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Volumn 588, Issue , 2006, Pages 75-88

Neural consequences of sleep disordered breathing: The role of intermittent hypoxia

Author keywords

Cognitive; Memory; Periodic breathing; Sleep apnea

Indexed keywords


EID: 84934436275     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-34817-9_8     Document Type: Conference Paper
Times cited : (59)

References (67)
  • 1
    • 0034948540 scopus 로고    scopus 로고
    • Relation of measures of sleep-disordered breathing to neuropsychological functioning
    • Adams N, Strauss M, Schluchter M, and Redline S. Relation of measures of sleep-disordered breathing to neuropsychological functioning. Am J Respir Crit Care Med 163: 1626-1631, 2001.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 1626-1631
    • Adams, N.1    Strauss, M.2    Schluchter, M.3    Redline, S.4
  • 2
    • 0034921669 scopus 로고    scopus 로고
    • Neuropsychological effects of one-week continuous positive airway pressure treatment in patients with obstructive sleep apnea: A placebo-controlled study
    • Bardwell WA, Ancoli-Israel S, Berry CC, and Dimsdale JE. Neuropsychological effects of one-week continuous positive airway pressure treatment in patients with obstructive sleep apnea: a placebo-controlled study. Psychosom Med 63: 579-584, 2001.
    • (2001) Psychosom Med , vol.63 , pp. 579-584
    • Bardwell, W.A.1    Ancoli-Israel, S.2    Berry, C.C.3    Dimsdale, J.E.4
  • 5
    • 0027193461 scopus 로고
    • Persistent neuropsychological deficits and vigilance impairment in sleep apnea syndrome after treatment with continuous positive airways pressure (CPAP)
    • Bedard MA, Montplaisir J, Malo J, Richer F, and Rouleau I. Persistent neuropsychological deficits and vigilance impairment in sleep apnea syndrome after treatment with continuous positive airways pressure (CPAP). J Clin Exp Neuropsychol 15: 330-341, 1993.
    • (1993) J Clin Exp Neuropsychol , vol.15 , pp. 330-341
    • Bedard, M.A.1    Montplaisir, J.2    Malo, J.3    Richer, F.4    Rouleau, I.5
  • 8
  • 9
    • 0026556196 scopus 로고
    • Factors impairing daytime performance in patients with sleep apnea/hypopnea syndrome
    • Cheshire K, Engleman H, Deary I, Shapiro C, and Douglas NJ. Factors impairing daytime performance in patients with sleep apnea/hypopnea syndrome. Arch Intern Med 152: 538-541, 1992.
    • (1992) Arch Intern Med , vol.152 , pp. 538-541
    • Cheshire, K.1    Engleman, H.2    Deary, I.3    Shapiro, C.4    Douglas, N.J.5
  • 10
    • 0029680369 scopus 로고    scopus 로고
    • The hippocampus: A "working memory" structure? The effect of hippocampal sclerosis on working memory
    • Cowey CM and Green S. The hippocampus: a "working memory" structure? The effect of hippocampal sclerosis on working memory. Memory 4: 19-30, 1996.
    • (1996) Memory , vol.4 , pp. 19-30
    • Cowey, C.M.1    Green, S.2
  • 11
    • 0035884863 scopus 로고    scopus 로고
    • Case control study of cerebrovascular damage defined by magnetic resonance imaging in patients with OSA and normal matched control subjects
    • Davies CW, Crosby JH, Mullins RL, Traill ZC, Anslow P, Davies RJ, and Stradling JR. Case control study of cerebrovascular damage defined by magnetic resonance imaging in patients with OSA and normal matched control subjects. Sleep 24: 715-720, 2001.
    • (2001) Sleep , vol.24 , pp. 715-720
    • Davies, C.W.1    Crosby, J.H.2    Mullins, R.L.3    Traill, Z.C.4    Anslow, P.5    Davies, R.J.6    Stradling, J.R.7
  • 12
    • 0037459793 scopus 로고    scopus 로고
    • Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signaling
    • Decker MJ, Hue GE, Caudle WM, Miller GW, Keating GL, and Rye DB. Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signaling. Neuroscience 117: 417-425, 2003.
