-216

  Pichichero, Michael E ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISTREPTOLYSIN; AUTOANTIBODY; AZITHROMYCIN; PENICILLIN V;

ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; ATTENTION DISTURBANCE; BACTERIUM CULTURE; CHOREA; CLINICAL FEATURE; COMPULSION; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; GROUP A STREPTOCOCCAL INFECTION; HERITABILITY; HUMAN; HYPERACTIVITY; NEUROLOGIC DISEASE; OBSESSION; OBSESSIVE COMPULSIVE DISORDER; PATHOPHYSIOLOGY; PEDIATRIC AUTOIMMUNE NEUROLOGIC DISORDER ASSOCIATED WITH STREPTOCOCCUS; PHARYNGITIS; PRIORITY JOURNAL; STREPTOCOCCUS GROUP A; TIC; TONSILLECTOMY;

EID: 84934444329     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-79838-7_17     Document Type: Article

References (58)

1. Allen AJ, Leonard HL, Swedo SE. Case study: a new infection-triggered, autoimmune subtype of pediatric OCD and Tourette's syndrome. J Am Acad Child Adolesc Psychiatry 1995;34:307-311.
2. Cardona F. Orefici G. Group A streptococcal infections and tic disorders in an Italian pediatric population. J Pediatr 2001;138:71-75. (Pubitemid 32097144)
3. Chapman AH, Pilkey L, Gibbons MJ. A psychosomatic study of eight children with Sydenham's chorea. Pediatrics 1958;21:582-595.
4. Chappell P, Riddle M, Anderson G, Scahill L, Hardin M, Walker D et al. Enhanced stress responsively of Tourette syndrome patients undergoing lumbar puncture. Biol Psychiatry 1994;36(1):35-43. (Pubitemid 24210122)
5. Church AJ, Dale RC, Lees AJ, Giovannoni G, Robertson MM. Tourette's syndrome: a cross sectional study to examine the PANDAS hypothesis. J Neurol Neurosurg Psychiatry 2003;74:602-607.
6. Church AJ, Dale RC, Giovannoni G. Anti-basal ganglia antibodies: a possible diagnostic utility in idiopathic movement disorders? Arch Dis Child 2004;89:611-614.
7. Cunningham MW. Pathogenesis of group A streptococcal infections. Clin Microbiol Rev 2000;13(3):470-511. (Pubitemid 30452618)
8. Dale RC, Heyman I, Giovannoni G, Church AJ. Incidence of anti-brain antibodies in children with obsessive-compulsive disorder. Br J Psychiatry 2005;187:314-319. (Pubitemid 41442381)
9. Dale RC, Candler PM, Church AJ et al. Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autnoimmune CNS disease. J. Neuroimmunol 2006;172:187-197. (Pubitemid 43277505)
10. Garvey MA, Perlmutter SJ, Allen AJ, Hamburger S, Lougee L, Leonard HL et al. A piolot study of penicillin prophylaxis for neuropsychiatric exacerbatioins triggered by streptococcal infections. Biol Psychiatry 1999;45:1564-1571. (Pubitemid 29292832)
11. Giedd JN, Rapoport JL, Kruesi MJ, Parker C, Schapiro MB, Allen AJ et al. Sydenham's chorea: magnetic resonance imaging of the basal ganglia. Neurology 1995;45(12):2199-2202. (Pubitemid 27100248)
12. Giedd JN, Rapoport JL, Leonard HL, Richter D, Swedo SE. Case study: acute basal ganglia enlargement and obsessive-compulsive symptoms in an adolescent boy. J Am Acad Child Adolesc Psychiatry 1996;35(7):913-915. (Pubitemid 26230925)
13. Giuliano JD, Zimmerman A, Walkup JT, Singer HS. Prevalence of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection by history in a consecutive series of community referred children evaluated for tics. Ann Neurol. 1998;44(3):556.
14. Hallett JJ, Harling-Berg CJ, Knopf PM, Stopa EG, Kiessling LS. Anti-striatal antibodies in Tourette syndrome cause neuronal dysfunction. J Neuroimmunol 2000;111(1-2):195-202.
15. Husby G, van dRI, Zabriskie JB, Abdin ZH, Williams RC, Jr. Antibodies reacting with cytoplasm of subthalamic and caudate nuclei neurons in chorea and acute rheumatic fever. J Exp Med 1976;144(4):1094-1110.
16. Kaplan MH. Autoantibodies to heart and rheumatic fever: the induction of autoimmunity to heart by streptococcal antigen cross-reactive with heart. Ann N Y Acad Sci 1965;124(2):904-915.
17. Kaplan EL, Rothermel CD, Johnson DR. Antistreptolysin O and antideoxyribonuclease B titers: normal values for children ages 2 to 12 in the United States. Pediatrics 1998;101(1 Pt 1):86-88. (Pubitemid 28030329)
