Biodistribution and pharmacokinetic studies of SPION using particle electron paramagnetic resonance, MRI and ICP-MS

Nanomedicine

Volumn 10, Issue 11, 2015, Pages 1751-1760

  Gobbo, Oliviero L ^a,b   Wetterling, Friedrich ^b   Vaes, Peter ^c   Teughels, Stephanie ^c   Markos, Farouk ^d   Edge, Deirdre ^d   Shortt, Christine M ^d   Crosbie Staunton, Kieran ^e   Radomski, Marek W ^a   Volkov, Yuri ^b,e   Prina Mello, Adriele ^b,e  

^a School of Pharmacy and Pharmaceutical Sciences   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c PEPRIC NV   (Belgium)

^d UNIVERSITY COLLEGE CORK   (Ireland)

^e Autism Genetics Group   (Ireland)

Author keywords

biodistribution; ICP MS; MRI; nanomedicine; pEPR; pharmacokinetics; SPION

Indexed keywords

IRON; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; CONTRAST MEDIUM; FERRIC ION; FERRIC OXIDE; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BRAIN; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG TISSUE LEVEL; ELECTRON SPIN RESONANCE; HALF LIFE TIME; HEART; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; KIDNEY MEDULLA; LIVER; LUNG; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SPLEEN; ANIMAL; CHEMISTRY; HUMAN; NANOMEDICINE; TISSUE DISTRIBUTION;

ANIMALS; CONTRAST MEDIA; ELECTRON SPIN RESONANCE SPECTROSCOPY; FERRIC COMPOUNDS; HUMANS; MAGNETIC RESONANCE IMAGING; NANOMEDICINE; NANOPARTICLES; RATS; TISSUE DISTRIBUTION;

EID: 84931830692     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.15.22     Document Type: Article

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