    • (2003) Neuroscience , vol.117 , pp. 417-425
    • Decker, M.J.1    Hue, G.E.2    Caudle, W.M.3    Miller, G.W.4    Keating, G.L.5    Rye, D.B.6
  • 14
    • 0034307762 scopus 로고    scopus 로고
    • Common regions of the human frontal lobe recruited by diverse cognitive demands
    • Duncan J and Owen AM. Common regions of the human frontal lobe recruited by diverse cognitive demands. Trends Neurosci 23: 475-483, 2000.
    • (2000) Trends Neurosci , vol.23 , pp. 475-483
    • Duncan, J.1    Owen, A.M.2
  • 15
    • 0037251057 scopus 로고    scopus 로고
    • Executive functions and their disorders
    • Elliott R. Executive functions and their disorders. Br Med Bull 65: 49-59, 2003.
    • (2003) Br Med Bull , vol.65 , pp. 49-59
    • Elliott, R.1
  • 16
    • 0027520665 scopus 로고
    • Daytime sleepiness, cognitive performance and mood after continuous positive airway pressure for the sleep apnoea/hypopnoea syndrome
    • Engleman HM, Cheshire KE, Deary IJ, and Douglas NJ. Daytime sleepiness, cognitive performance and mood after continuous positive airway pressure for the sleep apnoea/hypopnoea syndrome. Thorax 48: 911-914, 1993.
    • (1993) Thorax , vol.48 , pp. 911-914
    • Engleman, H.M.1    Cheshire, K.E.2    Deary, I.J.3    Douglas, N.J.4
  • 17
    • 0027958394 scopus 로고
    • Effect of continuous positive airway pressure treatment on daytime function in sleep apnoea/hypopnoea syndrome
    • Engleman HM, Martin SE, Deary IJ, and Douglas NJ. Effect of continuous positive airway pressure treatment on daytime function in sleep apnoea/hypopnoea syndrome. Lancet 343: 572-575, 1994.
    • (1994) Lancet , vol.343 , pp. 572-575
    • Engleman, H.M.1    Martin, S.E.2    Deary, I.J.3    Douglas, N.J.4
  • 18
    • 0031017488 scopus 로고    scopus 로고
    • Effect of CPAP therapy on daytime function in patients with mild sleep apnoea/hypopnoea syndrome
    • Engleman HM, Martin SE, Deary IJ, and Douglas NJ. Effect of CPAP therapy on daytime function in patients with mild sleep apnoea/hypopnoea syndrome. Thorax 52: 114-119, 1997.
    • (1997) Thorax , vol.52 , pp. 114-119
    • Engleman, H.M.1    Martin, S.E.2    Deary, I.J.3    Douglas, N.J.4
  • 19
    • 0031839451 scopus 로고    scopus 로고
    • Randomised placebo controlled trial of daytime function after continuous positive airway pressure (CPAP) therapy for the sleep apnoea/hypopnoea syndrome
    • Engleman HM, Martin SE, Kingshott RN, Mackay TW, Deary IJ, and Douglas NJ. Randomised placebo controlled trial of daytime function after continuous positive airway pressure (CPAP) therapy for the sleep apnoea/hypopnoea syndrome. Thorax 53: 341-345, 1998.
    • (1998) Thorax , vol.53 , pp. 341-345
    • Engleman, H.M.1    Martin, S.E.2    Kingshott, R.N.3    Mackay, T.W.4    Deary, I.J.5    Douglas, N.J.6
  • 20
    • 0038210192 scopus 로고    scopus 로고
    • Cognitive dysfunction in patients with obstructive sleep apnea (OSA): Partial reversibility after continuous positive airway pressure (CPAP)
    • Ferini-Strambi L, Baietto C, Di Gioia MR, Castaldi P, Castronovo C, Zucconi M, and Cappa SF. Cognitive dysfunction in patients with obstructive sleep apnea (OSA): partial reversibility after continuous positive airway pressure (CPAP). Brain Res Bull 61: 87-92, 2003.
