Genetically engineered insects-regulatory progress and challenges

Regulation of Agricultural Biotechnology: The United States and Canada

Volumn 9789400721562, Issue , 2012, Pages 281-299

  Alphey, Luke S ^a,b   Beech, Camilla J ^a  

^a OXITEC LIMITED   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Environmental Impact Statement; Genetically engineered insects; Plant pests; Regulation

Indexed keywords

CHROMOSOMES; ENVIRONMENTAL PROTECTION; ENVIRONMENTAL REGULATIONS; GENETIC ENGINEERING; PEST CONTROL;

ENVIRONMENTAL IMPACT STATEMENT; ENVIRONMENTAL PROTECTION ACTS; GENETICALLY ENGINEERED INSECTS; GENETICALLY ENGINEERED ORGANISMS; PLANT PESTS; RADIATION STERILIZATION; REGULATION; STERILE INSECT TECHNIQUES;

ENVIRONMENTAL IMPACT;

EID: 84933567376     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-94-007-2156-2_13     Document Type: Chapter

References (98)

1. Alphey L (2002) Re-engineering the sterile insect technique. Insect Biochem Mol Biol 32: 1243-1247
2. Alphey L (2007) Engineering insects for the sterile insect technique. In: Vreysen M, Robinson A, Hendrichs J (eds) Area-wide control of insect pests: from research to field implementation. Springer, Dordrecht, pp 51-60
3. Alphey L (2009) Natural and engineered mosquito immunity. J Biol 8:40
4. Alphey L, Andreasen MH (2002) Dominant lethality and insect population control. Mol Biochem Parasitol 121:173-178
5. Alphey L, Beard B, Billingsley P, Coetzee M, Crisanti A, Curtis CF, Eggleston P, Godfray C, Hemingway J, Jacobs-Lorena M et al (2002) Malaria control with genetically modi fied vectors. Science 298:119-121
6. Alphey L, Benedict MQ, Bellini R, Clark GG, Dame D, Service M, Dobson S (2010) Sterile-insect methods for control of mosquito-borne diseases-an analysis. Vector Borne Zoonotic Dis 10:295-311
7. Andreasen MH, Curtis CF (2005) Optimal life stage for radiation sterilization of Anopheles for sterile insect releases. Med Vet Entomol 19:238-244
8. Angulo E, Gilna B (2008) When biotech crosses borders. Nat Biotechnol 26:277-282
9. Antilla L, Liesner L (2008) Program advances in the eradication of pink bollworm, Pectinophora gossypiella, in Arizona cotton. Paper presented at 2008 Beltwide cotton conferences. National Cotton Council of America, Nashville
10. Atkinson MP, Su Z, Alphey N, Alphey LS, Coleman PG, Wein LM (2007) Analyzing the control of mosquito-borne diseases by a dominant lethal genetic system. Proc Natl Acad Sci USA 104:9540-9545
11. Bakri A, Mehta K, Lance DR (2005) Sterilizing insects with ionizing radiation. In: Dyck VA, Hendrichs J, Robinson AS (eds) Sterile insect technique: Principles and practice in area-wide integrated pest management. Springer, Dordrecht, pp 233-268, Available at http://www. springerlink. com/content/978-1-4020-4050-4/front-matter. pdf
12. Barclay HJ (2005) Mathematical models for the use of sterile insects. In: Dyck VA, Hendrichs J, Robinson AS (eds) Sterile insect technique: Principles and practice in area-wide integrated pest management. Springer, Dordrecht, pp 147-174, ISBN-10 1-4020-4050-4 (HB)
13. Beech C, Vasan S, Quinlan M, Capurro ML, Alphey L, Bayard V, Bouare M, Mcleod-Corena M, Kittaypong P, Lavery J et al (2009) Deployment of innovative genetic vector control strategies: progress on regulatory and biosafety aspects, capacity building and development of best practice guidance. Asia Pac J Mol Biol Biotechnol 17:75-85
14. Bellini R, Calvitti M, Medici A, Carrieri M, Celli G, Maini S (2007) Use of the sterile insect technique against Aedes albopictus in Italy: first results of a pilot trial. In: Vreysen MB, Robinson AS, Hendrichs J (eds) Area-wide control of insect pests. Springer, Dordrecht, pp 505-515
