Mitochondrial dysfunction in aging rat brain following transient global ischemia

Advances in Experimental Medicine and Biology

Volumn 614, Issue , 2008, Pages 379-386

  Xu, Kui ^a   Puchowicz, Michelle A ^a   Sun, Xiaoyan ^a   Lamanna, Joseph C ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ADENOSINE DIPHOSPHATE; MITOCHONDRIAL PROTEIN; N TERT BUTYL ALPHA PHENYLNITRONE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN STEM; CONFERENCE PAPER; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HEART ARREST; LIPID PEROXIDATION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; RESUSCITATION; TRANSIENT ISCHEMIC ATTACK;

RATTUS;

EID: 84934442093     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-74911-2_42     Document Type: Conference Paper

References (8)

1. J. Lehotsky, R. Murin, A. Strapkova, A. Urikova, Z. Tatarkova, and P. Kaplan, Time course of ischemia/reperfusion-induced oxidative modification of neural proteins in rat forebrain, Gen. Physiol. Biophys. 23(4), 401-415 (2004).
2. K. Xu, X. Sun, M. A. Puchowicz, and J. C. LaManna, Increased sensitivity to transient global ischemia in aging rat brain, Adv. Exp. Med. Biol. 599, 199-206 (2007).
3. J. C. LaManna, N. L. Neubauer, and J. C. Chavez, In: Matuation Phenomenon in Cerebral Ischemia IV, edited by Bazen NG, Ito U, Maecheselli VL, Kuroiwa T, and Klatzo I (Springer-Verlag, Berlin Heidelberg, 2001), pp. 223-227.
4. J. W. Phillis and C. Clough-Helfman, Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-alpha-phenylnitrone (PBN), Neurosci. Lett. 116(3), 315-319 (1990).
5. D. T. Lucas and L. I. Szweda, Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction, Proc. Natl. Acad. Sci. U. S. A. 95(2), 510-514 (1998).
6. M. F. Anderson and N. R. Sims, Mitochondrial respiratory function and cell death in focal cerebral ischemia, J. Neurochem. 73(3), 1189-1199 (1999).
7. K. Xu, M. A. Puchowicz, W. D. Lust, and J. C. Lamanna, Adenosine treatment delays postischemic hippocampal CA1 loss after cardiac arrest and resuscitation in rats, Brain Res. 1071(1), 208-217 (2006).
8. J. Kerner, P. J. Turkaly, P. E. Minkler, and C. L. Hoppel, Aging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content, Am. J. Physiol Endocrinol. Metab. 281(5), E1054-E1062 (2001).