Effect of oxygenation on stem-cell therapy for myocardial infarction

Advances in Experimental Medicine and Biology

Volumn 701, Issue , 2011, Pages 175-181

  Khan, Mahmood ^a   Meduru, Sarath ^a   Pandian, Ramasamy P ^a   Rivera, Brian K ^a   Kuppusamy, Periannan ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA1 INTEGRIN; VASCULOTROPIN;

ACUTE HEART INFARCTION; ADULT STEM CELL; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; ECHOCARDIOGRAPHY; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPERBARIC OXYGEN; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; THERAPY EFFECT; UPREGULATION;

EID: 84934435365     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-7756-4_24     Document Type: Conference Paper

References (9)

1. Guarita-Souza LC, Carvalho KA, Rebelatto C et al (2006) Cell transplantation: Differential effects of myoblasts and mesenchymal stem cells. Int J Cardiol 111:423-429. (Pubitemid 44205295)
2. Kuramochi Y, Fukazawa R,MigitaMet al (2003) Cardiomyocyte regeneration from circulating bone marrow cells in mice. Pediatr Res 54:319-325. (Pubitemid 37013192)
3. Khan M, Kutala VK, Vikram DS et al (2007) Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function. Am J Physiol Heart Circ Physiol 293:H2129-2139. (Pubitemid 47605854)
4. Sterling DL, Thornton JD, Swafford A et al (1993) Hyperbaric oxygen limits infarct size in ischemic rabbit myocardium in vivo. Circulation 88:1931-1936. (Pubitemid 23296941)
5. Pandian RP, Parinandi NL, Ilangovan G et al (2003) Novel particulate spin probe for targeted determination of oxygen in cells and tissues. Free Radic Biol Med 35:1138-1148. (Pubitemid 37315706)
6. Khan M, Meduru S, Mohan IK et al (2009) Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart. J Mol Cell Cardiol 47:275-287.
7. Wisel S, Khan M, Kuppusamy ML et al (2009) Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression. J Pharmacol Exp Ther 329:543-550.
8. Chacko SM, Khan M, Kuppusamy ML et al (2009) Myocardial oxygenation and functional recovery in infarct rat hearts transplanted with mesenchymal stem cells. Am J Physiol Heart Circ Physiol 296:H1263-1273.
9. Khan M, Kutala VK, Wisel S et al (2008) Measurement of oxygenation at the site of stem cell therapy in a murine model of myocardial infarction. Adv Exp Med Biol 614:45-52.