15. Benedict M, Eckerstorfer M, Franz G, Gaugitsch H, Greiter A, Heissenberger A, Knols B, Kumschick S, Nentwig W, Rabitsch W (2010) De fi ning environmental risk assessment criteria for genetically modi fied insects to be placed on the EU market. Environment Agency Austria (Umweltbundesamt), Available at http://www. efsa. europa. eu/en/supporting/doc/71e. pdf
16. Benedict MQ, Robinson AS (2003) The first releases of transgenic mosquitoes: An argument for the sterile insect technique. Trends Parasitol 19:349-355
17. Benedict MQ, Tabachnick WJ, Higgs S, Azad AF, Beard CB, Beier JC, Handler AM, James AA, Lord CC, Nasci RS, Olson KE et al (2003) Arthropod containment guidelines. Version 3. 1. Vector Borne Zoonotic Dis 3(2):57-98
18. Burt A (2003) Site-speci fi c sel fi sh genes as tools for the control and genetic engineering of natural populations. Proc Biol Sci 270:921-928
19. Burt A, Trivers R (2006) Genes in con fl ict: the biology of sel fi sh genetic elements. Belknap Press/Harvard University Press, Cambridge
20. Carpenter JE, Bloem S, Marec F (2005) Inherited sterility in insects. In: Dyck VA, Hendrichs J, Robinson AS (eds) Sterile insect technique: Principles and practice in area-wide integrated pest management. Springer, Dordrecht, pp 115-146, ISBN-13 978-1-4020-4050-4 (HB)
21. Catteruccia F, Benton J, Crisanti A (2005) An Anopheles transgenic sexing strain for vector control. Nat Biotechnol 23:1414-1417
22. Catteruccia F, Crisanti A, Wimmer E (2009) Transgenic technologies to induce sterility. Malar J 8:S7
23. Chen C-H, Huang H, Ward CM, Su JT, Schaeffer LV, Guo M, Hay BA (2007) A synthetic maternal-effect sel fi sh genetic element drives population replacement in Drosophila. Science 316:597-600
24. Condon K, Condon G, Dafa'alla T, Fu G, Phillips C, Jin L, Gong P, Alphey L (2007) Genetic sexing through the use of Y-linked transgenes. Insect Biochem Mol Biol 37:1168-1176
25. Corby-Harris V, Drexler A, Watkins de Jong L, Antonova Y, Pakpour N, Ziegler R, Ramberg F, Lewis EE, Brown JM, Luckhart S et al (2010) Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi Mosquitoes. PLoS Pathog 6:e1001003
26. Curtis C, Coleman PG, Kelly DW, Campbell-Lendrum DH (2006) Advantages and limitations of transgenic vector control: sterile males versus gene drivers. In: Boëte C (ed) Genetically modi fied mosquitoes for malaria control. Landes Bioscience, Austin
27. Dafa'alla T, Fu G, Alphey L (2010) Use of a regulatory mechanism of sex determination in pest insect control. J Genet 80:301-305
28. del Valle J (2003) New World screwworm (Cochliomyia hominivorax) in Mexico. Dis Inform 16:49-50
29. Deredec A, Burt A, Godfray H (2008) Population genetics of using homing endonuclease genes in vector and pest management. Genetics 179:2013-2026
30. Dyck VA, Hendrichs J, Robinson AS (eds) (2005) Sterile insect technique: Principles and practice in area-wide integrated pest management. Springer, Dordrecht, ISBN-10 1-4020-4051-2 (e-book)
31. Dye C (1984) Models for the population dynamics of the yellow fever mosquito, Aedes aegypti. J Anim Ecol 53:247-268
32. Fontes E (2009) Risk assessment and risk management under the Cartagena protocol on biosafety. Asia Pac J Mol Biol Biotechnol 17:97-98
33. Franz G (2005) Genetic sexing strains in Mediterranean fruit fl y, an example for other species amenable to large-scale rearing for the sterile insect technique. In: Dyck VA, Hendrichs J, Robinson AS (eds) Sterile insect technique: Principles and practice in area-wide integrated pest management. Published by Springer, Dordrecht, pp 427-451
34. Franz A, Sanchez-Vargas I, Adelman Z, Blair C, Beaty B, James A, Olson K (2006) Engineering RNA interference-based resistance to dengue virus type 2 in genetically modi fied Aedes aegypti. Proc Natl Acad Sci USA 103:4198-4203
35. Fryxell K, Miller T (1995) Autocidal biological control: A general strategy for insect control based on genetic transformation with a highly conserved gene. J Econ Entomol 88:1221-1232
