Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models

Methods in Molecular Biology

Volumn 1114, Issue , 2014, Pages 371-383

  Fine, Eli J ^a   Cradick, Thomas J ^a   Bao, Gang ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Bioinformatics; Gene targeting; Gene therapy; Off target effects; Off target sites; TALEN; Transcription activator like effector nuclease; ZFN; Zinc finger nuclease

Indexed keywords

RESTRICTION ENDONUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

ARTICLE; GENE AMPLIFICATION; GENE TARGETING; HIGH THROUGHPUT SEQUENCING; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE;

ANIMALS; COMPUTATIONAL BIOLOGY; DNA CLEAVAGE; ENDONUCLEASES; SUBSTRATE SPECIFICITY; ZINC FINGERS;

EID: 84934434741     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-761-7_24     Document Type: Article

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