Neural response in obsessive-compulsive washers depends on individual fit of triggers

Frontiers in Human Neuroscience

Volumn , Issue APR 2013, 2013, Pages

  Baioui, Ali ^a   Pilgramm, Juliane ^a   Merz, Christian Josef ^a   Walter, Bertram ^a   Vaitl, Dieter ^a   Stark, Rudolf ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Basal ganglia; Contamination; fMRI; Individualization; OCD; Orbitofronto striatal network; Symptom provocation; Washers

Indexed keywords

ADULT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN REGION; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; EVOKED RESPONSE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLOBUS PALLIDUS; HUMAN; HYGIENE; MALE; NERVE CELL NETWORK; NEUROIMAGING; NUCLEUS ACCUMBENS; OBSESSIVE COMPULSIVE DISORDER; SYMPTOM;

EID: 84933670376     PISSN: 16625161     EISSN: 16625161     Source Type: Journal    
DOI: 10.3389/fnhum.2013.00143     Document Type: Article

References (59)

1. American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR., 4th edn., American Psychiatric Press, Washington, DC.
2. Baldi, E., and Bucherelli, C. (2005). The inverted u-shaped dose-effect relationships in learning and memory: modulation of arousal and consolidation: Nonlinearity in biology, toxicology, medicine. Nonlinearity Biol Toxicol Med 3 (1), 9-21. doi:10.2201 /nonlin.003.01.002.
3. Beck, A.T., Steer, R.A., Brown, G.K. (1996). Manual for Beck Depression Inventory-II, Psychological Corporation, San Antonio, TX.
4. Bloch, M.D., Landeros-Weisenberger, M.D., Rosario, M.D., Pittenger, M.D., and Leckman, M.D. (2008). Meta-Analysis of the Symptom Structure of Obsessive- Compulsive Disorder: American Journal of Psychiatry. Am J Psychiatry 165 (12), 1532-1542. doi:10.1176/appi.ajp.2008.08020320.
5. Chamberlain, S.R., Blackwell, A.D., Fineberg, N.A., Robbins, T.W., and Sahakian, B.J. (2005). The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. Neurosci Biobehav Rev 29 (3), 399-419.
6. Chen, X.-L., Xie, J.-X., Han, H.-B., Cui, Y.-H., and Zhang, B.-Q. (2004). MR perfusion weighted imaging and quantitative analysis of cerebral hemodynamics with symptom provocation in unmedicated patients with obsessive-compulsive disorder. Neurosci Lett 370 (2-3), 206-211.
7. Coles, M.E., Frost, R.O., Heimberg, R.G., and Rheaume, J. (2003). "Not just right experiences": perfectionism, obsessive-compulsive features and general psychopathology. Behav Res Ther 41 (6), 681-700.
8. Deckersbach, T., Dougherty, D.D., and Rauch, S.L. (2006). Functional imaging of mood and anxiety disorders. J Neuroimaging 16 (1), 1-10.
9. Deckersbach, T., Savage, C.R., Curran, T., Bohne, A., Wilhelm, S., Baer, L., Jenike, M.A., and Rauch, S.L. (2002). A study of parallel implicit and explicit information processing in patients with obsessive-compulsive disorder. Am J Psychiatry 159 (10), 1780.
10. Deichmann, R., Gottfried, J.A., Hutton, C., and Turner, R. (2003). Optimized EPI for fMRI studies of the orbitofrontal cortex. Neuroimage 19 (2 Pt 1), 430-441.
11. First, M.B., Gibbon, M., Spitzer, R.L., Williams, J.B., Benjamin, L. (1997a). Structured Clinical Interview for DSM-IV Personality Disorders (SCID-II): Interview and Questionnaire, American Psychiatric Press Washington, DC.
12. First, M.B., Spitzer, R.L., Gibbon, M., Williams, J.B.W. (1997b). Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinician Version, American Psychiatric Publishing, Inc, 88- pp.
13. Foa, E.B., Huppert, J.D., Leiberg, S., Langner, R., Kichic, R., Hajcak, G., and Salkovskis, P.M. (2002). The Obsessive-Compulsive Inventory: Development and Validation of a Short Version. Psychol Assess 14 (4), 485-496.