36. Fu G, Condon KC, Epton MJ, Gong P, Jin L, Condon GC, Morrison NI, Dafa'alla TH, Alphey L (2007) Female-speci fi c insect lethality engineered using alternative splicing. Nat Biotechnol 25:353-357
37. Fu G, Lees RS, Nimmo D, Aw D, Jin L, Gray P, Berendonk TU, White-Cooper H, Scaife S, Kim Phuc H et al (2010) Female-speci fi c fl ightless phenotype for mosquito control. Proc Natl Acad Sci USA 107:4550-4554
38. Gong P, Epton M, Fu G, Scaife S, Hiscox A, Condon K, Condon G, Morrison N, Kelly D, Dafa'alla T et al (2005) A dominant lethal genetic system for autocidal control of the Mediterranean fruit fl y. Nat Biotechnol 23:453-456
39. Gould F, Huang Y, Legros M, Lloyd A (2008) A killer-rescue system for self-limiting gene drive of anti-pathogen constructs. Proc R Soc B 275:2823-2829
40. Graham HM, Mangum GL (1971) Larval diets containing dyes for tagging pink bollworm. J Econ Entomol 64:377-379
41. Grefenstette B, El-Lissy O, Staten RT (2009) Pink bollworm eradication plan in the US (USDAAPHIS), Available at http://www. aphis. usda. gov/plant-health/plant-pest-info/cotton- pests/downloads/pbw-erad-plan2-09. pdf
42. Hagler JR, Miller E (2002) An alternative to conventional insect marking techniques: detection of a protein mark of pink bollworm by ELISA. Entomol Exp Appl 103:1-9
43. Handler A (2002) Prospects for using genetic transformation for improved SIT and new biocontrol methods. Genetica 116:137-149
44. Handler A, James A (2000) Insect transgenesis: methods and applications. CRC Press, Boca Raton
45. Harris AF, Nimmo D, McKemey AR, Kelly N, Scaife S, Beech C, Petrie W, Alphey L (2011) Field performance of engineered male mosquitoes. Nat Biotechnol 29(11):1034-1037
46. Hedges LM, Brownlie JC, O'Neill SL, Johnson KN (2008) Wolbachia and virus protection in insects. Science 322:702
47. Heinrich J, Scott M (2000) A repressible female-speci fi c lethal genetic system for making transgenic insect strains suitable for a sterile-release program. Proc Natl Acad Sci USA 97: 8229-8232
48. Helinski M, Parker A, Knols BGJ (2006) Radiation-induced sterility for pupal and adult stages of the malaria mosquito Anopheles arabiensis. Malar J 5:41
49. Helinski MEH, Hassan MM, El-Motasim WM, Malcolm CA, Knols BGJ, El-Sayed B (2008) Towards a sterile insect technique field release of Anopheles arabiensis mosquitoes in Sudan: Irradiation, transportation, and field cage experimentation. Malar J 7:65
50. Higgs S (2004) The containment of arthropod vectors. University Press of Colorado, Niwot
51. Hirata MH, Filho JM (2002) Manual de Biossegurança. Manole, Sâo Paulo, p 466
52. Houck M, Clark J, Peterson K, Kidwell M (1991) Possible horizontal transfer of Drosophila genes by the mite Proctolaelaps regalis. Science 253:1125-1128
53. IAEA (2006) Status and risk assessment of the use of transgenic arthropods in plant protection. Paper presented at: proceedings of a technical meeting organised by the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture and the Secretariat of the International Plant Protection Convention, Rome
54. Ito J, Ghosh A, Moreira LA, Wimmer EA, Jacobs-Lorena M (2002) Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite. Nature 417:452-455
55. Kambris Z, Cook PE, Phuc HK, Sinkins SP (2009) Immune activation by life-shortening Wolbachia and reduced fi larial competence in mosquitoes. Science 326:134-136
56. Klassen W (2009) Introduction: development of the sterile insect technique for African malaria vectors. Malar J 8:I1
57. Knipling EF (1955) Possibilities of insect control or eradication through the use of sexually sterile males. J Econ Entomol 48:459-469
58. Knols BG, Louis C, Bogers RJ (2004) Bridging laboratory and field research for genetic control of disease vectors. Paper presented at Joint WHO/TDR, NIAID, IAEA and Frontis workshop on bridging laboratory and field research for genetic control of disease vectors, Nairobi