    • (2003) Brain Res Bull , vol.61 , pp. 87-92
    • Ferini-Strambi, L.1    Baietto, C.2    Di Gioia, M.R.3    Castaldi, P.4    Castronovo, C.5    Zucconi, M.6    Cappa, S.F.7
  • 21
    • 0031155931 scopus 로고    scopus 로고
    • Frontal lobe-related cogintive functions in patients with sleep apnea syndrome before and after treatment
    • Feuerstein C, Naegele B, Pepin JL, and Levy P. Frontal lobe-related cogintive functions in patients with sleep apnea syndrome before and after treatment. Acta Neurol Belg 97: 96-107, 1997.
    • (1997) Acta Neurol Belg , vol.97 , pp. 96-107
    • Feuerstein, C.1    Naegele, B.2    Pepin, J.L.3    Levy, P.4
  • 22
    • 1442305222 scopus 로고    scopus 로고
    • Effects of hypoxia on the brain: Neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apnea
    • Gale SD and Hopkins RO. Effects of hypoxia on the brain: neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apnea. J Int Neuropsychol Soc 10: 60-71, 2004.
    • (2004) J Int Neuropsychol Soc , vol.10 , pp. 60-71
    • Gale, S.D.1    Hopkins, R.O.2
  • 24
    • 85047686160 scopus 로고    scopus 로고
    • Source memory in older adults: An encoding or retrieval problem?
    • Glisky EL, Rubin SR, and Davidson PS. Source memory in older adults: an encoding or retrieval problem? J Exp Psychol Learn Mem Cogn 27: 1131-1146, 2001.
    • (2001) J Exp Psychol Learn Mem Cogn , vol.27 , pp. 1131-1146
    • Glisky, E.L.1    Rubin, S.R.2    Davidson, P.S.3
  • 25
    • 10744223115 scopus 로고    scopus 로고
    • Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region: Water maze performance correlates
    • Goldbart A, Row BW, Kheirandish L, Schurr A, Gozal E, Guo SZ, Payne RS, Cheng Z, Brittian KR, and Gozal D. Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region: water maze performance correlates. Neuroscience 122: 585-590, 2003.
    • (2003) Neuroscience , vol.122 , pp. 585-590
    • Goldbart, A.1    Row, B.W.2    Kheirandish, L.3    Schurr, A.4    Gozal, E.5    Guo, S.Z.6    Payne, R.S.7    Cheng, Z.8    Brittian, K.R.9    Gozal, D.10
  • 27
    • 0035313599 scopus 로고    scopus 로고
    • Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat
    • Gozal D, Daniel JM, and Dohanich GP. Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat. J Neurosci 21: 2442-2450, 2001.
    • (2001) J Neurosci , vol.21 , pp. 2442-2450
    • Gozal, D.1    Daniel, J.M.2    Dohanich, G.P.3
  • 28
    • 0141543816 scopus 로고    scopus 로고
    • Increased susceptibility to intermittent hypoxia in aging rats: Changes in proteasomal activity, neuronal apoptosis and spatial function
    • Gozal D, Row BW, Kheirandish L, Liu R, Guo SZ, Qiang F, and Brittian KR. Increased susceptibility to intermittent hypoxia in aging rats: changes in proteasomal activity, neuronal apoptosis and spatial function. J Neurochem 86: 1545-1552, 2003.
    • (2003) J Neurochem , vol.86 , pp. 1545-1552
    • Gozal, D.1    Row, B.W.2    Kheirandish, L.3    Liu, R.4    Guo, S.Z.5    Qiang, F.6    Brittian, K.R.7
  • 29
    • 0023498220 scopus 로고
    • Neuropsychological dysfunction in sleep apnea
    • Greenberg GD, Watson RK, and Deptula D. Neuropsychological dysfunction in sleep apnea. Sleep 10: 254-262, 1987.
    • (1987) Sleep , vol.10 , pp. 254-262
    • Greenberg, G.D.1    Watson, R.K.2    Deptula, D.3
  • 30
    • 0034870755 scopus 로고    scopus 로고
    • Decreased neuronal excitability in hippocampal neurons of mice exposed to cyclic hypoxia
    • Gu XQ and Haddad GG. Decreased neuronal excitability in hippocampal neurons of mice exposed to cyclic hypoxia. J Appl Physiol 91: 1245-1250, 2001.
