Optimization of PEGylated nanoemulsions for improved pharmacokinetics of BCS class II compounds

Drug Delivery

Volumn 22, Issue 4, 2015, Pages 467-474

  Devalapally, Harikrishna ^a   Zhou, Feng ^a   McDade, Jessica ^a   Goloverda, Galina ^b   Owen, Albert ^a   Hidalgo, Ismael J ^a   Silchenko, Svitlana ^a  

^a Absorption Systems   (United States)

^b XAVIER UNIVERSITY OF LOUISIANA   (United States)

Author keywords

Clearance; danazol; nanoemulsion; PEGylation; phagocytosis

Indexed keywords

1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N METHOXY POLY(POLYETHYLENE GLYCOL 10000; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N METHOXY POLY(POLYETHYLENE GLYCOL 2000; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N METHOXY POLY(POLYETHYLENE GLYCOL 5000; DANAZOL; ETHANOLAMINE; MACROGOL; UNCLASSIFIED DRUG; DRUG CARRIER; EMULSION; MACROGOL DERIVATIVE; NANOPARTICLE; PHOSPHATIDYLETHANOLAMINE; POLYETHYLENE GLYCOL-DISTEAROYLPHOSPHATIDYLETHANOLAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; LUNG ALVEOLUS MACROPHAGE; MALE; NANOEMULSION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; VOLUME OF DISTRIBUTION; ANIMAL; CHEMICAL PHENOMENA; CHEMISTRY; COMPARATIVE STUDY; DRUG DELIVERY SYSTEM; EMULSION; INTRAVENOUS DRUG ADMINISTRATION; MACROPHAGE; MEDICINAL CHEMISTRY; METABOLISM; PARTICLE SIZE; PHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ADMINISTRATION, INTRAVENOUS; ANIMALS; CHEMISTRY, PHARMACEUTICAL; DANAZOL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMULSIONS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MACROPHAGES; MALE; NANOPARTICLES; PARTICLE SIZE; PHAGOCYTOSIS; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TISSUE DISTRIBUTION;

EID: 84933526790     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.869275     Document Type: Article

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