메뉴 건너뛰기




Volumn 47, Issue 2, 2015, Pages 690-700

CXCL5/CXCR2 axis promotes bladder cancer cell migration and invasion by activating PI3K/AKT-induced upregulation of MMP2/MMP9

Author keywords

Bladder cancer; CXCL5; CXCR2; Invasion; Migration; MMP2; MMP9; PI3K AKT

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GELATINASE A; GELATINASE B; PHOSPHATIDYLINOSITOL 3 KINASE; CXCL5 PROTEIN, HUMAN; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; PROTEIN KINASE B;

EID: 84932607211     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.3041     Document Type: Article
Times cited : (122)

References (30)
  • 1
    • 84899124772 scopus 로고    scopus 로고
    • The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: A meta-analysis
    • Yan Y, Liang H, Li T, Li M, Li R, Qin X and Li S: The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: A meta-analysis. Tumour Biol 35: 3047-3052, 2014.
    • (2014) Tumour Biol , vol.35 , pp. 3047-3052
    • Yan, Y.1    Liang, H.2    Li, T.3    Li, M.4    Li, R.5    Qin, X.6    Li, S.7
  • 2
    • 84897022815 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of urothelial bladder carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network: Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 507: 315-322, 2014.
    • (2014) Nature , vol.507 , pp. 315-322
  • 3
    • 0035258013 scopus 로고    scopus 로고
    • Matrix metalloproteinases and bladder cancer
    • Kanayama H: Matrix metalloproteinases and bladder cancer. J Med Invest 48: 31-43, 2001.
    • (2001) J Med Invest , vol.48 , pp. 31-43
    • Kanayama, H.1
  • 5
    • 0037942829 scopus 로고    scopus 로고
    • Differential regulation of lipopolysaccharide-induced monocyte matrix metalloproteinase (MMP)-1 and MMP-9 by p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases
    • Lai WC, Zhou M, Shankavaram U, Peng G and Wahl LM: Differential regulation of lipopolysaccharide-induced monocyte matrix metalloproteinase (MMP)-1 and MMP-9 by p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. J Immunol 170: 6244-6249, 2003.
    • (2003) J Immunol , vol.170 , pp. 6244-6249
    • Lai, W.C.1    Zhou, M.2    Shankavaram, U.3    Peng, G.4    Wahl, L.M.5
  • 6
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J and Kähäri VM: Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 13: 781-792, 1999.
    • (1999) FASEB J , vol.13 , pp. 781-792
    • Westermarck, J.1    Kähäri, V.M.2
  • 7
    • 7744229935 scopus 로고    scopus 로고
    • Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: Involvement of invasive potential
    • Chung TW, Lee YC and Kim CH: Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: Involvement of invasive potential. FASEB J 18: 1123-1125, 2004.
    • (2004) FASEB J , vol.18 , pp. 1123-1125
    • Chung, T.W.1    Lee, Y.C.2    Kim, C.H.3
  • 8
    • 33750890673 scopus 로고    scopus 로고
    • Radiationenhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway
    • Cheng JC, Chou CH, Kuo ML and Hsieh CY: Radiationenhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway. Oncogene 25: 7009-7018, 2006.
    • (2006) Oncogene , vol.25 , pp. 7009-7018
    • Cheng, J.C.1    Chou, C.H.2    Kuo, M.L.3    Hsieh, C.Y.4
  • 9
    • 42349084337 scopus 로고    scopus 로고
    • Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: Novel insights into visfatin-induced angiogenesis
    • Adya R, Tan BK, Punn A, Chen J and Randeva HS: Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: Novel insights into visfatin-induced angiogenesis. Cardiovasc Res 78: 356-365, 2008.
    • (2008) Cardiovasc Res , vol.78 , pp. 356-365