14. Friedlander, L., and Desrocher, M. (2006). Neuroimaging studies of obsessive- compulsive disorder in adults and children. Clin Psychol Rev 26 (1), 32-49.
15. Fydrich, T., Rennebergw, B., Schmitz, B., Wittchen, H.U. (1997). SKID. Strukturiertes Klinisches Interview für DSM-IV. Achse II: Persönlichkeitsstörungen, Hogrefe, Göttingen.
16. Gönner, S., Ecker, W., Leonhart, R. (2009). Obsessive-Compulsive Inventory- Revised (OCI-R). Deutsche Adaptation. Manual., Pearson Assessment & Information., Frankfurt am Main.
17. Gönner, S., Leonhart, R., and Ecker, W. (2007). Das Zwangsinventar OCI-R-die deutsche Version des Obsessive-Compulsive Inventory-Revised: Ein kurzes Selbstbeurteilungsinstrument zur mehrdimensionalen Messung von Zwangssymptomen. Psychother Psychosom Med Psychol 57, 395-404.
18. Goodman, W.K., Price, L.H., Rasmussen, S.A., Mazure, C., Delgado, P., Heninger, G.R., and Charney, D.S. (1989a). The Yale-Brown Obsessive Compulsive Scale. II. Validity. Arch Gen Psychiatry 46 (11), 1012-1016.
19. Goodman, W.K., Price, L.H., Rasmussen, S.A., Mazure, C., Fleischmann, R.L., Hill, L.,Heninger, G.R., and Charney, D.S. (1989b). The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry 46 (11), 1006-1011.
20. Greenberg, B.D., Gabriels, L.A., Malone, D.A., Jr, Rezai, A.R., Friehs, G.M., Okun, M.S., Shapira, N.A., Foote, K.D., Cosyns, P.R., Kubu, C.S., Malloy, P.F., Salloway, S.P., Giftakis, J.E., Rise, M.T., Machado, A.G., Baker, K.B., Stypulkowski, P.H., Goodman, W.K., Rasmussen, S.A., and Nuttin, B.J. (2010). Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience. Mol Psychiatry 15 (1), 64-79.
21. Guehl, D., Benazzouz, A., Aouizerate, B., Cuny, E., Rotge, J.-Y., Rougier, A., Tignol, J., Bioulac, B., and Burbaud, P. (2008). Neuronal Correlates of Obsessions in the Caudate Nucleus. Biol Psychiatry 63 (6), 557-562.
22. Hand, I., and Büttner-Westphal, H. (1991). Die Yale-Brown-Obsessive-Scale (Y-BOCS). Ein halbstrukturiertes Interview zur Beurteilung des Schweregrades von Denk-und Handlungszwängen. Verhaltenstherapie 1, 223-225.
23. Hasler, G., LaSalle-Ricci, V.H., Ronquillo, J.G., Crawley, S.A., Cochran, L.W., Kazuba, D., Greenberg, B.D., and Murphy, D.L. (2005). Obsessive-compulsive disorder symptom dimensions show specific relationships to psychiatric comorbidity. Psychiatry Res 135 (2), 121-132.
24. Hasler, G., Pinto, A., Greenberg, B.D., Samuels, J., Fyer, A.J., Pauls, D., Knowles, J.A., McCracken, J.T., Piacentini, J., Riddle, M.A., Rauch, S.L., Rasmussen, S.A., Willour, V.L., Grados, M.A., Cullen, B., Bienvenu, O.J., Shugart, Y.-Y., Liang, K.-y., Hoehn- Saric, R., Wang, Y., Ronquillo, J., Nestadt, G., and Murphy, D.L. (2007). Familiality of Factor Analysis-Derived YBOCS Dimensions in OCD-Affected Sibling Pairs from the OCD Collaborative Genetics Study. Biol Psychiatry 61 (5), 617-625. doi:10.1016/j.biopsych.2006.05.040.
25. Hautzinger, M., Keller, F., Kühner, C. (2006). BDI II-Beck Depressions-Inventar- Manual, Frankfurt am Main: Harcourt Test Services.
26. Huey, E.D., Zahn, R., Krueger, F., Moll, J., Kapogiannis, D., Wassermann, E.M., and Grafman, J. (2008). A psychological and neuroanatomical model of obsessive- compulsive disorder. J Neuropsychiatry Clin Neurosci 20 (4), 390-408.
27. Jones, M.K., and Menzies, R.G. (1997). The cognitive mediation of obsessive- compulsive handwashing. Behav Res Ther 35 (9), 843-850.
28. Lang, P.J., Bradley, M.M., Cuthbert, B.N. (2008). International affective picture system (iaps): Affective ratings of pictures and instruction manual, University of Florida, Gainesville.
