Menstrual cycle phase and oral contraceptive effects on triglyceride mobilization during exercise

Journal of Applied Physiology

Volumn 97, Issue 1, 2004, Pages 302-309

  Casazza, Gretchen A ^a   Jacobs, Kevin A ^a   Suh, Sang Hoon ^a   Miller, Benjamin F ^a   Horning, Michael A ^a   Brooks, George A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Exertion; Glycerol kinetics; Lipolysis; Substrate utilization; Synthetic steroids

Indexed keywords

DEUTERIUM; ETHINYLESTRADIOL; GLYCEROL; GROWTH HORMONE; HYDROCORTISONE; NORGESTIMATE; ORAL CONTRACEPTIVE AGENT; STEROID HORMONE; TRIACYLGLYCEROL;

ADULT; ARTICLE; CARBOHYDRATE INTAKE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET; DRUG MEGADOSE; DRUG USE; ENERGY METABOLISM; ERGOMETRY; EXERCISE; FEMALE; FOLLICULAR PHASE; GLYCEROL BLOOD LEVEL; GROWTH HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; LIPID ABSORPTION; LIPID METABOLISM; LIPOLYSIS; LUNG GAS EXCHANGE; LUTEAL PHASE; MENSTRUAL CYCLE; NORMAL HUMAN; ORAL CONTRACEPTION; OXYGEN CONSUMPTION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANAEROBIC THRESHOLD; BLOOD GLUCOSE; CONTRACEPTIVES, ORAL, HORMONAL; DIETARY CARBOHYDRATES; ESTRADIOL; EXERCISE; FATTY ACIDS, NONESTERIFIED; FEMALE; GLYCEROL; HUMAN GROWTH HORMONE; HUMANS; HYDROCORTISONE; KINETICS; LIPOLYSIS; MENSTRUAL CYCLE; PROGESTERONE; TRIGLYCERIDES;

EID: 3042563869     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00050.2004     Document Type: Article

References (42)

