The effects of aerobic, resistance, and combination training on insulin sensitivity and secretion in overweight adults from STRRIDE AT/RT: A randomized trial

Journal of Applied Physiology

Volumn 118, Issue 12, 2015, Pages 1474-1482

  AbouAssi, Hiba ^a   Slentz, Cris A ^b   Mikus, Catherine R ^b   Tanner, Charles J ^c   Bateman, Lori A ^b   Willis, Leslie H ^b   Shields, A Tamlyn ^c   Piner, Lucy W ^b   Penry, Lorrie E ^b   Kraus, Erik A ^b   Huffman, Kim M ^d   Bales, Connie W ^a   Houmard, Joseph A ^c   Kraus, William E ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EAST CAROLINA UNIVERSITY   (United States)

^d DURHAM VA MEDICAL CENTER   (United States)

Author keywords

Aerobic exercise; Exercise intervention; Insulin sensitivity; IVGTT; Resistance exercise

Indexed keywords

GLUCOSE; INSULIN;

ADOLESCENT; ADULT; AGED; ANAEROBIC THRESHOLD; BLOOD; BODY COMPOSITION; CONTROLLED STUDY; DYSLIPIDEMIA; EXERCISE; FEMALE; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN RESISTANCE; MALE; METABOLISM; MIDDLE AGED; OVERWEIGHT; PANCREAS ISLET BETA CELL; PHYSICAL EDUCATION; PHYSIOLOGY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING; RISK REDUCTION; SEDENTARY LIFESTYLE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANAEROBIC THRESHOLD; BODY COMPOSITION; DYSLIPIDEMIAS; EXERCISE; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; OVERWEIGHT; PHYSICAL EDUCATION AND TRAINING; RESISTANCE TRAINING; RISK REDUCTION BEHAVIOR; SEDENTARY LIFESTYLE; YOUNG ADULT;

EID: 84932093153     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00509.2014     Document Type: Article

References (32)

