Osteopontin promotes dendritic cell maturation and function in response to HBV antigens

Drug Design, Development and Therapy

Volumn 9, Issue , 2015, Pages 3003-3016

  Cui, Guangying ^a,b   Chen, Jianing ^a,b   He, Jianqin ^a,b   Lu, Chong ^a,b   Wei, Yingfeng ^a,b   Wang, Lin ^a,b   Xu, Xuejun ^c   Li, Lanjuan ^a,b   Uede, Toshimitsu ^d   Diao, Hongyan ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Dendritic cells; Hepatitis B virus; Osteopontin

Indexed keywords

HEPATITIS ANTIGEN; INTERLEUKIN 12; OSTEOPONTIN; GLYCOPROTEIN P 15095; HEPATITIS B ANTIGEN; HEPATITIS B(E) ANTIGEN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL MATURATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; ADOPTIVE TRANSFER; ANIMAL; BIOSYNTHESIS; BLOOD; BONE MARROW CELL; C57BL MOUSE; COCULTURE; DRUG EFFECTS; GENETICS; HEPATITIS C; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MONOCYTE; PATHOLOGY;

ADOPTIVE TRANSFER; ADULT; ANIMALS; ANTIGENS, CD11C; BONE MARROW CELLS; COCULTURE TECHNIQUES; DENDRITIC CELLS; FEMALE; HEPATITIS B ANTIGENS; HEPATITIS B E ANTIGENS; HEPATITIS C; HUMANS; INTERLEUKIN-12; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; OSTEOPONTIN; TH1 CELLS;

EID: 84933074030     PISSN: None     EISSN: 11778881     Source Type: Journal    
DOI: 10.2147/DDDT.S81656     Document Type: Article

References (43)