    • Adya, R.1    Tan, B.K.2    Punn, A.3    Chen, J.4    Randeva, H.S.5
  • 10
    • 0036845163 scopus 로고    scopus 로고
    • Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes
    • Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M and Carson DA: Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis Rheum 46: 2867-2877, 2002.
    • (2002) Arthritis Rheum , vol.46 , pp. 2867-2877
    • Sen, M.1    Reifert, J.2    Lauterbach, K.3    Wolf, V.4    Rubin, J.S.5    Corr, M.6    Carson, D.A.7
  • 11
    • 0037392052 scopus 로고    scopus 로고
    • Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells
    • Yang JM, Xu Z, Wu H, Zhu H, Wu X and Hait WN: Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res 1: 420-427, 2003.
    • (2003) Mol Cancer Res , vol.1 , pp. 420-427
    • Yang, J.M.1    Xu, Z.2    Wu, H.3    Zhu, H.4    Wu, X.5    Hait, W.N.6
  • 12
    • 0033032317 scopus 로고    scopus 로고
    • Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
    • S ethi T, Rintoul RC, Moore SM, MacKinnon AC, Salter D, Choo C, Chilvers ER, Dransfield I, Donnelly SC, Strieter R, et al: Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 5: 662-668, 1999.
    • (1999) Nat Med , vol.5 , pp. 662-668
    • Ethi T, S.1    Rintoul, R.C.2    Moore, S.M.3    Mackinnon, A.C.4    Salter, D.5    Choo, C.6    Chilvers, E.R.7    Dransfield, I.8    Donnelly, S.C.9    Strieter, R.10
  • 13
    • 84894285024 scopus 로고    scopus 로고
    • CXC chemokines and chemokine receptors in gastric cancer: From basic findings towards therapeutic targeting
    • Lee HJ, Song IC, Yun HJ, Jo DY and Kim S: CXC chemokines and chemokine receptors in gastric cancer: From basic findings towards therapeutic targeting. World J Gastroenterol 20: 1681-1693, 2014.
    • (2014) World J Gastroenterol , vol.20 , pp. 1681-1693
    • Lee, H.J.1    Song, I.C.2    Yun, H.J.3    Jo, D.Y.4    Kim, S.5
  • 14
    • 82855161257 scopus 로고    scopus 로고
    • Chemokines in tumor development and progression
    • Mukaida N and Baba T: Chemokines in tumor development and progression. Exp Cell Res 318: 95-102, 2012.
    • (2012) Exp Cell Res , vol.318 , pp. 95-102
    • Mukaida, N.1    Baba, T.2
  • 15
    • 84897513740 scopus 로고    scopus 로고
    • Regulation of chemokine expression in the tumor microenvironment
    • Gorbachev AV and Fairchild RL: Regulation of chemokine expression in the tumor microenvironment. Crit Rev Immunol 34: 103-120, 2014.
    • (2014) Crit Rev Immunol , vol.34 , pp. 103-120
    • Gorbachev, A.V.1    Fairchild, R.L.2
  • 16
    • 84865502454 scopus 로고    scopus 로고
    • CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer
    • Kawamura M, Toiyama Y, Tanaka K, Saigusa S, Okugawa Y, Hiro J, Uchida K, Mohri Y, Inoue Y and Kusunoki M: CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer. Eur J Cancer 48: 2244-2251, 2012.
    • (2012) Eur J Cancer , vol.48 , pp. 2244-2251
    • Kawamura, M.1    Toiyama, Y.2    Tanaka, K.3    Saigusa, S.4    Okugawa, Y.5    Hiro, J.6    Uchida, K.7    Mohri, Y.8    Inoue, Y.9    Kusunoki, M.10
  • 17
    • 84895826238 scopus 로고    scopus 로고
    • CXCL5 contributes to tumor metastasis and recurrence of intrahepatic cholangiocarcinoma by recruiting infiltrative intratumoral neutrophils
    • Zhou SL, Dai Z, Zhou ZJ, Chen Q, Wang Z, Xiao YS, Hu ZQ, Huang XY, Yang GH, Shi YH, et al: CXCL5 contributes to tumor metastasis and recurrence of intrahepatic cholangiocarcinoma by recruiting infiltrative intratumoral neutrophils. Carcinogenesis 35: 597-605, 2014.
    • (2014) Carcinogenesis , vol.35 , pp. 597-605