29. Laux, L., Glanzmann, P., Schaffner, P., Spielberger, C.D. (1981). Das State-Trait- Angstinventar: STAI, Beltz, Weinheim.
30. Markarian, Y., Larson, M.J., Aldea, M.A., Baldwin, S.A., Good, D., Berkeljon, A., Murphy, T.K., Storch, E.A., and McKay, D. (2010). Multiple pathways to functional impairment in obsessive-compulsive disorder. Clin Psychol Rev 30 (1), 78-88.
31. Mataix-Cols, D., Cullen, S., Lange, K., Zelaya, F., Andrew, C., Amaro, E., Brammer, M.J., Williams, S.C.R., Speckens, A., and Phillips, M.L. (2003). Neural correlates of anxiety associated with obsessive-compulsive symptom dimensions in normal volunteers. Biol Psychiatry 53 (6), 482-493.
32. Mataix-Cols, D., do Rosario-Campos, M.C., and Leckman, J.F. (2005). A multidimensional model of obsessive-compulsive disorder. Am J Psychiatry 162 (2), 228.
33. Mataix-Cols, D., Lawrence, N.S., Wooderson, S., Speckens, A., and Phillips, M.L. (2009). The Maudsley Obsessive-Compulsive Stimuli Set: Validation of a standardized paradigm for symptom-specific provocation in obsessive-compulsive disorder. Psychiatry Res 168 (3), 238-241.
34. Mataix-Cols, D., Wooderson, S., Lawrence, N., Brammer, M.J., Speckens, A., and Phillips, M.L. (2004). Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder. Arch Gen Psychiatry 61 (6), 564-576.
35. Matsunaga, H., Hayashida, K., Kiriike, N., Maebayashi, K., and Stein, D. (2010). The clinical utility of symptom dimensions in obsessive-compulsive disorder. Psychiatry Res 180 (1), 25-29. doi:10.1016/j.psychres.2009.09.005.
36. McGuire, P.K., Bench, C.J., Frith, C.D., Marks, I.M., Frackowiak, R.S., and Dolan, R.J. (1994). Functional anatomy of obsessive-compulsive phenomena. Br J Psychiatry 164 (4), 459-468.
37. McKay, D., Abramowitz, J.S., Calamari, J.E., Kyrios, M., Radomsky, A., Sookman, D., Taylor, S., and Wilhelm, S. (2004). A critical evaluation of obsessive-compulsive disorder subtypes: Symptoms versus mechanisms. Clin Psychol Rev 24 (3), 283-313.
38. Menzies, L., Chamberlain, S.R., Laird, A.R., Thelen, S.M., Sahakian, B.J., and Bullmore, E. T. (2008). Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited. Neurosci Biobehav Rev 32 (3), 525-549.
39. Nakatani, E., Nakgawa, A., Ohara, Y., Goto, S., Uozumi, N., Iwakiri, M., Yamamoto, Y., Motomura, K., Iikura, Y., and Yamagami, T. (2003). Effects of behavior therapy on regional cerebral blood flow in obsessive-compulsive disorder. Psychiatry Res: Neuroimaging 124 (2), 113-120.
40. Phillips, M.L., Marks, I.M., Senior, C., Lythgoe, D., O'Dwyer, A.M., Meehan, O., Williams, S.C., Brammer, M.J., Bullmore, E.T., and McGuire, P.K. (2000). A differential neural response in obsessive-compulsive disorder patients with washing compared with checking symptoms to disgust. Psychol Med 30 (5), 1037-1050.
41. Pinto, A., Mancebo, M.C., Eisen, J.L., Pagano, M.E., and Rasmussen, S.A. (2006). The Brown Longitudinal Obsessive Compulsive Study: clinical features and symptoms of the sample at intake. J Clin Psychiatry 67 (5), 703-711.
42. Rauch, S.L., Shin, L.M., Dougherty, D.D., Alpert, N.M., Fischman, A.J., and Jenike, M.A. (2002). Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study. Neuropsychopharmacology 27 (5), 782-791.
43. Rotge, J.-Y., Guehl, D., Dilharreguy, B., Cuny, E., Tignol, J., Bioulac, B., Allard, M., Burbaud, P., and Aouizerate, B. (2008). Provocation of obsessive-compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies. J Psychiatry Neurosci 33 (5), 405-412.
