Development of a method to screen and isolate potential α-glucosidase inhibitors from Panax japonicus C.A. Meyer by ultrafiltration, liquid chromatography, and counter-current chromatography

Journal of Separation Science

Volumn 38, Issue 12, 2015, Pages 2014-2023

  Li, Sainan ^a   Tang, Ying ^a   Liu, Chunming ^a   Zhang, Yuchi ^a  

^a CHANGCHUN NORMAL UNIVERSITY   (China)

Author keywords

High speed counter current chromatography; Panax japonicus C.A. Meyer; Saponins; Glucosidase inhibitors

Indexed keywords

CHLORINE COMPOUNDS; CHROMATOGRAPHY; DICHLOROMETHANE; DRUG PRODUCTS; FORMIC ACID; LIGANDS; LIQUIDS; MASS SPECTROMETRY; METABOLITES; ORGANIC SOLVENTS; SCREENING; SPECTROMETRY; ULTRAFILTRATION;

BIOACTIVE COMPOUNDS; COUNTERCURRENT CHROMATOGRAPHY; GLUCOSIDASE INHIBITORS; HIGH-SPEED COUNTER CURRENT CHROMATOGRAPHY; PANAX JAPONICUS C.A. MEYER; SAPONINS; TERT-BUTYL METHYL ETHERS; TWO-PHASE SOLVENT SYSTEM;

LIQUID CHROMATOGRAPHY;

2 PROPANOL; ACARBOSE; ACETONITRILE; ALPHA GLUCOSIDASE INHIBITOR; BUTANOL; CHIKUSETSU SAPONIN; DICHLOROMETHANE; FORMIC ACID; GINSENOSIDE RB 1; GINSENOSIDE RD; METHANOL; NOTOGINSENOSIDE R 1; SAPONIN; TERT BUTYL METHYL ETHER; UNCLASSIFIED DRUG; ACETONITRILE DERIVATIVE; ALPHA GLUCOSIDASE; CHIKUSETSU SAPONIN IVA; ENZYME INHIBITOR; ETHER DERIVATIVE; FORMIC ACID DERIVATIVE; GINSENOSIDE; GLYCOSIDASE INHIBITOR; LIGAND; NOTOGINSENOSIDE R1; OLEANOLIC ACID; PLANT EXTRACT; SOLVENT;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CENTRIFUGATION; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; DRUG ISOLATION; DRUG SCREENING; ELECTROSPRAY MASS SPECTROMETRY; ENZYME INHIBITION; LIQUID CHROMATOGRAPHY; MATHEMATICAL MODEL; PRIORITY JOURNAL; ROOM TEMPERATURE; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION; ANALOGS AND DERIVATIVES; CHEMISTRY; DIABETES MELLITUS; HUMAN; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MULTIVARIATE ANALYSIS; PANAX; THEORETICAL MODEL;

IVA; PANAX JAPONICUS;

ACETONITRILES; ALPHA-GLUCOSIDASES; CHROMATOGRAPHY, LIQUID; DIABETES MELLITUS; ENZYME INHIBITORS; FORMATES; GINSENOSIDES; GLYCOSIDE HYDROLASE INHIBITORS; HUMANS; LIGANDS; MASS SPECTROMETRY; METHYL ETHERS; MODELS, THEORETICAL; MULTIVARIATE ANALYSIS; OLEANOLIC ACID; PANAX; PLANT EXTRACTS; SAPONINS; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; ULTRAFILTRATION;

EID: 84931562895     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201500064     Document Type: Article

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