    • Zhou, S.L.1    Dai, Z.2    Zhou, Z.J.3    Chen, Q.4    Wang, Z.5    Xiao, Y.S.6    Hu, Z.Q.7    Huang, X.Y.8    Yang, G.H.9    Shi, Y.H.10
  • 18
    • 79951788011 scopus 로고    scopus 로고
    • CXCL5/ ENA78 increased cell migration and epithelial-to-mesenchymal transition of hormone-independent prostate cancer by early growth response-1/snail signaling pathway
    • Kuo PL, Chen YH, Chen TC, Shen KH and Hsu YL: CXCL5/ ENA78 increased cell migration and epithelial-to-mesenchymal transition of hormone-independent prostate cancer by early growth response-1/snail signaling pathway. J Cell Physiol 226: 1224-1231, 2011.
    • (2011) J Cell Physiol , vol.226 , pp. 1224-1231
    • Kuo, P.L.1    Chen, Y.H.2    Chen, T.C.3    Shen, K.H.4    Hsu, Y.L.5
  • 22
    • 84897983865 scopus 로고    scopus 로고
    • CXCL5 knockdown expression inhibits human bladder cancer T24 cells proliferation and migration
    • Zheng J, Zhu X and Zhang J: CXCL5 knockdown expression inhibits human bladder cancer T24 cells proliferation and migration. Biochem Biophys Res Commun 446: 18-24, 2014.
    • (2014) Biochem Biophys Res Commun , vol.446 , pp. 18-24
    • Zheng, J.1    Zhu, X.2    Zhang, J.3
  • 23
    • 84901437003 scopus 로고    scopus 로고
    • Signaling specificity in the Akt pathway in biology and disease
    • Toker A and Marmiroli S: Signaling specificity in the Akt pathway in biology and disease. Adv Biol Regul 55: 28-38, 2014.
    • (2014) Adv Biol Regul , vol.55 , pp. 28-38
    • Toker, A.1    Marmiroli, S.2
  • 24
    • 84929938917 scopus 로고    scopus 로고
    • Enhanced growth inhibition by combined two pathway inhibitors on K-ras mutated non-small cell lung cancer cells
    • In Chinese
    • Yang Z, Li Z, Feng H, Bian X, Liu Y and Liu Y: Enhanced growth inhibition by combined two pathway inhibitors on K-ras mutated non-small cell lung cancer cells. Zhonghua Zhong Liu Za Zhi 36: 645-650, 2014 (In Chinese).
    • (2014) Zhonghua Zhong Liu Za Zhi , vol.36 , pp. 645-650
    • Yang, Z.1    Li, Z.2    Feng, H.3    Bian, X.4    Liu, Y.5    Liu, Y.6
  • 25
    • 84896401739 scopus 로고    scopus 로고
    • Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway
    • Polivka J Jr and Janku F: Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway. Pharmacol Ther 142: 164-175, 2014.
    • (2014) Pharmacol Ther , vol.142 , pp. 164-175
    • Polivka, J.1    Janku, F.2
  • 26
    • 84918839180 scopus 로고    scopus 로고
    • Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: Its potential use in the treatment of bladder cancers
    • Houédé N and Pourquier P: Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: Its potential use in the treatment of bladder cancers. Pharmacol Ther 145: 1-18, 2015.
    • (2015) Pharmacol Ther , vol.145 , pp. 1-18
    • Houédé, N.1    Pourquier, P.2
  • 28
    • 84892901087 scopus 로고    scopus 로고
    • Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC
    • Heavey S, O'Byrne KJ and Gately K: Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC. Cancer Treat Rev 40: 445-456, 2014.
    • (2014) Cancer Treat Rev , vol.40 , pp. 445-456
    • Heavey, S.1    O'Byrne, K.J.2    Gately, K.3
  • 30
    • 84901623974 scopus 로고    scopus 로고
    • CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment
    • Würth R, Bajetto A, Harrison JK, Barbieri F and Florio T: CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment. Front Cell Neurosci 8: 144, 2014.
    • (2014) Front Cell Neurosci , vol.8 , pp. 144
    • Würth, R.1    Bajetto, A.2    Harrison, J.K.3    Barbieri, F.4    Florio, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.