Formulation optimization and in vitro skin penetration of spironolactone loaded solid lipid nanoparticles

Colloids and Surfaces B: Biointerfaces

Volumn 128, Issue , 2015, Pages 473-479

  Kelidari, H R ^a   Saeedi, M ^b   Akbari, J ^b   Morteza Semnani, K ^b   Gill, P ^b   Valizadeh, H ^c   Nokhodchi, A ^c,d  

^a MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Acne; Dermal delivery; Solid lipid nanoparticles (SLNs); Spironolactone

Indexed keywords

DIFFERENTIAL SCANNING CALORIMETRY; DRUG PRODUCTS; EMULSIFICATION; HYDROGEN BONDS; NANOPARTICLES; SCANNING TUNNELING MICROSCOPY;

ACNE; DERMAL DELIVERY; EMULSION-SOLVENT EVAPORATION METHOD; FORMULATION OPTIMIZATION; HYDROGEN BOND INTERACTION; SOLID LIPID NANOPARTICLE (SLN); SOLID LIPID NANOPARTICLES; SPIRONOLACTONE;

PHOTON CORRELATION SPECTROSCOPY;

DIURETIC AGENT; NANOPARTICLE; POLYSORBATE; SPIRONOLACTONE; STEARIC ACID; STEARIC ACID DERIVATIVE;

ANIMAL; CHEMISTRY; DIFFUSION CHAMBER; DRUG FORMULATION; DRUG RELEASE; HYDROGEN BOND; INTRADERMAL DRUG ADMINISTRATION; KINETICS; MALE; METABOLISM; PERMEABILITY; RAT; SKIN; SKIN ABSORPTION; ULTRASTRUCTURE; WISTAR RAT;

ADMINISTRATION, CUTANEOUS; ANIMALS; DIFFUSION CHAMBERS, CULTURE; DIURETICS; DRUG COMPOUNDING; DRUG LIBERATION; HYDROGEN BONDING; KINETICS; MALE; NANOPARTICLES; PERMEABILITY; POLYSORBATES; RATS; RATS, WISTAR; SKIN; SKIN ABSORPTION; SPIRONOLACTONE; STEARIC ACIDS;

EID: 84933033994     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.02.046     Document Type: Article

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