    • (2001) J Appl Physiol , vol.91 , pp. 1245-1250
    • Gu, X.Q.1    Haddad, G.G.2
  • 31
    • 0037834504 scopus 로고    scopus 로고
    • Sleep deprivation reduces proliferation of cells in the dentate gyms of the hippocampus in rats
    • Guzman-Marin R, Suntsova N, Stewart DR, Gong H, Szymusiak R, and McGinty D. Sleep deprivation reduces proliferation of cells in the dentate gyms of the hippocampus in rats. J Physiol 549: 563-571, 2003.
    • (2003) J Physiol , vol.549 , pp. 563-571
    • Guzman-Marin, R.1    Suntsova, N.2    Stewart, D.R.3    Gong, H.4    Szymusiak, R.5    McGinty, D.6
  • 32
    • 0027454115 scopus 로고
    • Mechanisms of anoxia-induced depolarization in brainstem neurons: In vitro current and voltage clamp studies in the adult rat
    • Haddad GG and Jiang C. Mechanisms of anoxia-induced depolarization in brainstem neurons: in vitro current and voltage clamp studies in the adult rat. Brain Res 625: 261-268, 1993.
    • (1993) Brain Res , vol.625 , pp. 261-268
    • Haddad, G.G.1    Jiang, C.2
  • 34
    • 0021883228 scopus 로고
    • Severe obstructive sleep apnea - II: Associated psychopathology and psychosocial consequences
    • Kales A, Caldwell AB, Cadieux RJ, Vela-Bueno A, Ruch LG, and Mayes SD. Severe obstructive sleep apnea - II: Associated psychopathology and psychosocial consequences. J Chronic Dis 38: 427-434, 1985.
    • (1985) J Chronic Dis , vol.38 , pp. 427-434
    • Kales, A.1    Caldwell, A.B.2    Cadieux, R.J.3    Vela-Bueno, A.4    Ruch, L.G.5    Mayes, S.D.6
  • 42
    • 0345578680 scopus 로고    scopus 로고
    • Semantic memory and the human hippocampus
    • Manns JR, Hopkins RO, and Squire LR. Semantic memory and the human hippocampus. Neuron 38: 127-133, 2003.
    • (2003) Neuron , vol.38 , pp. 127-133
    • Manns, J.R.1    Hopkins, R.O.2    Squire, L.R.3
  • 44
    • 13444258030 scopus 로고    scopus 로고
    • Most obstructive sleep apnoea patients exhibit vigilance and attention deficits on an extended battery of tests
    • Mazza S, Pepin JL, Naegele B, Plante J, Deschaux C, and Levy P. Most obstructive sleep apnoea patients exhibit vigilance and attention deficits on an extended battery of tests. Eur Respir J 25: 75-80, 2005.
    • (2005) Eur Respir J , vol.25 , pp. 75-80
    • Mazza, S.1    Pepin, J.L.2    Naegele, B.3    Plante, J.4    Deschaux, C.5    Levy, P.6
  • 45
    • 0142244116 scopus 로고    scopus 로고
    • Sleep deprivation causes behavioral, synaptic, and membrane excitability alterations in hippocampal neurons
    • McDermott CM, LaHoste GJ, Chen C, Musto A, Bazan NG, and Magee JC. Sleep deprivation causes behavioral, synaptic, and membrane excitability alterations in hippocampal neurons. J Neurosci 23: 9687-9695, 2003.
    • (2003) J Neurosci , vol.23 , pp. 9687-9695
    • McDermott, C.M.1    LaHoste, G.J.2    Chen, C.3    Musto, A.4    Bazan, N.G.5    Magee, J.C.6
  • 46
    • 0027050652 scopus 로고
    • Neurobehavioral manifestations in obstructive sleep apnea syndrome before and after treatment with continuous positive airway pressure
    • Montplaisir J, Bedard MA, Richer F, and Rouleau I. Neurobehavioral manifestations in obstructive sleep apnea syndrome before and after treatment with continuous positive airway pressure. Sleep 15: S17-19, 1992.