18. Kienzle GD, Breger RK, Chun RW, Zupanc ML, Sackett JF. Sydenham chorea: MR manifestations in two cases. AJNR Am J Neuroradiol 1991;12(1):73-76.
19. Kiessling et al. Speculations on Antineural Antibody-mediated Neuropsychiatric Disorders of Childhood. Pediatr 1994;93:323-326. (Pubitemid 24047173)
20. Kiessling LS, Marcotte AC, Culpepper L. Antineuronal antibodies in movement disorders. Pediatrics 1993;92(1):39-43. (Pubitemid 23188865)
21. Kiessling LS, Marcotte AC, Culpepper L. Antineuronal antibodies: tics and obsessivecompulsive symptoms. J Dev Behav Pediatr 1994;15(6):421-425.
22. Kirvan CA, Swedo SE, Snider LA, Cunningham MW. Antibody-mediated neuronal cell signaling in behavior and movement disorders. J Neuroimmunol 2006;179:173-179. (Pubitemid 44472532)
23. Klieger PS, Fett KA, Dimitsopulos T, Karlan R. Asymmetry of basal ganglia perfusion in Tourette's syndrome shown by technetium-99 m-HMPAO SPECT. J Nucl Med 1997;38:188-191. (Pubitemid 27061590)
24. Kurlan R. Tourette's syndrome and "PANDAS": will the relation bear out? Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection. Neurology 1998;50(6):1530-1534.
25. Kurlan R, Kaplan EL. The Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection (PANDAS) Etiology for Tics and Obsessive-Compulsive Symptoms: Hypothesis or Entity? Practical Considerations for the Clinician. Pediatr 2004;113:883-886. (Pubitemid 38437396)
26. Lin H, Yeh C-B, Peterson BS, Scahill L, Grantz H, Findley DB et al. Assessment of symptom exacerbations in a longitudinal study of children with Tourette syndrome or obsessivecompulsive disorder. J Am Acad Child Adolesc Psychiatry 2002;41.
27. Lougee L, Perlmutter SJ, Nicolson R, Garvey MA, Swedo SE. Psychiatric disorders in first-degree relatives of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). J Am Acad Child Adolesc Psychiatry 2000;39(9):1120-1126.
28. Luo F, Leckman JF, Katsovich L et al. Prospective longitudinal study of children with tic disorders and/or obsessive-compulsive disorder: relationship of symptom exacerbations to newly acquired streptococcal infections. Pediatrics 2004;113(6):e578-e585.
29. Mell LK, Davis RL, Ownes D. Association between streptococcal infection and obsessive-compulsive disorder, Tourette's syndrome, and tic disorder. Pediatrics 2005;116(1):56-60.
30. Morshed SA, Parveen S, Leckman JF, Mercadante MT et al. Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette's syndrome, Sydenham's chorea, and autoimmune disorders. Biol Psychiatry 2001;50:566-577. (Pubitemid 33022641)
31. Murphy TK, Goodman WK, Fudge MW, Williams RC, Jr, Ayoub EM, Dalal M et al. B lymphocyte antigen D8/17: a peripheral marker for childhood-onset obsessivecompulsive disorder and Tourette's syndrome? Am J Psychiatry 1997;154(3):402-407. (Pubitemid 27098292)
32. Murphy TK, Goodman WK, Ayoub EM, Voeller KK. On defining Sydenham's chorea: where do we draw the line? Biol Psychiatry 2000;47(10):851-857. (Pubitemid 30243172)
33. Murphy ML, Pichichero ME. Prospective identification and treatment of children with pediatric autoimmune neuropsychiatric disorder associated with group A streptococcal infection (PANDAS). Arch Pediatr Adolesc Med 2002;156:356-361. (Pubitemid 34274183)
34. Orvidas LJ, Slattery MJ. Pediatric autoimmune neuropsychiatric disorders and streptococcal infections: role of otolaryngologist. Laryngoscope 2001;111(9):1515-1519. (Pubitemid 32843847)
35. O'Sullivan RL, Rauch SL, Breiter HC et al. Reduced basal ganglia volumes in trichotillomania measured via morphometric magnetic resonance imaging. Biol Psychiatry 1997;42:39-45. (Pubitemid 27293534)
36. Pauls DL. Update on the genetics of Tourette syndrome. Adv Neurol 2001;85:281-293.
37. Pauls DL, Raymond CL, Stevenson JM, Leckman JF. A family study of Gilles de la Tourette syndrome. Am J Hum Genet 1991;48(1):154-163. (Pubitemid 21903038)
38. Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL et al. Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood. Lancet 1999;354(9185):1153-1158. (Pubitemid 29460444)
39. Perrin EM, Murphy ML, Casey JR, Pichichero ME, Runyan DK, Miller WC, Snider LA, Swedo SE. Does group A b-hemolytic streptococcal infection increase risk for behavioral and neuropsychiatric symptoms in children? Arch Pediatr Adolesc Med 2004;158:848-856. (Pubitemid 39181085)
40. Peterson BS. Neuroimaging in child and adolescent neuropsychatric disorders. J Am Acad Child Adolesc Psychiatry 1995;34:1560-1576.
41. Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H et al. Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders. Arch Gen Psychiatry 2000;57(4):364-372. (Pubitemid 30202327)
42. Rasmussen SA, Tsuang MT. Clinical characteristics and family history in DSM-III obsessivecompulsive disorder. Am J Psychiatry 1986;143(3):317-322. (Pubitemid 16034090)
43. Singer HS, Giuliano JD, Hansen BH, Hallett JJ, Laurino JP, Benson M et al. Antibodies against human putamen in children with Tourette syndrome. Neurology 1998;50(6):1618-1624. (Pubitemid 28283226)
44. Singer HS. PANDAS and immunomodulatory therapy. Lancet 1999;354(9185):1137-1138. (Pubitemid 29460437)
45. Snider LA, Seligman LD, Ketchen BR et al. Tics and problem behaviors in schoolchildren: prevalence, characterization, and associations. Pediatrics 2002;110:331-336. (Pubitemid 34833018)
46. Snider LA, Lougee L, Slattery M, Grant P, Swedo SE. Antibiotic prophylaxis with azithromycin or penicillin for childhood-onset neuropsychiatric disorders. Biol Psychiatry 2005;57:788-792. (Pubitemid 40487923)
47. Stollerman GH. Rheumatic fever and streptococcal infection: unraveling the mysteries of a dread disease. Boston: 1997.
48. Swedo SE. Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections: Clinical Description of the First 50 Cases. Am J Psychiatry 1998;155:264-271. (Pubitemid 28074291)
49. Swedo SE. The Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection (PANDAS) Subgroup: Separating Fact from Fiction. Pediatr 2004;113:907-911. (Pubitemid 38437398)
50. Swedo SE, Rapoport JL, Cheslow DL, Leonard HL, Ayoub EM, Hosier DM et al. High prevalence of obsessive-compulsive symptoms in patients with Sydenham's chorea. Am J Psychiatry 1989;146(2):246-249. (Pubitemid 19059576)
51. Swedo SE, Rapoport JL, Leonard H, Lenane M, Cheslow D. Obsessive-compulsive disorder in children and adolescents: clinical phenomenology of 70 consecutive cases. Arch Gen Psychiatry 1989;46:335-341. (Pubitemid 19111487)
52. Swedo et al. Syndenharn's Chorea: a Model for Childhood Autoimmune Neuropsychiatric Disorders. JAMA 1994;272:1788-1791. (Pubitemid 24372008)
53. Swedo SE, Leonard HL, Kiessling LS. Speculations on antineuronal antibody-mediated neuropsychiatric disorders of childhood. Pediatrics 1994;93:323-326. (Pubitemid 24047173)
54. Swedo SE, Leonard HL, Mittleman BB et al. Identification of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections by a marker associated with rheumatic fever. Am J Psychiatry 1997;154:110-112. (Pubitemid 27020203)
55. Swedo SE, Leonard HL, Garvey M, Mittleman B, Allen AJ, Perlmutter S et al. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases. Am J Psychiatry 1998;155(2):264-271. (Pubitemid 28074291)
56. Traill Z, Pike M, Byrne J. Sydenham's chorea: a case showing reversible striatal abnormalities on CT and MRI. Dev Med Child Neurol 1995;37(3):270-273.
57. Trifiletti RR. TS83: Candidate target brain autoantigen in Tourette Syndrome and OCD. Ann. Neurol. 1998;44(3):561.
58. Trifiletti RR, Altemus M, Packard AM, Bandele AN, Zabriskie JB. Changes in Antineuronal Antibodies following conventional and immunosuppressive therapy for Tourette's syndrome and obsessive-compulsive disorder. Ann. Neurol. 1998;44(3):561.