1. Aden U, Jung-Hoffmann C, and Kuhl H. A randomized cross-over study on various hormonal parameters of two triphasic oral contraceptives. Contraception 58: 75-81, 1998.
2. Bemben DA, Boileau RA, Bahr JM, Nelson RA, and Misner JE. Effects of oral contraceptives on hormonal and metabolic responses during exercise. Med Sci Sports Exerc 24: 434-441, 1992.
3. Bemben DA, Salm PC, and Salm AJ. Ventilatory and blood lactate responses to maximal exercise during the menstrual cycle. J Sports Med Phys Fitness 35: 257-262, 1995.
4. Bessinger RC, McMurray RG, and Hackney AC. Substrate utilization and hormonal responses to moderate intensity exercise during pregnancy and after delivery. Am J Obstet Gynecol 186: 757-764, 2002.
5. Bonen A, Haynes FJ, and Graham TE. Substrate and hormonal responses to exercise in women using oral contraceptives. J Appl Physiol 70: 1917-1927, 1991.
6. Bonen A, Haynes FJ, Watson-Wright W, Sopper MM, Pierce GN, Low MP, and Graham TE. Effects of menstrual cycle on metabolic responses to exercise. J Appl Physiol 55: 1506-1513, 1983.
7. Braun B, Mawson JT, Muza SR, Dominick SB, Brooks GA, Horning MA, Rock PB, Moore LG, Mazzeo RS, Ezeji-Okoye SC, and Butterfield GE. Women at altitude: carbohydrate utilization during exercise at 4,300 m. J Appl Physiol 88:246-256, 2000.
8. Brooks GA and Mercier J. Balance of carbohydrate and lipid utilization during exercise: the "crossover" concept. J Appl Physiol 76: 2253-2261, 1994.
9. Bunt JC. Metabolic actions of estradiol: significance for acute and chronic exercise responses. Med Sci Sports Exerc 22: 286-290, 1990.
10. Butte NF, Hopkinson JM, Mehta N, Moon JK, and Smith EO. Adjustments in energy expenditure and substrate utilization during late pregnancy and lactation. Am J Clin Nutr 69: 299-307, 1999.
11. Campbell SE, Angus DJ, and Febbraio MA. Glucose kinetics and exercise performance during phases of the menstrual cycle: effect of glucose ingestion. Am J Physiol Endocrinol Metab 281: E817-E825, 2001.
12. Campbell SE and Febbraio MA. Effect of ovarian hormones on mitochondrial enzyme activity in the fat oxidation pathway of skeletal muscle. Am J Physiol Endocrinol Metab 281: E803-E808, 2001.
13. a but not whole body metabolism during endurance exercise. J Appl Physiol 90: 139-146, 2001.
14. Casazza GA, Suh SH, Miller BF, and Brooks GA. Effects of oral contraceptives on peak exercise capacity. J Appl Physiol 93: 1698-1702, 2002.
15. Crook D. Multicenter study of endocrine function and plasma lipids and lipoproteins in women using oral contraceptives containing desogestrel progestin. UK desogen study group. Contraception 55: 219-224, 1997.
16. De Souza MJ, Maguire MS, Rubin KR, and Maresh CM. Effects of menstrual phase and amenorrhea on exercise performance in runners. Med Sci Sports Exerc 22: 575-580, 1990.
17. Dombovy ML, Bonekat HW, Williams TJ, and Staats BA. Exercise performance and ventilatory response in the menstrual cycle. Med Sci Sports Exerc 19: 111-117, 1987.
18. Ellis GS, Lanza-Jacoby S, Gow A, and Kendrick ZV. Effects of estradiol on lipoprotein lipase activity and lipid availability in exercised male rats. J Appl Physiol 77: 209-215, 1994.
19. Friedlander AL, Casazza GA, Horning MA, Huie MJ, Piacentini MF, Trimmer JK, and Brooks GA. Training-induced alterations of carbohydrate metabolism in women: women respond differently from men. J Appl Physiol 85: 1175-1186, 1998.
20. Friedlander AL, Casazza GA, Horning MA, Usaj A, and Brooks GA. Endurance training increases fatty acid turnover, but not fat oxidation, in young men. J Appl Physiol 86: 2097-2105, 1999.
21. Hackney AC. Influence of oestrogen on muscle glycogen utilization during exercise. Acta Physiol Scand 167: 273-274, 1999.
22. 2 delivery, and performance during exercise. J Appl Physiol 51: 1493-1499, 1981.
23. Horning MA, Friedlander AL, Casazza GA, Huie MA, and Brooks GA. Arterial and "arterialized" sampling sites do not change isotopic enrichment using [6,6-D-glucose] and [1,1,2,3,3-D-glycerol] (Abstract). FASEB J 12: A854, 1998.
24. Horton TJ, Miller EK, Glueck D, and Tench K. No effect of menstrual cycle phase on glucose kinetics and fuel oxidation during moderate-intensity exercise. Am J Physiol Endocrinol Metab 282: E752-E762, 2002.
25. Horton TJ, Pagliassotti MJ, Hobbs K, and Hill JO. Fuel metabolism in men and women during and after long-duration exercise. J Appl Physiol 85: 1823-1832, 1998.
26. Hoyenga KB and Hoyenga KT. Gender and energy balance: sex differences in adaptations for feast and famine. Physiol Behav 28: 545-563, 1982.
27. Kanaley JA, Boileau RA, Bahr JA, Misner JE, and Nelson RA. Substrate oxidation and GH responses to exercise are independent of menstrual phase and status. Med Sci Sports Exerc 24: 873-880, 1992.
28. Larsen PR, Kronenberg HM, Melmed S, and Polonsky KS. Williams Textbook of Endocrinology. Philadelphia, PA: Saunders, 2003, p. 500-506.
29. Lavoie JM, Dionne N, Helie R, and Brisson GR. Menstrual cycle phase dissociation of blood glucose homeostasis during exercise. J Appl Physiol 62: 1084-1089, 1987.
30. Lebrun CM, McKenzie DC, Prior JC, and Taunton JE. Effects of menstrual cycle phase on athletic performance. Med Sci Sports Exerc 27: 437-444, 1995.
31. Lynch NJ and Nimmo MA. Effects of menstrual cycle and oral contraceptive use on intermittent exercise. Eur J Appl Physiol 78: 565-572, 1998.
32. McMurray RG, Mottola MF, Wolfe LA, Artal R, Millar L, and Pivarnik JM. Recent advances in understanding maternal and fetal responses to exercise. Med Sci Sports Exerc 25: 1305-1321, 1993.
33. Miller KE and Klibanski A. Amenorrheic bone loss. J Clin Endocrinol Metab 84: 1775-1783, 1999.
34. Nicklas BJ, Hackney AC, and Sharp RL. The menstrual cycle and exercise: performance, muscle glycogen, and substrate responses. Int J Sports Med 10: 264-269, 1989.
35. Phillips SM, Atkinson SA, Tarnopolsky MA, and MacDougall JD. Gender differences in leucine kinetics and nitrogen balance in endurance athletes. J Appl Physiol 75: 2134-2141, 1993.
36. Ruby BC, Robergs RA, Waters DL, Burge M, Mermier C, and Stolarczyk L. Effects of estradiol on substrate turnover during exercise in amenorrheic females. Med Sci Sports Exerc 29: 1160-1169, 1997.
37. Shepard MK and Senturia YD. Comparison of serum progesterone and endometrial biopsy for confirmation of ovulation and evaluation of luteal function. Fertil Steril 28: 541-548, 1977.
38. Suh SH, Casazza GA, Horning MA, Miller BF, and Brooks GA. Luteal and follicular glucose fluxes during rest and exercise in 3-h postabsorptive women. J Appl Physiol 93: 42-50, 2002.
39. Suh SH, Casazza GA, Horning MA, Miller BF, and Brooks GA. Effects of oral contraceptives on glucose flux and substrate oxidation rates during rest and exercise. J Appl Physiol 94: 285-294, 2003.
40. Tarnopolsky LJ, MacDougall JD, Atkinson SA, Tarnopolsky MA, and Sutton JR. Gender differences in substrate for endurance exercise. J Appl Physiol 68: 302-308, 1990.
41. Wolfe RR. Radioactive and Stable Isotope Tracers in Biomedicine: Principles and Practice of Kinetic Analysis. New York: Wiley-Liss, 1992.
42. Zderic TW, Coggan AR, and Ruby BC. Glucose kinetics and substrate oxidation during exercise in the follicular and luteal phases. J Appl Physiol 90: 447-453, 2001.