    • (1992) Sleep , vol.15
    • Montplaisir, J.1    Bedard, M.A.2    Richer, F.3    Rouleau, I.4
  • 47
    • 0141669301 scopus 로고    scopus 로고
    • Morrell MJ, McRobbie DW, Quest RA, Cummin AR, Ghiassi R, and Corfield DR. Changes in brain morphology associated with obstructive sleep apnea. Sleep Med 4: 451-454, 2003.
    • Morrell MJ, McRobbie DW, Quest RA, Cummin AR, Ghiassi R, and Corfield DR. Changes in brain morphology associated with obstructive sleep apnea. Sleep Med 4: 451-454, 2003.
  • 49
    • 0017893403 scopus 로고
    • Hippocampal place units in the freely moving rat: Why they fire where they fire
    • O'Keefe J and Conway DH. Hippocampal place units in the freely moving rat: why they fire where they fire. Exp Brain Res 31: 573-590, 1978.
    • (1978) Exp Brain Res , vol.31 , pp. 573-590
    • O'Keefe, J.1    Conway, D.H.2
  • 50
    • 12744258044 scopus 로고    scopus 로고
    • Intermittent hypoxia damages cerebellar cortex and deep nuclei
    • Pae EK, Chien P, and Harper RM. Intermittent hypoxia damages cerebellar cortex and deep nuclei. Neurosci Lett 375: 123-128, 2005.
    • (2005) Neurosci Lett , vol.375 , pp. 123-128
    • Pae, E.K.1    Chien, P.2    Harper, R.M.3
  • 51
    • 7944230044 scopus 로고    scopus 로고
    • Effect of intermittent hypoxia on long-term potentiation in rat hippocampal slices
    • Payne RS, Goldbart A, Gozal D, and Schurr A. Effect of intermittent hypoxia on long-term potentiation in rat hippocampal slices. Brain Res 1029: 195-199, 2004.
    • (2004) Brain Res , vol.1029 , pp. 195-199
    • Payne, R.S.1    Goldbart, A.2    Gozal, D.3    Schurr, A.4
  • 52
    • 2542432073 scopus 로고    scopus 로고
    • Oxidative stress in the systemic and cellular responses to intermittent hypoxia
    • Prabhakar NR, and Kumar, GK. Oxidative stress in the systemic and cellular responses to intermittent hypoxia. Biol Chem 385: 217-221, 2004.
    • (2004) Biol Chem , vol.385 , pp. 217-221
    • Prabhakar, N.R.1    Kumar, G.K.2
  • 55
    • 85047684454 scopus 로고    scopus 로고
    • Impaired spatial learning and hyperactivity in developing rats exposed to intermittent hypoxia
    • Row BW, Kheirandish L, Neville JJ, and Gozal D. Impaired spatial learning and hyperactivity in developing rats exposed to intermittent hypoxia. Pediatr Res 52: 449-453, 2002.
    • (2002) Pediatr Res , vol.52 , pp. 449-453
    • Row, B.W.1    Kheirandish, L.2    Neville, J.J.3    Gozal, D.4
  • 56
    • 0038132134 scopus 로고    scopus 로고
    • Intermittent hypoxia is associated with oxidative stress and spatial learning deficits in the rat
    • Row BW, Liu R, Xu W, Kheirandish L, and Gozal D. Intermittent hypoxia is associated with oxidative stress and spatial learning deficits in the rat. Am J Respir Crit Care Med 167: 1548-1553, 2003.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1548-1553
    • Row, B.W.1    Liu, R.2    Xu, W.3    Kheirandish, L.4    Gozal, D.5
  • 57
    • 3042613475 scopus 로고    scopus 로고
    • Sleep deprivation impairs hippocampus-mediated contextual learning but not amygdala-mediated cued learning in rats
    • Ruskin DN, Liu C, Dunn KE, Bazan NG, and LaHoste GJ. Sleep deprivation impairs hippocampus-mediated contextual learning but not amygdala-mediated cued learning in rats. Eur J Neurosci 19: 3121-3124, 2004.
