Recombinant interleukin 6 with M cell-targeting moiety produced in Lactococcus lactis IL1403 as a potent mucosal adjuvant for peroral immunization

Vaccine

Volumn 33, Issue 16, 2015, Pages 1959-1967

  Li, Hui Shan ^a   Piao, Da Chuan ^a   Jiang, Tao ^a   Bok, Jin Duck ^b   Cho, Chong Su ^a   Lee, Yoon Seok ^b   Kang, Sang Kee ^b   Choi, Yun Jaie ^a  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Adjuvant; Interleukin 6; Lactococcus lactis IL1403; M cell targeting peptide; Mucosal immune response; Peroral vaccination

Indexed keywords

CKS9 PEPTIDE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOLOGICAL ADJUVANT; MEMBRANE PROTEIN; RECOMBINANT INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 6 CKS9 PEPTIDE; UNCLASSIFIED DRUG; HYBRID PROTEIN; INTERLEUKIN 6; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACTERIAL STRAIN; BIOLOGICAL ACTIVITY; BIOTECHNOLOGICAL PRODUCTION; BRACHYSPIRA; CARBOXY TERMINAL SEQUENCE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG POTENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE EXPRESSION SYSTEM; HOST CELL; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; LACTOCOCCUS LACTIS; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; ANIMAL; BIOSYNTHESIS; GENE ORDER; GENE VECTOR; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; ORAL DRUG ADMINISTRATION; PEYER PATCH;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; FEMALE; GENE EXPRESSION; GENE ORDER; GENETIC VECTORS; IMMUNE TOLERANCE; IMMUNITY, MUCOSAL; IMMUNIZATION; INTERLEUKIN-6; INTESTINAL MUCOSA; LACTOCOCCUS LACTIS; MICE; PEPTIDES; PEYER'S PATCHES; RECOMBINANT FUSION PROTEINS;

EID: 84933177838     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.02.061     Document Type: Article

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