44. Rozin, P., Millman, L., and Nemeroff, C. (1986). Operation of the laws of sympathetic magic in disgust and other domains. JPers Soc Psychol 50, 703-712.
45. Saxena, S., Brody, A.L., Schwartz, J.M., and Baxter, L.R. (1998). Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. Br J Psychiatry (35), 26-37.
46. Schienle, A., Schâfer, A., Stark, R., Walter, B., and Vaitl, D. (2005). Neural responses of OCD patients towards disorder-relevant, generally disgust-inducing and fear-inducing pictures. Int J Psychophysiol 57 (1), 69-77.
47. Schienle, A., Walter, B., Stark, R., and Vaitl, D. (2002). Ein Fragebogen zur Erfassung der Ekelempfindlichkeit (FEE). (A questionnaire for the assessment of disgust sensitivity QADS). Z Klin Psychol Psychother 31 (2), 110-120.
48. Schlaepfer, T.E., and Bewernick, B. (2011). Modulating affect, cognition, and behavior - prospects of deep brain stimulation for treatment-resistant psychiatric disorders. Front Integr Neurosci 5, 29.
49. Shapira, N.A., Liu, Y., He, A.G., Bradley, M.M., Lessig, M.C., James, G.A., Stein, D.J., Lang, P.J., and Goodman, W.K. (2003). Brain activation by disgust-inducing pictures in obsessive-compulsive disorder. Biol Psychiatry 54 (7), 751-756.
50. Simon, D., Kaufmann, C., Müsch, K., Kischkel, E., and Kathmann, N. (2010). Fronto striato limbic hyperactivation in obsessive compulsive disorder during individually tailored symptom provocation. Psychophysiology 47 (4), 728-738.
51. Spielberger, C.D., Gorsuch, R.L., Lushene, R.E. (1970). Manual for the State-Trait Anxiety Inventory, Consulting Psychologists Press, Palo Alto, CA.
52. Sturm, V., Lenartz, D., Koulousakis, A., Treuer, H., Herholz, K., Klein, J.C., and Klosterkötter, J. (2003). The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive- and anxiety-disorders. J Chem Neuroanat 26 (4), 293-299.
53. Summerfeldt, L.J., Richter, M.A., Antony, M.M., and Swinson, R.P. (1999). Symptom structure in obsessive-compulsive disorder: a confirmatory factor-analytic study. Behav Res Ther 37 (4), 297-311.
54. van den Heuvel, O.A., Remijnse, P.L., Mataix-Cols, D., Vrenken, H., Groenewegen, H.J., Uylings, H.B.M., van Balkom, A.J.L.M., and Veltman, D.J. (2009). The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems. Brain 132 (Pt 4), 853-868.
55. van den Heuvel, O.A., van der Werf, Y.D., Verhoef, K.M.W., Wit, S. de, Berendse, H.W., Wolters, E.C., Veltman, D.J., and Groenewegen, H.J. (2010). Frontal-striatal abnormalities underlying behaviours in the compulsive-impulsive spectrum. J Neurol Sci 289 (1-2), 55-59. doi:10.1016/j.jns.2009.08.043.
56. van den Heuvel, O.A., Veltman, D.J., Groenewegen, H.J., Dolan, R.J., Cath, D.C., Boellaard, R., Mesina, C.T., van Balkom, A.J.L.M., van Oppen, P., Witter, M.P., Lammertsma, A.A., and van Dyck, R. (2004). Amygdala activity in obsessive- compulsive disorder with contamination fear: a study with oxygen-15 water positron emission tomography. Psychiatry Res 132 (3), 225-237.
57. Wang, X., Cui, D., Wang, Z., Fan, Q., Xu, H., Qiu, J., Chen, J., Zhang, H., Jiang, K., and Xiao, Z. (2012). Cross-sectional comparison of the clinical characteristics of adults with early-onset and late-onset obsessive compulsive disorder. J Affect Disord 136 (3), 498-504. doi:10.1016/j.jad.2011.11.001.
58. Whiteside, S.P., Port, J.D., and Abramowitz, J.S. (2004). A meta-analysis of functional neuroimaging in obsessive-compulsive disorder. Psychiatry Res: Neuroimaging 132 (1), 69-79.
59. Wittchen, H.U., Wunderlich, U., Gruschwitz, S., Zaudig, M. (1997). SKID. Strukturiertes Klinisches Interview für DSM-IV. Achse I: Psychische Störungen, Hogrefe, Göttingen.