    • (2004) Eur J Neurosci , vol.19 , pp. 3121-3124
    • Ruskin, D.N.1    Liu, C.2    Dunn, K.E.3    Bazan, N.G.4    LaHoste, G.J.5
  • 59
    • 0026748602 scopus 로고
    • Daytime sleepiness after long-term continuous positive airway pressure (CPAP) treatment in obstructive sleep apnea syndrome
    • Sforza E and Krieger J. Daytime sleepiness after long-term continuous positive airway pressure (CPAP) treatment in obstructive sleep apnea syndrome. J Neurol Sci 110: 21-26, 1992.
    • (1992) J Neurol Sci , vol.110 , pp. 21-26
    • Sforza, E.1    Krieger, J.2
  • 60
    • 0037621857 scopus 로고    scopus 로고
    • Distinct prefrontal cortex activity associated with item memory and source memory for visual shapes
    • Slotnick SD, Moo LR, Segal JB, and Hart J, Jr. Distinct prefrontal cortex activity associated with item memory and source memory for visual shapes. Brain Res Cogn Brain Res 17: 75-82, 2003.
    • (2003) Brain Res Cogn Brain Res , vol.17 , pp. 75-82
    • Slotnick, S.D.1    Moo, L.R.2    Segal, J.B.3    Hart Jr., J.4
  • 61
    • 0025817129 scopus 로고
    • Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men
    • Stradling JR and Crosby JH. Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men. Thorax 46: 85-90, 1991.
    • (1991) Thorax , vol.46 , pp. 85-90
    • Stradling, J.R.1    Crosby, J.H.2
  • 62
    • 0020287572 scopus 로고
    • Spatial mapping: Definitive disruption by hippocampal or medial frontal cortical damage in the rat
    • Sutherland RJ, Kolb B, and Whishaw IQ. Spatial mapping: definitive disruption by hippocampal or medial frontal cortical damage in the rat. Neurosci Lett 31: 271-276, 1982.
    • (1982) Neurosci Lett , vol.31 , pp. 271-276
    • Sutherland, R.J.1    Kolb, B.2    Whishaw, I.Q.3
  • 63
    • 19444375864 scopus 로고    scopus 로고
    • Functional imaging of working memory in obstructive sleep-disordered breathing
    • Thomas RJ, Rosen BR, Stern CE, Weiss JW, and Kwong KK. Functional imaging of working memory in obstructive sleep-disordered breathing. J Appl Physiol, 98: 2226-2234, 2005.
    • (2005) J Appl Physiol , vol.98 , pp. 2226-2234
    • Thomas, R.J.1    Rosen, B.R.2    Stern, C.E.3    Weiss, J.W.4    Kwong, K.K.5
  • 64
    • 3242744596 scopus 로고    scopus 로고
    • Long-term intermittent hypoxia in mice: Protracted hypersomnolence with oxidative injury to sleep-wake brain regions
    • Veasey SC, Davis CW, Fenik P, Zhan G, Hsu YJ, Pratico D, and Gow A. Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions. Sleep 27: 194-201, 2004.
    • (2004) Sleep , vol.27 , pp. 194-201
    • Veasey, S.C.1    Davis, C.W.2    Fenik, P.3    Zhan, G.4    Hsu, Y.J.5    Pratico, D.6    Gow, A.7
  • 66
    • 0034085503 scopus 로고    scopus 로고
    • The efficacy of nasal continuous positive airway pressure in the treatment of obstructive sleep apnea syndrome is not proven
    • Wright J and Sheldon T. The efficacy of nasal continuous positive airway pressure in the treatment of obstructive sleep apnea syndrome is not proven. Am J Respir Crit Care Med 161: 1776-1778, 2000.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1776-1778
    • Wright, J.1    Sheldon, T.2
  • 67
    • 0027462562 scopus 로고
    • The occurrence of sleep-disordered breathing among middle-aged adults
    • Young T, Palta M, Dempsey J, Skatrud J, Weber S, and Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328: 1230-1235, 1993.
    • (1993) N Engl J Med , vol.328 , pp. 1230-1235
    • Young, T.1    Palta, M.2    Dempsey, J.3    Skatrud, J.4    Weber, S.5    Badr, S.6


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