Development of a visible spectrophotometric method for the analysis of ganciclovir in bulk sample and dosage form

Tropical Journal of Pharmaceutical Research

Volumn 14, Issue 6, 2015, Pages 1095-1101

  Thomas, Olusegun E ^a   Adegoke, Olajire A ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Absorption spectrophotometry; Diazo coupling reaction; Ganciclovir; P dimethylaminobenzaldehyde

Indexed keywords

EID: 84934344087     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v14i6.23     Document Type: Article

References (22)

1. Perrottet N, Decosterd LA, Meylan P, Pascual M, Biollaz J, Buclin T. Valganciclovir in adult solid organ transplant recipients: pharmacokinetic and pharmacodynamic characteristics and clinical interpretation of plasma concentration measurements. Clin Pharmacokinet. 2009; 48: 399-418
2. Asberg A, Rollag H, Hartmann A. Valganciclovir for the prevention and treatment of CMV in solid organ transplant recipients. Expert Opin Pharmacother. 2010; 11: 1159-1166
3. Matthews T, Boehme R. Antiviral activity and mechanism of action of ganciclovir. Rev Infect Dis. 1988; 10: S490-S494
4. Martindale The Complete Drug Reference ed 36. London, Pharmaceutical Press, 2009
5. Padulles A, Colom H, Armendariz Y, Cerezo G, Caldes A, Pou L, Torras J, Grinyo JM, Lloberas N. Determination of ganciclovir in human plasma by ultra performance liquid chromatography–UV detection. Clin Biochem. 2012; 45: 309-314
6. Merodio M, Campanero MA, Mirshahi T, Mirshahi M, Irache JM. Development of a sensitive method for the determination of ganciclovir by reversed-phase high-performance liquid chromatography. J Chromatogr. 2000; 870: 159-167
7. Boscha ME, Sánchezb A J, Rojasc FS, Ojedac CB. Ganciclovir: a review of its analytical determination. AJPS 2009; 4: 254-264
8. Reddy CM, Reddy GV. Determination of ganciclovir in bulk and pharmaceutical dosage forms by UV spectromphotometric method. Int Res J Pharm. 2012; 3: 286-288
9. Uslu B, Doğan B, Ozkan SA. Electrochemical studies of ganciclovir at glassy carbon electrodes and its direct determination in serum and pharmaceutics by square wave and differential pulse voltammetry. Anal chim acta 2005; 537: 307-313
10. 10. Sarsambi PS, Sonawane A, Faheem A. Development and validation of RP-HPLC method for the determination of ganciclovir in bulk drug and its formulations. Int J Pharm. Bio. Sci. 2010; 1: 1-7
11. 11. Ramesh PJ, Basavaiah K, Xavier CM, Prashanth KN, Raghu MS, Vinay KB. Titrimetric and Spectrophotometric Assay of Ganciclovir in Pharmaceuticals Using Cerium (IV) Sulphate as the Oxidimetric Agent. ISRN Anal Chem. 2012: 1-8
12. 12. Gouda AA, Amin AS. Utility of inorganic oxidants for the spectrophotometric determination of ganciclovir in dosage forms. Lat. Am. J. Pharm. 2011; 30: 334-341
13. 13. Gouda AA. Utility of certain sigma- and pi-acceptors for the spectrophotometric determination of ganciclovir in pharmaceutical formulations. Talanta 2009; 80: 151-157
14. 14. Al-Neaimy UI, Al-Delymi AMS. Visible Spectrophotometric Determination of Ganciclovir in its Pharmaceutical Formulations using Quinalizarin Reagent. Jord J Chem. 2013; 8: 103-112
15. 15. Kumar TA, Gurupadayya BM, Reddy MBR. Selective and Validated Spectrophotometric Assay for Microgram Determination of Ganciclovir with 1-fluoro-2, 4-dinitrobenzene and N-Bromosuccinimide Reagents. J Appl Chem Res. 2012; 20: 14-27
16. 16. Thomas OE, Adegoke OA. Development and validation of a new spectrophotometric method for the determination of acyclovir. J Pharmacy & Bioresources 2012; 9: 75-84
17. 17. Adegoke OA. Analytical, biochemical and synthetic applications of para-dimethylaminobenzaldehyde. Int J Pharm Sci Rev Res. 2011; 11: 17-29
18. 18. Karnes HT, March C. Precision, accuracy and data acceptance criteria in biopharmaceutical analysis. Pharm. Res. 1993; 10: 1420-1426
19. 19. Rose J. Advanced Physico-Chemical Experiments. London: Pitman; 1964 p. 52
20. 20. ICH Guidelines Q2 (R1). Validation of Analytical Procedures: Text and Methodology. Date accessed 20 June 2013
21. 21. United States Pharmacopoeia 30/National Formulary 25. Rockville,Md., USA, 2007
22. 22. Adegoke OA, Umoh OE. A new approach to the spectrophotometric determination of metronidazole and tinidazole using p- dimethylaminobenzaldehyde. Acta Pharm. 2009; 59: 407-419.