Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure

Journal of Cellular and Molecular Medicine

Volumn 19, Issue 7, 2015, Pages 1710-1719

  Yu, Peng ^a   Zhang, Yangyang ^a   Li, Chuanfu ^b   Li, Yuehua ^c   Jiang, Surong ^a   Zhang, Xiaojin ^a   Ding, Zhengnian ^a   Tu, Fei ^a   Wu, Jun ^a   Gao, Xiang ^d   Li, Liu ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b East Tennessee State University   (United States)

^c NANJING MEDICAL UNIVERSITY   (China)

^d NANJING UNIVERSITY   (China)

Author keywords

Autophagy; Cardiac hypertrophy; Class III PI3K Vps34; Heart failure; Heat shock protein 27

Indexed keywords

MUS; MUS MUSCULUS;

ANDROSTANE DERIVATIVE; APOPTOSIS REGULATORY PROTEIN; BECLIN 1; BECN1 PROTEIN, MOUSE; HEAT SHOCK PROTEIN 27; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; WORTMANNIN;

ANIMAL; AUTOPHAGY; CARDIOMEGALY; COMPLICATION; DIAGNOSTIC IMAGING; DRUG EFFECTS; ECHOGRAPHY; ENZYMOLOGY; HEART FAILURE; HEART FUNCTION TEST; HUMAN; METABOLISM; MITOCHONDRION; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; UPREGULATION;

ANDROSTADIENES; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; CARDIOMEGALY; HEART FAILURE; HEART FUNCTION TESTS; HSP27 HEAT-SHOCK PROTEINS; HUMANS; MICE, TRANSGENIC; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; REAL-TIME POLYMERASE CHAIN REACTION; ULTRASONOGRAPHY; UP-REGULATION;

EID: 84933278289     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12547     Document Type: Article

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