59. Kokoza V, Ahmed A, Cho W-L, Jasinskiene N, James A, Raikhel A (2000) Engineering blood meal-activated systemic immunity in the yellow fever mosquito, Aedes aegypti. Proc Natl Acad Sci USA 97:9144-9149
60. Lee H, Vasan S, Nazni W, Shanaz M (2008) Scientific report on the innovative application of Aedes aegypti RIDL-sterile insect technique to combat dengue and chikungunya in Malaysia. Institute of Medical Research, Kuala Lumpur
61. Lee HL, Joko H, Nazni WA, Vasan SS (2009) Comparative life parameters of transgenic and wild strain of Aedes aegypti in the laboratory. Dengue Bull 33:103-114
62. Legros M, Lloyd AL, Huang Y, Gould F (2009) Density-dependent intraspeci fi c competition in the larval stage of Aedes aegypti (Diptera: Culicidae): revisiting the current paradigm. J Med Entomol 46:409-419
63. Loukeris TG, Livadaras I, Arca B, Zabalou S, Savakis C (1995) Gene transfer into the med fl y, Ceratitis capitata, with a Drosophila hydei transposable element. Science 270:2002-2005
64. Marrelli MT, Moreira CK, Kelly D, Alphey L, Jacobs-Lorena M (2006) Mosquito transgenesis: what is the fi tness cost? Trends Parasitol 22:197-202
65. Marshall JM (2010) The Cartagena protocol and genetically modi fied mosquitoes. Nat Biotechnol 28:896-897
66. Moreira LA, Iturbe-Ormaetxe I, Jeffery JA, Lu G, Pyke AT, Hedges LM, Rocha BC, Hall-Mendelin S, Day A, Riegler M et al (2009) A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium. Cell 139:1268-1278
67. Morrison NI, Segura DF, Stainton KC, Fu G, Donnelly CA, Alphey LS (2009) Sexual competitiveness of a transgenic sexing strain of the Mediterranean fruit fl y, Ceratitis capitata. Entomol Exp Appl 133:146-153
68. Morrison NI, Franz G, Koukidou M, Miller TA, Saccone G, Alphey LS, Beech CJ, Nagaraju J, Simmons GS, Polito LC (2011) Genetic improvements to the sterile insect technique for agricultural pests. Asia Pac J Mol Biol Biotechnol 18:275-295
69. Murphy B, Jansen C, Murray J, De Barro P (2010) Risk analysis on the Australian release of Aedes aegypti (L) containing Wolbachia. CSIRO, Canberra, Australia, p 103, P. O. Box 17, 3300 AA Dordrecht, The Netherlands
70. NAS (1987) Introduction of recombinant DNA-engineered organisms into the environment: key issues. National Academies Press, Washington
71. DC Office of the Gene Technology Regulator (OGTR) (2006) Guidelines for the certi fi cation of a physical containment level 2 arthropod facility. Version 2. 1, Available at http://www. health. gov. au/internet/ogtr/publishing. nsf/Content/PC2-7/dollerFILE/PC2ARTHv2-1. rtf
72. Papathanos P, Bossin H, Benedict M, Catteruccia F, Malcolm C, Alphey L, Crisanti A (2009) Sex separation strategies: past experience and new approaches. Malar J 8:S5
73. Peloquin JJ, Thibault ST, Staten R, Miller TA (2000) Germ-line transformation of pink bollworm (Lepidoptera: Gelechiidae) mediated by the piggyBac transposable element. Insect Mol Biol 9:323-333
74. Pew Initiative on Food and Biotechnology (2004) Bugs in the system? Pew Initiative on Food and Biotechnology, Washington, DC, USA, Available at www. springeronline. com
75. Phuc HK, Andreasen MH, Burton RS, Vass C, Epton MJ, Pape G, Fu G, Condon KC, Scaife S, Donnelly CA et al (2007) Late-acting dominant lethal genetic systems and mosquito control. BMC Biol 5:11
76. Rasgon JL (2009) Multi-Locus Assortment (MLA) for transgene dispersal and elimination in mosquito populations. PLoS One 4:e5833
77. Rendón P, McInnis D, Lance D, Stewart J (2004) Med fl y (Diptera: Tephritidae) genetic sexing: large-scale field comparison of males-only and bisexual sterile fl y releases in Guatemala. J Econ Entomol 97:1547-1553
78. Rose R (2009) A short note on the final environmental impact statement-October 2008: use of genetically engineered fruit fl y and pink bollworm in APHIS plant pest control programs. Asia Pac J Mol Biol Biotechnol 17:85-89