1. Bajpeyi S, Tanner C, Slentz C, Duscha B, McCartney J, Hickner R, Kraus W, Houmard J. Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation. J Appl Physiol 106: 1079-1085, 2009.
2. Ball S, Altena T. Comparison of the BodPod and DEXA in men. Physiol Meas 25: 671-678, 2004.
3. Bateman L, Slentz C, Willis L, Shields A, Piner L, Bales C, Houmard J, Kraus W. Comparison of aerobic versus resistance exercise training on metaoblic syndrome (from Studies of a Targeted Risk Reduction Intervention Through Defined Exercies-STRRIDE AT/RT). Am J Cardiol 108: 838-844, 2011.
4. Bergman R, Finegood D, Ader M. Assessment of insulin sensitivity in vivo. Endocr Rev 6: 45-86, 1985.
5. Brochu M, Starling R, Tchernof A, Matthews D, Garcia-Rubi E, Poehlman E. Visceral adipose tissue is an independent correlate of glucose disposal in older obese postmenopausal women. J Clin Endocrinol Metab 85: 2378-2384, 2000.
6. Church T, Blair S, Cocreham S, Johannsen N, Johnson W, Kramer K, Mikus C, Myers V, Nauta M, Rodarte R, Sparks L, Thompson A, Earnest C. Effects of aerobic and resistance training on HbA1c in patients with type 2 diabetes-a randomized, controlled trial. JAMA 304: 2253-2262, 2010.
7. Davidson LE, Hudson R, Kilpatrick K, Kuk JL, McMillan K, Janiszewski PM, Lee S, ML, Ross R. Effects of exercise modality on insulin resistance and functional limitation in older adults: a randomized controlled trial. Arch Intern Med 169: 122-131, 2009.
8. Duscha B, Slentz C, Johnson J, Houmard J, Bensimhon D, Knetgzer K, Kraus W. Effects of exercise training amount and intensity on peak oxygen comsumption in middle-aged men and women at risk for cardio-vascular disease. Chest 128: 2788-2793, 2005.
9. Fletcher GF, Ades PA, Kligfield P, Arena R, Balady GJ, Bittner VA, Coke LA, Fleg JL, Forman DE, Gerber TC, Gulati M, Madan K, Rhodes J, Thompson PD, Williams MA; American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee of the Council on Clinical Cardiology, Council on Nutrition, Physical Activity and Metabolism, Council on Cardiovascular and Stroke Nursing, and Council on Epidemiology and Prevention. Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation 128: 873-934, 2013.
10. Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP; American College of Sports Medicine. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43: 1334-1359, 2011.
11. Goodyear L, Kahn B. Exercise, glucose transport, and insulin sensitivity. Annu Rev Med 49: 235-261, 1998.
12. Henriksen E. Exercise effects of muscle insulin signaling and action. Invited Review: Effects of acute exercise and exercise training on insulin resistance. J Appl Physiol 93: 788-796, 2001.
13. Holloszy J, Schultz J, Kusnierkiewicz J, Hagberg J, Ehsani A. Effects of exercise on glucose tolerance and insulin resistance. Brief review and some preliminary results. Acta Med Scand Suppl 711: 55-65, 1986.
14. Houmard J, Hortobagyi T, Neufer P, Johns R, Fraser D, Isreal R, Dohm G. Training cessation does not alter muscular GLUT-4 protein levels. J Appl Physiol 74: 776-781, 1993.
15. Houmard J, Tanner C, Slentz C, Duscha B, McCartney J, Kraus W. Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol 96: 101-106, 2004.
16. Johnson J, Slentz C, Houmard J, Samsa G, Duscha B, Aiken L, McCartney J, Tanner C, Kraus W. Exercise training amount and intensity effects on metabolic syndrome: STRRIDE. Am J Cardiol 100: 1759-1767, 2007.
17. Kraemer F, Ginsberg H, Gerald M, Reaven MD. Demonstration of the central role of insulin resistance in type 2 diabetes and cardiovascular disease. Diabetes Care 37: 1178-1181, 2014.
18. Kraus W, Houmard J, Duscha B, Knetgzer K, Wharton M, McCartney J, Bales C, Henes S, Samsa G, Otvos J, Kulkarni K, Slentz C. Effects of the amount and intensity of exercise on plasma lipoproteins. N Engl J Med 347: 1483-1492, 2002.
19. Kraus W, Slentz C. Metabolic syndrome: recognition, etiology and physical fitness as a component. In: Nutrition and Diabetes: Pathophysiology and Management, edited by Opara E. Boca Raton, FL: Taylor &Francis Group, CRC Press, 2006, p. 57-78.
20. Kraus W, Torgan C, Duscha B, Norris J, Brown S, Cobb F, Bales C, Annex B, Samsa G, Houmard J, Slentz C. Studies of a targeted risk reduction intervention through defined exercise (STRRIDE). Med Sci Sports Exerc 33: 1774-1784, 2001.
21. Layne A, Nasrallah S, South M, Howell M, McCurry M, Ramsey M, Stone M, Stuart C. Impaired muscle AMPK activation in the metabolic syndrome may attenuate improved insulin action after exercise training. J Clin Endocrinol Metab 96: 1815-1826, 2011.
22. Malin S, Hinnerichs K, Echtenkamp B, Evetovich T, Engebretsen B. Effect of adiposity on insulin action after acute and chronic resistance exercise in non-diabetic women. Eur J Appl Physiol 113: 2933-2941, 2013.
23. Ross R, Fortier L, Hudson R. Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women. Diabetes Care 19: 1404-1411, 1996.
24. Sigal R, Kenny G, Wasserman D, Castaneda-Sceppa C, White R. Physical activity/exercise and type 2 diabetes: a consensus statement from the ADA. Diabetes Care 29: 1433-1438, 2006.
25. Sigal RJ, Kenny GP, Boule NG, Wells GA, Prud'homme D, Fortier M. Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial. Ann Intern Med 147: 357-369, 2007.
26. Slentz C, Aiken L, Houmard J, Bales C, Johnson J, Tanner C, Duscha B, Kraus W. Inactivity, exercise and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol 99: 1613-1618, 2005.
27. Slentz C, Bateman L, Willis L, Shields A, Tanner C, Piner L, Hawk V, Muehlbauer M, Samsa G, Nelson R, Huffman K, Bales C, Houmard J, Kraus W. Effects of aerobic vs resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT. Am J Physiol Endocrinol Metab 301: E1033-E1039, 2011.
28. Slentz C, Houmard J, Johnson J, Bateman L, Tanner C, McCartney J, Duscha B, Kraus W. Inactivity, exercise training and detraining, and plasma lipoproteisn. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol 103: 432-442, 2007.
29. Slentz C, Tanner C, Bateman L, Durheim M, Huffman K, Houmard J, Kraus W. Effects of exercise training intensity on pancreatic beta cell function. Diabetes Care 32: 1807-1811, 2009.
30. Slentz C, Torgan C, Houmard J, Tanner C, Kraus W. Long-term effects of exercise training and detraining on carbohydrate metabolism in overweight subjects. Clin Exerc Physiol 4: 22-28, 2002.
31. Willis L, Slentz C, Houmard J, Johnson J, Duscha B, Aiken L, Kraus W. Minimal versus umbilical waist circumference measures as indicators of cardiovascular disease risk. Obesity (Silver Spring) 15: 753-759, 2007.
32. Zuntz N. Thermal equivalent of oxygen consumption for nonprotein respiratory quotient. Pflugers Arch 83: 557, 1901.