1. WHO.int [World Health Organization]. Hepatitis B; 2015 [updated March, 2015]. Available from: http://www.who.int/mediacentre/factsheets/fs204/en/. Accessed March 21, 2015.
2. Lv G, Ying L, Ma WJ, et al. Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment. Virol J. 2010;7:207.
3. Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol. 2005;5:215-229.
4. Chen L, Zhang Z, Chen W, et al. B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B. J Immunol. 2007;178:6634-6641.
5. Zhang Z, Zou ZS, Fu JL, et al. Severe dendritic cell perturbation is actively involved in the pathogenesis of acute-on-chronic hepatitis B liver failure. J Hepatol. 2008;49:396-406.
6. van der Molen RG, Sprengers D, Binda RS, et al. Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B. Hepatology. 2004;40:738-746.
7. Löhr HF, Pingel S, Böcher WO, et al. Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B - restoration by exogenous interleukin-12. Clin Exp Immunol. 2002;130:107-114.
8. Cui GY, Diao HY. Recognition of HBV antigens and HBV DNA by dendritic cells. Hepatobiliary Pancreat Dis Int. 2010;9:584-592.
9. Kalinski P, Hilkens CM, Wierenga EA, Kapsenberg ML. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol Today. 1999;20:561-567.
10. Yamane H, Paul WE. Cytokines of the gamma(c) family control CD4+ T cell differentiation and function. Nat Immunol. 2012;13:1037-1044.
11. Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol. 2002;2:933-944.
12. Lanzavecchia A, Sallusto F. Regulation of T cell immunity by dendritic cells. Cell. 2001;106:263-266.
13. Nouri-Shirazi M, Kahlden C, Nishino P, Guinet E. Nicotine exposure alters the mRNA expression of Notch ligands in dendritic cells and their response to Th1-/Th2-promoting stimuli. Scand J Immunol. 2015;81:110-120.
14. Li L, Lee HH, Bell JJ, et al. IL-4 utilizes an alternative receptor to drive apoptosis of Th1 cells and skews neonatal immunity toward Th2. Immunity. 2004;20:429-440.
15. Zhu J, Jankovic D, Oler AJ, et al. The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses. Immunity. 2012;37:660-673.
16. Zhang S, Saha B, Kodys K, Szabo G. IFN-gamma production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells. J Hepatol. 2013;59:442-449.
17. Jimenez F, Quinones MP, Martinez HG, et al. CCR2 plays a critical role in dendritic cell maturation: possible role of CCL2 and NF-kappa B. J Immunol. 2010;184:5571-5581.
18. Marim FM, Silveira TN, Lima DS Jr, Zamboni DS. A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells. PLoS One. 2010;5:e15263.
19. He D, Yan G, Wang Y. Serum levels of interleukin-12 in various clinical states with hepatitis B virus infection. Cell Immunol. 2012;272:162-165.
20. Chen M, Li YG, Zhang DZ, et al. Therapeutic effect of autologous dendritic cell vaccine on patients with chronic hepatitis B: a clinical study. World J Gastroenterol. 2005;11:1806-1808.
21. Akbar SM, Furukawa S, Horiike N, Onji M. Vaccine therapy for hepatitis B virus carrier. Curr Drug Targets Infect Disord. 2004;4:93-101.
22. Luo J, Li J, Chen RL, et al. Autologus dendritic cell vaccine for chronic hepatitis B carriers: a pilot, open label, clinical trial in human volunteers. Vaccine. 2010;28:2497-2504.
23. Diao H, Kon S, Iwabuchi K, et al. Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases. Immunity. 2004;21:539-550.
24. Liu Y, Lu X, Yu HJ, et al. The expression of osteopontin and its association with Clara cell 10 kDa protein in allergic rhinitis. Clin Exp Allergy. 2010;40:1632-1641.
25. Kawamura K, Iyonaga K, Ichiyasu H, Nagano J, Suga M, Sasaki Y. Differentiation, maturation, and survival of dendritic cells by osteopontin regulation. Clin Diagn Lab Immunol. 2005;12:206-212.
26. Shinohara ML, Kim JH, Garcia VA, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008;29:68-78.
27. Hardie WD, Korfhagen TR, Sartor MA, et al. Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2007;37:309-321.
28. Takafuji V, Forgues M, Unsworth E, Goldsmith P, Wang XW. An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma. Oncogene. 2007;26:6361-6371.
29. Xu XW, Lu MH, Tan DM. Association between tumour necrosis factor gene polymorphisms and the clinical types of patients with chronic hepatitis B virus infection. Clin Microbiol Infect. 2005;11:52-56.
30. Sells MA, Chen ML, Acs G. Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA. Proc Natl Acad Sci U S A. 1987;84:1005-1009.
31. Inaba K, Inaba M, Romani N, et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med. 1992;176:1693-1702.
32. Park ES, Park YK, Shin CY, et al. Hepatitis B virus inhibits liver regeneration via epigenetic regulation of urokinase-type plasminogen activator. Hepatology. 2013;58:762-776.
33. Renkl AC, Wussler J, Ahrens T, et al. Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype. Blood. 2005;106:946-955.
34. Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H. T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A. 2005;102:17101-17106.
35. Zhao F, Zhang Y, Wang H, et al. Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease. Blood. 2011;117:1723-1733.
36. Diao H, Iwabuchi K, Li L, et al. Osteopontin regulates development and function of invariant natural killer T cells. Proc Natl Acad Sci U S A. 2008;105:15884-15889.
37. Frikeche J, Simon T, Brissot E, Grégoire M, Gaugler B, Mohty M. Impact of valproic acid on dendritic cells function. Immunobiology. 2012;217:704-710.
38. Löhr HF, Krug S, Herr W, et al. Quantitative and functional analysis of core-specific T-helper cell and CTL activities in acute and chronic hepatitis B. Liver. 1998;18:405-413.
39. Pei J, Tang Z, Zang G, Yu Y. Blockage of Notch1 signaling modulates the T-helper (Th)1/Th2 cell balance in chronic hepatitis B patients. Hepatol Res. 2010;40:799-805.
40. Khan S, Bhargava A, Pathak N, Maudar KK, Varshney S, Mishra PK. Circulating biomarkers and their possible role in pathogenesis of chronic hepatitis B and C viral infections. Indian J Clin Biochem. 2011;26:161-168.
41. Akbar SK, Horiike N, Onji M. Prognostic importance of antigen-presenting dendritic cells during vaccine therapy in a murine hepatitis B virus carrier. Immunology. 1999;96:98-108.
42. Farag MM, Hoyler B, Encke J, Stremmel W, Weigand K. Dendritic cells can effectively be pulsed by HBVsvp and induce specific immune reactions in mice. Vaccine. 2010;29:200-206.
43. Op den Brouw ML, Binda RS, van Roosmalen MH, et al. Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology. 2009;126:280-289.