79. Rubin G, Spradling A (1982) Genetic transformation of Drosophila with transposable element vectors. Science 218:3448-3453
80. Schetelig M, Caceres C, Zacharopoulou A, Franz G, Wimmer EA (2009) Conditional embryonic lethality to improve the sterile insect technique in Ceratitis capitata (Diptera: Tephritidae). BMC Biol 7:4
81. Scolari F, Siciliano P, Gabrieli P, Gomulski L, Bonomi A, Gasperi G, Malacrida A (2011) Safe and fi t genetically modi fied insects for pest control: from lab to field applications. Genetica 139:41-52
82. Scott TW (2005) Containment of arthropod disease vectors. Inst Lab Anim Res J 46(1):53-61
83. Silva J, Kidwell M (2000) Horizontal transfer and selection in the evolution of P elements. Mol Biol Evol 17:1542-1557
84. Simmons G, Alphey L, Vasquez T, Morrison N, Epton M, Miller E, Miller T, Staten R (2007) Potential use of a conditional lethal transgenic pink bollworm Pectinophora gossypiella in area-wide eradication or suppression programmes. In: Vreysen MB, Robinson AS, Hendrichs J (eds) Area-wide control of insect pests. Springer, Dordrecht, pp 119-123
85. Simmons GS, McKemey AR, Morrison NI, O'Connell S, Tabashnik BE, Claus J, Fu G, Tang G, Sledge M, Walker AS et al (2011) Field performance of a genetically engineered strain of pink bollworm. PLoS One 6(9):e24110
86. Sinkins S, Gould F (2006) Gene drive systems for insect disease vectors. Nat Rev Genet 7:427-435
87. Spradling A, Rubin G (1982) Transposition of cloned P elements into Drosophila germ line chromosomes. Science 218:341-347
88. Tabashnik BE, Sisterson MS, Ellsworth PC, Dennehy TJ, Antilla L, Liesner L, Whitlow M, Staten RT, Fabrick JA, Unnithan GC et al (2010) Suppressing resistance to Bt cotton with sterile insect releases. Nat Biotechnol 28:1304-1307
89. Takken W, Costantini C (2006) The genetics of vector-host interactions: Alternative strategies for genetic engineering for malaria control. In: Boëte C (ed) Genetically modi fied mosquitoes for malaria control. Landes Bioscience, Austin
90. Takken W, Scott TW, Bogers RJ (2002) Ecological aspects for application of genetically modi fied mosquitoes. Paper presented at Frontis workshop on ecological challenges concerning the use of genetically modi fied mosquitoes for disease control, Wageningen
91. Thomas DD, Donnelly CA, Wood RJ, Alphey LS (2000) Insect population control using a dominant, repressible, lethal genetic system. Science 287:2474-2476
92. US Office of Science and Technology Policy (OSTP) (1986) Coordinated framework for regulation of biotechnology: Announcement of policy and notice for public comment. Fed Regist:203-223, 393
93. USDA (2012) Determinations of non-regulated status (online) Available at http://www. aphis. usda. gov/biotechnology/not-reg. html. Accessed 28 June 2012
94. WHO (2009) Planning meetings on progress and prospects for the use of genetically modi fied mosquitoes to prevent disease transmission: meeting 1 technical consultations on the current status and planning for future development, Geneva
95. WHO/TDR (1991) Report of the meeting "Prospects for malaria control by genetic manipulation of its vectors". Paper presented at Vector biology meeting, Tuscon, Arizona, TDR/BCV/MAL-ENT/91
96. Windbichler N, Papathanos PA, Crisanti A (2008) Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae. PLoS Genet 4:e1000291
97. Wise de Valdez MR, Nimmo D, Betz J, Gong H-F, James AA, Alphey L, Black WC IV (2011) Genetic elimination of dengue vector mosquitoes. In: Proceedings of the National Academy of Sciences (USA) published ahead of print 7 Mar 2011
98. Yakob L, Alphey L, Bonsall M (2008) Aedes aegypti control: the concomitant role of competition, space and transgenic technologies. J Appl Ecol 45:1258-1265