Participation in a 1,000-mile race increases the oxidation of carbohydrate in Alaskan sled dogs

Journal of Applied Physiology

Volumn 118, Issue 12, 2015, Pages 1502-1509

  Miller, Benjamin F ^a   Drake, Joshua C ^a   Peelor, Frederick F ^a   Biela, Laurie M ^a   Geor, Raymond ^b   Hinchcliff, Kenneth ^c   Davis, Michael ^d   Hamilton, Karyn L ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Canine; Carbohydrate; Exercise; Stable isotope; Substrate

Indexed keywords

BICARBONATE; GLUCOSE; GLYCEROL; LACTIC ACID;

ALGORITHM; ANAEROBIC THRESHOLD; ANIMAL; ANIMAL EXPERIMENT; CARBOHYDRATE METABOLISM; DOG; ENDURANCE; FEMALE; KINETICS; LIPID METABOLISM; MALE; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; RUNNING;

ALGORITHMS; ANAEROBIC THRESHOLD; ANIMALS; BICARBONATES; CARBOHYDRATE METABOLISM; DOGS; FEMALE; GLUCOSE; GLYCEROL; KINETICS; LACTIC ACID; LIPID METABOLISM; MALE; OXIDATION-REDUCTION; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; RUNNING;

EID: 84932110818     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00588.2014     Document Type: Article

References (29)

1. 2max and submaximal blood lactate concentrations of untrained sled dogs. Equine Comp Exer Physiol 4: 89-94, 2007.
2. Brooks GA, Mercier J. Balance of carbohydrate and lipid utilization during exercise: the "crossover" concept. J Appl Physiol 76: 2253-2261, 1994.
3. Burke LM, Kiens B, Ivy JL. Carbohydrates and fat for training and recovery. J Sports Sci 22: 15-30, 2004.
4. Camacho RC, Lacy DB, James FD, Coker RH, Wasserman DH. Hepatic glucose autoregulation: responses to small, non-insulin-induced changes in arterial glucose. Am J Physiol Endocrinol Metab 287: E269-E274, 2004.
5. Casazza GA, Jacobs KA, Suh SH, Miller BF, Horning MA, Brooks GA. Menstrual cycle phase and oral contraceptive effects on triglyceride mobilization during exercise. J Appl Physiol 97: 302-309, 2004.
6. Emhoff CAW, Messonnier LA, Horning MA, Fattor JA, Carlson TJ, Brooks GA. Direct and indirect lactate oxidation in trained and untrained men. J Appl Physiol 115: 829-838, 2013.
7. Geor RJ. New methods for assessing substrate utilization in horses during exercise. In: Advances in Equine Nutrition II. Nottingham, UK: Nottingham University Press, 2001.
8. Green HJ. How important is endogenous muscle glycogen to fatigue in prolonged exercise? Can J Physiol Pharmacol 69: 290-297, 1991.
9. Gross RC, Eigenbrodt EH, Farquhar JW. Endogenous triglyceride turnover in liver and plasma of the dog. Journal of Lipid Research 8: 114-125, 1967.
10. Hill RC. The nutritional requirements of exercising dogs. J Nutr 128:2686S-2690S, 1998.
11. Hinchcliff KW, Reinhart GA, Burr JR, Schreier CJ, Swenson RA. Metabolizable energy intake and sustained energy expenditure of Alaskan sled dogs during heavy exertion in the cold. Am J Vet Res 58: 1457-1462, 1997.
12. 13C]bicarbonate kinetics in humans: intra- vs. interindividual variations. Am J Physiol Regul Integr Comp Physiol 245: R190-R202, 1983.
13. Kirkwood Minireview JK. A limit to metabolisable energy intake in mammals and birds. Comp Biochem Physiol A Comp Physiol 75: 1-3, 1983.
14. Lighton JRB. Measuring Metabolic Rates: A Manual for Scientists. Oxford, UK: Oxford University Press, 2008.
15. 2 consumption during exercise in dogs-roles of splenic contraction and alpha-adrenergic vasoconstriction. Am J Physiol Heart Circ Physiol 251: H502-H509, 1986.
16. McKenzie E, Holbrook T, Williamson K, Royer C, Valberg S, Hinchcliff K, Jose-Cunilleras E, Nelson S, Willard M, Davis M. Recovery of muscle glycogen concentrations in sled dogs during prolonged exercise. Med Sci Sports Exerc 37: 1307-1312, 2005.
17. Miller BF, Fattor JA, Jacobs KA, Horning MA, Navazio F, Lindinger MI, Brooks GA. Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion. Journal of Physiology 544: 963-975, 2002.
18. Miller BF, Fattor JA, Jacobs KA, Horning MA, Suh SH, Navazio F, Brooks GA. Metabolic and cardiorespiratory responses to "the lactate clamp." Am J Physiol Endocrinol Metab 283: E889-E898, 2002.
19. Newsholme EA, Crabtree B. Substrate cycles in metabolic regulation and in heat generation. Biochem Soc Symp 41: 61-109, 1976.
20. Rehrer NJ, Hellemans IJ, Rolleston AK, Rush E, Miller BF. Energy intake and expenditure during a 6-day cycling stage race. Scandinavian Journal of Medicine & Science in Sports 20: 609-618, 2010.
21. Reidy SP, Weber JM. Accelerated substrate cycling: a new energy-wasting role for leptin in vivo. Am J Physiol Endocrinol Metab 282: E312-E317, 2002.
22. Roberts TJ, Weber JM, Hoppeler H, Weibel ER, Taylor CR. Design of the oxygen and substrate pathways. II. Defining the upper limits of carbohydrate and fat oxidation. J Exp Biol 199: 1651-1658, 1996.
23. Sakurai Y, Zhang XJ, Wolfe RR. TNF directly stimulates glucose uptake and leucine oxidation and inhibits FFA flux in conscious dogs. Am J Physiol Endocrinol Metab 270: E864-E872, 1996.
24. Shaw WA, Issekutz TB, Issekutz B. Gluconeogenesis from glycerol at rest and during exercise in normal, diabetic, and methylprednisolone-treated dogs. Metab Clin Exp 25: 329-339, 1976.
25. 3 infusions. Am J Physiol Endocrinol Metab 281: E683-E692, 2001.
26. Weber JM, Brichon G, Zwingelstein G, McClelland G, Saucedo C, Weibel ER, Taylor CR. Design of the oxygen and substrate pathways. IV. Partitioning energy provision from fatty acids. J Exp Biol 199: 1667-1674, 1996.
27. Weber JM, Roberts TJ, Vock R, Weibel ER, Taylor CR. Design of the oxygen and substrate pathways. III. Partitioning energy provision from carbohydrates. J Exp Biol 199: 1659-1666, 1996.
28. Westerterp KR, Saris WH, van Es M, Hoor ten F. Use of the doubly labeled water technique in humans during heavy sustained exercise. J Appl Physiol 61: 2162-2167, 1986.
29. nd Ed.). New York: Wiley, 2005.