Determination of ganciclovir in human plasma by ultra performance liquid chromatography-UV detection

Clinical Biochemistry

Volumn 45, Issue 4-5, 2012, Pages 309-314

  Padulles A ^a   Colom, H ^b   Armendariz, Y ^a   Cerezo, G ^a   Caldes, A ^a   Pou, L ^c   Torras, J ^a   Grinyo J M ^a   Lloberas, N ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

Ganciclovir; HPLC; Therapeutic drug monitoring; UHPLC; Valganciclovir

Indexed keywords

GANCICLOVIR;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; GRAFT RECIPIENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; LIMIT OF QUANTITATION; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

ANTIVIRAL AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; GANCICLOVIR; HUMANS; LIMIT OF DETECTION; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84857655237     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2011.12.014     Document Type: Article

References (21)

1. Tolkoff-Rubin N.E., Rubin R.H. The impact of cytomegalovirus infections on graft function and patient outcome. Graft 1999, S101-S103.
2. Mc Gavin J.K., Goal K.L. Ganciclovir: an update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients. Drugs 2001, 61:1153-1183.
3. Information product of Ganciclovir.
4. Crumpacker C.S. Ganciclovir. N Eng J Med 1996, 335:721-729.
5. Pescovitz M.D., Rabkin J., Merino R., Paya C., Pirsch J., Freeman R.B., O'Grady J., Robinson C., Z.To, Wren K., Banken L., Buhles W., Brown F. Valganciclovir results in improved oral absorption of ganciclovir in liver transplant recipients. Antimicrob Agents Chemother 2000, 44:2811-281.
6. Pescovitz M.D., Pruett T.L., Gonwa T., Brook B., McGory R., Wicker K., Griffy K., Robinson C.A., Jung D. Oral ganciclovir dosing in transplant recipients and dialysis patients based on renal function. Transplantation 1998, 66:1104-1107.
7. Information product of Valganciclovir.
8. Wiltshire H., Hirankarn S., Farrell C., Paya C., Pescovitz M.D., Humar A., Domínguez E., Washburn K., Blumberg E., Alexander B., Freeman R., Heaton N. Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir in solid organ transplant recipients. Clin Pharmacokinet 2005, 44:495-507.
9. Wiltshire H., Paya C., Pescovitz M.D., Humar A., Domínguez E., Washburn K., Blumberg E., Alexander B., Freeman R., Heaton N., Zuideveld K.P. Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients. Transplantation 2005, 79:1477-1483.
10. Caldés A., Colom H., Armendariz Y., Garrido M.J., Trocóniz I.F., Gil-Vernet S., Lloberas N., Pou L., Peraire C., Grinyó J.M. Population pharmacokinetics of ganciclovir after intravenous ganciclovir and oral valganciclovir administration in solid organ transplant patients infected with cytomegalovirus. Antimicrob Agents Chemother 2009, 53:4816-4824.
11. Loregian A., Gatti R., Palú G., De Palo E. Separation method for acyclovir and related antiviral compounds. J Chromatogr B 2001, 764:289-311.
12. Campanero M.A., Sabada B., García-Quetglas E., Azanza J.R. Developement and validation of sensitive method for the determination of ganciclovir in human plasma samples by reversed-phase high-performance liquid chormatography,. J Chromatogr B 1998, 706:311-317.
13. Cociglio M., Peyriere H., Hillaire-Buys D., Alric R. Application of a standardized coextractive clean up procedure to routine high-performance liquid cromatography. J Chromatogr B 1998, 705:79-85.
14. Kishino S., Takekuma Y., Sugawara M., Furukawa H., Todo S., Miyazaki K. Liquid Chromathographic method for the determinationof acyclovir and/or acyclovir in human plasma using amperometric detection. J Chromatogr B 2002, 780:289-294.
15. Chu F., Kiang C.H., Sung M.L., Huang B., Reeve R.L., Tarnowski T. A rapid, sensitive HPLC method for the determination of ganciclovir in human plasma and serum. J Pharm Biomed Anal 1999, 21:657-667.
16. Teshima D., Otsubo K., Yoshida T., Itoh Y., Oishi R. A simple and simultaneous determination of acyclovir and ganciclovir in human plasma by high-performance liquid chormatography. Biomed Chromatogr 2003, 17:500-503.
17. Dao Y., Jiao Z., Zhong M. Simultaneous determination of aciclovir, ganciclovir, and penciclovir in human plasma by high-performance liquid chormatography with fluorescence detection. J Chromatogr B 2008, 867:270-276.
18. Asberg A., Nupen Hansen C., Reubsaet L. Determination of ganciclovir in different matrices from solid organ transplanted patients treated with a wide range of concomitant drugs. J Pharm Biomed Anal 2007, 43:1039-1044.
19. Pou L., Campos F., Almirante B., Pascual C. A rapid liquid chromatographic (HPLC) method for determination of ganciclovir in serum. Biologie prospective, Comptes rendus du 8° Colloque de Pont-a-Mousson 1993, 183-186. John Libbey Eurotext, Paris, France. M.M. Galteau, G. Siest, J. Henny (Eds.).
20. Guidance for industry, bioanalytical method validation U.S. department of health and human services Food and Drug administration center for Drug Evaluation and research (CDER) center for veterinary medicine (CVM) May 2001, BP.
21. Passing H., Bablok W. J Clin Chem Clin Biochem 1984, 22:431.